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Sofia Benfeito
Sofia Benfeito
PhD
Verified email at fc.up.pt
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Cited by
Cited by
Year
Antioxidant therapy: Still in search of the ‘magic bullet’
S Benfeito, C Oliveira, P Soares, C Fernandes, T Silva, J Teixeira, ...
Mitochondrion 13 (5), 427-435, 2013
762013
NO and HNO donors, nitrones, and nitroxides: Past, present, and future
C Oliveira, S Benfeito, C Fernandes, F Cagide, T Silva, F Borges
Medicinal research reviews 38 (4), 1159-1187, 2018
682018
Exploring nature profits: Development of novel and potent lipophilic antioxidants based on galloyl–cinnamic hybrids
J Teixeira, T Silva, S Benfeito, A Gaspar, EM Garrido, J Garrido, F Borges
European journal of medicinal chemistry 62, 289-296, 2013
622013
Development of a mitochondriotropic antioxidant based on caffeic acid: proof of concept on cellular and mitochondrial oxidative stress models
J Teixeira, F Cagide, S Benfeito, P Soares, J Garrido, I Baldeiras, ...
Journal of medicinal chemistry 60 (16), 7084-7098, 2017
582017
Fine-tuning of the hydrophobicity of caffeic acid: studies on the antimicrobial activity against Staphylococcus aureus and Escherichia coli
M Andrade, S Benfeito, P Soares, DM e Silva, J Loureiro, A Borges, ...
RSC Advances 5 (66), 53915-53925, 2015
562015
Rational discovery and development of a mitochondria-targeted antioxidant based on cinnamic acid scaffold
JÉ Teixeira, P Soares, S Benfeito, A Gaspar, J Garrido, MP Murphy, ...
Free radical research 46 (5), 600-611, 2012
522012
Molecular mechanisms of ferroptosis and their involvement in brain diseases
I Costa, DJ Barbosa, S Benfeito, V Silva, D Chavarria, F Borges, F Remião, ...
Pharmacology & Therapeutics 244, 108373, 2023
502023
Fine-tuning the neuroprotective and blood-brain barrier permeability profile of multi-target agents designed to prevent progressive mitochondrial dysfunction
S Benfeito, C Oliveira, C Fernandes, F Cagide, J Teixeira, R Amorim, ...
European journal of medicinal chemistry 167, 525-545, 2019
372019
Nanotechnology and antioxidant therapy: an emerging approach for neurodegenerative diseases
C Fernandes, C Oliveira, S Benfeito, P Soares, J Garrido, F Borges
Current medicinal chemistry 21 (38), 4311-4327, 2014
222014
Mitochondria-targeted phenolic antioxidants induce ROS-protective pathways in primary human skin fibroblasts
J Teixeira, F Basit, PHGM Willems, JA Wagenaars, E van de Westerlo, ...
Free Radical Biology and Medicine 163, 314-324, 2021
192021
Effects of chlorophenoxy herbicides and their main transformation products on DNA damage and acetylcholinesterase activity
S Benfeito, T Silva, J Garrido, PB Andrade, MJ Sottomayor, F Borges, ...
BioMed Research International 2014, 2014
182014
Mitochondriotropic antioxidant based on caffeic acid AntiOxCIN4 activates Nrf2-dependent antioxidant defenses and quality control mechanisms to antagonize oxidative stress …
R Amorim, F Cagide, LC Tavares, RF Simões, P Soares, S Benfeito, ...
Free Radical Biology and Medicine 179, 119-132, 2022
162022
A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients
CM Deus, SP Pereira, T Cunha-Oliveira, J Teixeira, RF Simões, F Cagide, ...
Redox biology 45, 102037, 2021
152021
Antioxidant therapy, oxidative stress, and blood-brain barrier: the road of dietary antioxidants
M Pinto, S Benfeito, C Fernandes, F Borges
Oxidative stress and dietary antioxidants in neurological diseases, 125-141, 2020
152020
Host-guest interaction between herbicide oxadiargyl and hydroxypropyl-β-cyclodextrin
S Benfeito, T Rodrigues, J Garrido, F Borges, EM Garrido
The Scientific World Journal 2013, 2013
152013
Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation …
R Amorim, ICM Simões, J Teixeira, F Cagide, Y Potes, P Soares, ...
Redox Biology 55, 102400, 2022
132022
Exploring the multi-target performance of mitochondriotropic antioxidants against the pivotal Alzheimer’s disease pathophysiological hallmarks
S Benfeito, C Fernandes, S Vilar, F Remião, E Uriarte, F Borges
Molecules 25 (2), 276, 2020
132020
Desrisking the cytotoxicity of a Mitochondriotropic antioxidant based on Caffeic acid by a PEGylated strategy
C Fernandes, S Benfeito, R Amorim, J Teixeira, PJ Oliveira, F Remiao, ...
Bioconjugate chemistry 29 (8), 2723-2733, 2018
132018
Photodamage and photoprotection: toward safety and sustainability through nanotechnology solutions
C Fernandes, S Benfeito, A Fonseca, C Oliveira, J Garrido, EM Garrido, ...
Food preservation, 527-565, 2017
132017
Boosting drug discovery for Parkinson’s: enhancement of the delivery of a monoamine oxidase-B inhibitor by brain-targeted PEGylated polycaprolactone-based nanoparticles
M Pinto, C Fernandes, E Martins, R Silva, S Benfeito, F Cagide, ...
Pharmaceutics 11 (7), 331, 2019
112019
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