David Gate, PhD
David Gate, PhD
Assistant Professor, Northwestern University
Verified email at - Homepage
Cited by
Cited by
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer’s disease
D Gate, N Saligrama, O Leventhal, AC Yang, MS Unger, J Middeldorp, ...
Nature 577 (7790), 399-404, 2020
Undulating changes in human plasma proteome profiles across the lifespan
B Lehallier, D Gate, N Schaum, T Nanasi, SE Lee, H Yousef, ...
Nature medicine 25 (12), 1843-1850, 2019
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss
RM Cohen, K Rezai-Zadeh, TM Weitz, A Rentsendorj, D Gate, I Spivak, ...
Journal of Neuroscience 33 (15), 6245-6256, 2013
Dysregulation of brain and choroid plexus cell types in severe COVID-19
AC Yang, F Kern, PM Losada, MR Agam, CA Maat, GP Schmartz, ...
Nature 595 (7868), 565-571, 2021
Il10 deficiency rebalances innate immunity to mitigate Alzheimer-like pathology
MV Guillot-Sestier, KR Doty, D Gate, J Rodriguez, BP Leung, ...
Neuron 85 (3), 534-548, 2015
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk
AC Yang, RT Vest, F Kern, DP Lee, M Agam, CA Maat, PM Losada, ...
Nature 603 (7903), 885-892, 2022
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
JV Pluvinage, MS Haney, BAH Smith, J Sun, T Iram, L Bonanno, L Li, ...
Nature 568 (7751), 187-192, 2019
Physiological blood–brain transport is impaired with age by a shift in transcytosis
AC Yang, MY Stevens, MB Chen, DP Lee, D Stähli, D Gate, K Contrepois, ...
Nature 583 (7816), 425-430, 2020
CNS Infiltration of Peripheral Immune Cells: D-Day for Neurodegenerative Disease?
K Rezai-Zadeh, D Gate, T Town
Journal of Neuroimmune Pharmacology 4, 462-475, 2009
Macrophages in Alzheimer’s disease: the blood-borne identity
D Gate, K Rezai-Zadeh, D Jodry, A Rentsendorj, T Town
Journal of neural transmission 117, 961-970, 2010
The Role of LAT in Increased CD8+ T Cell Exhaustion in Trigeminal Ganglia of Mice Latently Infected with Herpes Simplex Virus 1
SJ Allen, P Hamrah, D Gate, KR Mott, D Mantopoulos, L Zheng, T Town, ...
Journal of virology 85 (9), 4184-4197, 2011
CD4+ T cells contribute to neurodegeneration in Lewy body dementia
D Gate, E Tapp, O Leventhal, M Shahid, TJ Nonninger, AC Yang, ...
Science 374 (6569), 868-874, 2021
IL-10 signaling blockade controls murine West Nile virus infection
F Bai, T Town, F Qian, P Wang, M Kamanaka, TM Connolly, D Gate, ...
PLoS pathogens 5 (10), e1000610, 2009
Increased Susceptibility of Humanized NSG Mice to Panton-Valentine Leukocidin and Staphylococcus aureus Skin Infection
CW Tseng, JC Biancotti, BL Berg, D Gate, SL Kolar, S Müller, ...
PLoS pathogens 11 (11), e1005292, 2015
IL-22 signaling contributes to West Nile encephalitis pathogenesis
P Wang, F Bai, LA Zenewicz, J Dai, D Gate, G Cheng, L Yang, F Qian, ...
Public Library of Science 7 (8), e44153, 2012
How to get from here to there: macrophage recruitment in Alzheimer's disease
K Rezai-Zadeh, D Gate, G Gowing, T Town
Current Alzheimer Research 8 (2), 156-163, 2011
Interleukin-17A Promotes CD8+ T Cell Cytotoxicity To Facilitate West Nile Virus Clearance
D Acharya, P Wang, AM Paul, J Dai, D Gate, JE Lowery, DS Stokic, ...
Journal of virology 91 (1), 10.1128/jvi. 01529-16, 2017
Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment
N Piehl, L van Olst, A Ramakrishnan, V Teregulova, B Simonton, Z Zhang, ...
Cell 185 (26), 5028-5039. e13, 2022
T-cell TGF-β signaling abrogation restricts medulloblastoma progression
D Gate, M Danielpour, J Rodriguez Jr, GB Kim, R Levy, S Bannykh, ...
Proceedings of the National Academy of Sciences 111 (33), E3458-E3466, 2014
Can peripheral leukocytes be used as Alzheimer’s disease biomarkers?
K Rezai-Zadeh, D Gate, CA Szekely, T Town
Expert review of neurotherapeutics 9 (11), 1623-1633, 2009
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