Dr. Michael Lappe, Ph.D.
Dr. Michael Lappe, Ph.D.
Clinical Bioinformatician
Verified email at - Homepage
Cited by
Cited by
Estimating the size of the human interactome
MPH Stumpf, T Thorne, E De Silva, R Stewart, HJ An, M Lappe, C Wiuf
Proceedings of the National Academy of Sciences 105 (19), 6959-6964, 2008
The HUPO PSI's molecular interaction format—a community standard for the representation of protein interaction data
H Hermjakob, L Montecchi-Palazzi, G Bader, J Wojcik, L Salwinski, ...
Nature biotechnology 22 (2), 177-183, 2004
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
D Olagnier, E Farahani, J Thyrsted, J Blay-Cadanet, A Herengt, M Idorn, ...
Nature communications 11 (1), 4938, 2020
Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis
B Timmermann, M Kerick, C Roehr, A Fischer, M Isau, ST Boerno, ...
PloS one 5 (12), e15661, 2010
A fully automatic evolutionary classification of protein folds: Dali Domain Dictionary version 3
S Dietmann, J Park, C Notredame, A Heger, M Lappe, L Holm
Nucleic acids research 29 (1), 55-57, 2001
Mapping protein family interactions: intramolecular and intermolecular protein family interaction repertoires in the PDB and yeast
J Park, M Lappe, SA Teichmann
Journal of molecular biology 307 (3), 929-938, 2001
From gene networks to gene function
T Schlitt, K Palin, J Rung, S Dietmann, M Lappe, E Ukkonen, A Brazma
Genome research 13 (12), 2568-2576, 2003
H3K64 trimethylation marks heterochromatin and is dynamically remodeled during developmental reprogramming
S Daujat, T Weiss, F Mohn, UC Lange, C Ziegler-Birling, U Zeissler, ...
Nature structural & molecular biology 16 (7), 777-781, 2009
CMView: interactive contact map visualization and analysis
C Vehlow, H Stehr, M Winkelmann, JM Duarte, L Petzold, J Dinse, ...
Bioinformatics 27 (11), 1573-1574, 2011
PSIbase: a database of Protein Structural Interactome map (PSIMAP)
S Gong, G Yoon, I Jang, D Bolser, P Dafas, M Schroeder, H Choi, Y Cho, ...
Bioinformatics 21 (10), 2541-2543, 2005
Unraveling protein interaction networks with near-optimal efficiency
M Lappe, L Holm
Nature biotechnology 22 (1), 98-103, 2004
Optimal contact definition for reconstruction of contact maps
JM Duarte, R Sathyapriya, H Stehr, I Filippis, M Lappe
BMC bioinformatics 11, 1-10, 2010
The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors
H Stehr, SHJ Jang, JM Duarte, C Wierling, H Lehrach, M Lappe, ...
Molecular cancer 10, 1-10, 2011
Optimized null model for protein structure networks
T Milenković, I Filippis, M Lappe, N Pržulj
PLoS One 4 (6), e5967, 2009
Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics
A Haupt, G Joberty, M Bantscheff, H Fröhlich, H Stehr, MR Schweiger, ...
BMC cancer 12, 1-12, 2012
Defining an essence of structure determining residue contacts in proteins
R Sathyapriya, JM Duarte, H Stehr, I Filippis, M Lappe
PLoS computational biology 5 (12), e1000584, 2009
Comparative interactomics analysis of protein family interaction networks using PSIMAP (protein structural interactome map)
D Park, S Lee, D Bolser, M Schroeder, M Lappe, D Oh, J Bhak
Bioinformatics 21 (15), 3234-3240, 2005
Crosstalk between phosphorylation and multi-site arginine/lysine methylation in C/EBPs
A Leutz, O Pless, M Lappe, G Dittmar, E Kowenz-Leutz
Transcription 2 (1), 3-8, 2011
Generating protein interaction maps from incomplete data: application to fold assignment
M Lappe, J Park, O Niggemann, L Holm
Bioinformatics 17 (suppl_1), S149-S156, 2001
Accurate detection of very sparse sequence motifs
A Heger, M Lappe, L Holm
Proceedings of the seventh annual international conference on Research in …, 2003
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Articles 1–20