|Natural BH3 mimetic (-)-gossypol chemosensitizes human prostate cancer via Bcl-xL inhibition accompanied by increase of Puma and Noxa|
Y Meng, W Tang, Y Dai, X Wu, M Liu, Q Ji, M Ji, K Pienta, T Lawrence, ...
Molecular cancer therapeutics 7 (7), 2192-2202, 2008
|A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum|
J Lian, X Wu, F He, D Karnak, W Tang, Y Meng, D Xiang, M Ji, ...
Cell Death & Differentiation 18 (1), 60-71, 2011
|Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction|
XL Wu X, Lan L, Wilson DM, Marquez RT, Tsao WC, Gao P, Roy A, Turner B.A ...
ACS Chem Biol 10 (6), 1476-1484, 2015
|Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1|
L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ...
Molecular oncology 9 (7), 1406-1420, 2015
|Design and synthesis of novel 4-benzothiazole amino quinazolines Dasatinib derivatives as potential anti-tumor agents|
J Cai, M Sun, X Wu, J Chen, P Wang, X Zong, M Ji
European Journal of Medicinal Chemistry 63, 702-712, 2013
|Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling|
X Wu, W Tang, RT Marquez, K Li, CA Highfill, F He, J Lian, J Lin, ...
Oncotarget 7 (10), 11708, 2016
|Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity|
X Wu, M Li, Y Qu, W Tang, Y Zheng, J Lian, M Ji, L Xu
Bioorganic & medicinal chemistry 18 (11), 3812-3822, 2010
|HAb18G/CD147 Promotes pSTAT3-Mediated Pancreatic Cancer Development via CD44sHAb18G/CD147, CD44s, STAT3, and Pancreatic Cancer|
L Li, W Tang, X Wu, D Karnak, X Meng, R Thompson, X Hao, Y Li, ...
Clinical Cancer Research 19 (24), 6703-6715, 2013
|Design, synthesis, and in vitro antitumor evaluation of novel diaryl ureas derivatives|
M Sun, X Wu, J Chen, J Cai, M Cao, M Ji
European journal of medicinal chemistry 45 (6), 2299-2306, 2010
|Molecular and functional extracellular vesicle analysis using nanopatterned microchips monitors tumor progression and metastasis|
P Zhang, X Wu, G Gardashova, Y Yang, Y Zhang, L Xu, Y Zeng
Science translational medicine 12 (547), eaaz2878, 2020
|Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors|
JM Cai J, Wei H, Hong KH, Wu X, Cao M, Zong X, Li L, Sun C, Chen J
Eur J Med Chem 96, 1-13, 2015
|Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis|
X Wu, G Gardashova, L Lan, S Han, C Zhong, RT Marquez, L Wei, ...
Communications biology 3 (1), 1-16, 2020
|Activation of HuR downstream of p38 MAPK promotes cardiomyocyte hypertrophy|
S Slone, SR Anthony, X Wu, JB Benoit, J Aube, L Xu, M Tranter
Cellular signalling 28 (11), 1735-1741, 2016
|Human antigen R as a therapeutic target in pathological cardiac hypertrophy|
LC Green, SR Anthony, S Slone, L Lanzillotta, ML Nieman, X Wu, ...
JCI insight 4 (4), 2019
|The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro|
K Kaur, X Wu, JK Fields, DK Johnson, L Lan, M Pratt, AD Somoza, ...
PLoS One 12 (4), e0175471, 2017
|Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins|
L Lan, H Liu, AR Smith, C Appelman, J Yu, S Larsen, RT Marquez, X Wu, ...
BMC cancer 18 (1), 1-14, 2018
|Discovery, bioactivity and docking simulation of Vorinostat analogues containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors and antitumor agents.|
JM Cai J, Wei H, Hong KH, Wu X, Zong X, Cao M, Wang P, Li L, Sun C, Chen B ...
Bioorg Med Chem 23 (13), 3457-3471, 2015
|MicroRNA‐383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression|
J Li, AR Smith, RT Marquez, J Li, K Li, L Lan, X Wu, L Zhao, F Ren, ...
Molecular carcinogenesis 57 (10), 1408-1420, 2018
|Gemcitabine enhances cell invasion via activating HAb18G/CD147-EGFR-pSTAT3 signaling|
BQ Xu, ZG Fu, Y Meng, XQ Wu, B Wu, L Xu, JL Jiang, L Li, ZN Chen
Oncotarget 7 (38), 62177, 2016
|Discovery of phenoxybutanoic acid derivatives as potent endothelin antagonists with antihypertensive activity|
JM Cai J, Liu L, Hong KH, Wang P, Li L, Cao M, Sun C, Wu X, Zong X, Chen J
Bioorg Med Chem 23 (4), 657-667, 2015