|In silico screening and biological evaluation of inhibitors of Src-SH3 domain interaction with a proline-rich ligand|
N Atatreh, C Stojkoski, P Smith, GW Booker, C Dive, AD Frenkel, ...
Bioorganic & medicinal chemistry letters 18 (3), 1217-1222, 2008
|Effects of antihistamines on the function of human α7-nicotinic acetylcholine receptors|
B Sadek, SS Khanian, A Ashoor, T Prytkova, MA Ghattas, N Atatreh, ...
European journal of pharmacology 746, 308-316, 2015
|Druggability analysis and classification of protein tyrosine phosphatase active sites|
MA Ghattas, N Raslan, A Sadeq, M Al Sorkhy, N Atatreh
Drug design, development and therapy 10, 3197, 2016
|Antibacterial activity and mechanism of action of the benzazole acrylonitrile-based compounds: in vitro, spectroscopic, and docking studies|
SS AlNeyadi, AA Salem, MA Ghattas, N Atatreh, IM Abdou
European Journal of Medicinal Chemistry 136, 270-282, 2017
|Protein tyrosine phosphatases: Ligand interaction analysis and optimisation of virtual screening|
MA Ghattas, N Atatreh, EV Bichenkova, RA Bryce
Journal of Molecular Graphics and Modelling 52, 114-123, 2014
|Analysis of Enoyl‐Acyl carrier protein reductase structure and interactions yields an efficient virtual screening approach and suggests a potential allosteric site|
MA Ghattas, RA Mansour, N Atatreh, RA Bryce
Chemical biology & drug design 87 (1), 131-142, 2016
|Identification of new inhibitors of Mdm2–p53 interaction via pharmacophore and structure-based virtual screening|
N Atatreh, MA Ghattas, SK Bardaweel, S Al Rawashdeh, M Al Sorkhy
Drug design, development and therapy 12, 3741, 2018
|Anti-inflammatory drug approach: Synthesis and biological evaluation of novel pyrazolo [3, 4-d] pyrimidine compounds|
N Atatreh, AM Youssef, MA Ghattas, M Al Sorkhy, S Alrawashdeh, ...
Bioorganic chemistry 86, 393-400, 2019
|Difluoro analogue of UCS15A triggers activation of exogenously expressed c-Src in HCT 116 human colorectal carcinoma cells|
N Atatreh, J Barraclough, A Welman, C Cawthorne, RA Bryce, C Dive, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 22 (5), 638-646, 2007
|Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening|
N Atatreh, S Al Rawashdah, SS Al Neyadi, SM Abuhamdah, MA Ghattas
Journal of enzyme inhibition and medicinal chemistry 34 (1), 1373-1379, 2019
|Comparative molecular dynamics simulation of aggregating and non‐aggregating inhibitor solutions: understanding the molecular basis of promiscuity|
MA Ghattas, RA Bryce, S Al Rawashdah, N Atatreh, WA Zalloum
ChemMedChem 13 (6), 500-506, 2018
|Computer-aided discovery of antimicrobial agents as potential enoyl acyl carrier protein reductase inhibitors|
MA Ghattas, NA Eissa, SK Bardaweel, AA Mellal, N Atatreh
Tropical Journal of Pharmaceutical Research 16 (2), 397-405, 2017
|Design, Synthesis, in Vitro Antibacterial Activity, and Docking Studies of New Rhodanine Derivatives|
A Abusetta, J Alumairi, MY Alkaabi, R Al Ajeil, AA Shkaidim, D Akram, ...
Open Journal of Medicinal Chemistry 10 (1), 15-34, 2020
|Isoindolinone based inhibitors of the MDM2-p53 protein-protein interaction|
SJ Kemp, IR Hardcastle, SU Ahmed, NA Atatreh, P Barrett, JA Endicott, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U2735-U2736, 2005
|How Do Small Molecule Aggregates Inhibit Enzyme Activity? A Molecular Dynamics Study|
MA Ghattas, S Al-Rawashdah, N Atatreh, RA Bryce
Journal of Chemical Information and Modeling, 2020
|Anti-Cancer Activity and Molecular Docking of Some Pyrano [3, 2‑c] quinoline Analogues|
AM Saeed, IM Abdou, AA Salem, MA Ghattas, N Atatreh, SS AlNeyadi
Open Journal of Medicinal Chemistry 10 (1), 1-14, 2020
|Molecular modelling studies on ɑ7 nicotinic receptor allosteric modulators yields novel filter-based virtual screening protocol|
S Al Rawashdah, A Hamrouni, B Sadek, R Amer, M Metwaly, N Atatreh, ...
Journal of Molecular Graphics and Modelling 92, 44-54, 2019
|Structure‐based drug design and in vitro testing reveal new inhibitors of enoyl‐acyl carrier protein reductases|
MA Ghattas, NA Eissa, F Tessaro, R Perozzo, L Scapozza, D Obaid, ...
Chemical biology & drug design 94 (2), 1545-1555, 2019
|Enzyme adsorption by drug aggregates: probing the molecular basis of inhibitor promiscuity using molecular dynamics simulations|
M Ghattas, N Atatreh, S Alrawashdeh, R Bryce
EUROPEAN JOURNAL OF CANCER 103, E68-E69, 2018
|The discovery of potential CDK2-Spy1 inhibitors via structure-based drug design|
N Atatreh, M Al Sorkhy, S Al Rawashdah, M Ghattas
EUROPEAN JOURNAL OF CANCER 103, E93-E94, 2018