Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1905* | 2020 |
The evolutionary history of 2,658 cancers M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ... Nature 578 (7793), 122-128, 2020 | 970 | 2020 |
PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors AG Deshwar, S Vembu, CK Yung, GH Jang, L Stein, Q Morris Genome biology 16, 1-20, 2015 | 454 | 2015 |
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell 184 (8), 2239-2254. e39, 2021 | 351 | 2021 |
Inferring clonal evolution of tumors from single nucleotide somatic mutations W Jiao, S Vembu, AG Deshwar, L Stein, Q Morris BMC bioinformatics 15, 1-16, 2014 | 279 | 2014 |
A practical guide to cancer subclonal reconstruction from DNA sequencing M Tarabichi, A Salcedo, AG Deshwar, M Ni Leathlobhair, J Wintersinger, ... Nature methods 18 (2), 144-155, 2021 | 146 | 2021 |
Computational purification of individual tumor gene expression profiles leads to significant improvements in prognostic prediction G Quon, S Haider, AG Deshwar, A Cui, PC Boutros, Q Morris Genome medicine 5, 1-20, 2013 | 109 | 2013 |
Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism DU Kemaladewi, E Maino, E Hyatt, H Hou, M Ding, KM Place, X Zhu, ... Nature medicine 23 (8), 984-989, 2017 | 94 | 2017 |
A community effort to create standards for evaluating tumor subclonal reconstruction A Salcedo, M Tarabichi, SMG Espiritu, AG Deshwar, M David, NM Wilson, ... Nature biotechnology 38 (1), 97-107, 2020 | 71 | 2020 |
COSSMO: predicting competitive alternative splice site selection using deep learning H Bretschneider, S Gandhi, AG Deshwar, K Zuberi, BJ Frey Bioinformatics 34 (13), i429-i437, 2018 | 60 | 2018 |
Transcriptome-wide off-target effects of steric-blocking oligonucleotides EM Holgersen, S Gandhi, Y Zhou, J Kim, B Vaz, J Bogojeski, M Bugno, ... nucleic acid therapeutics 31 (6), 392-403, 2021 | 58 | 2021 |
Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig Y Rubanova, R Shi, CF Harrigan, R Li, J Wintersinger, N Sahin, ... Nature communications 11 (1), 731, 2020 | 48 | 2020 |
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples MH Bailey, WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, ... Nature communications 11 (1), 4748, 2020 | 44 | 2020 |
Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... BioRxiv, 312041, 2018 | 43 | 2018 |
ISOpureR: an R implementation of a computational purification algorithm of mixed tumour profiles CV Anghel, G Quon, S Haider, F Nguyen, AG Deshwar, QD Morris, ... BMC bioinformatics 16, 1-11, 2015 | 40 | 2015 |
PCAWG Evolution and Heterogeneity Working Group and the PCAWG Consortium. Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes SC Dentro, I Leshchiner, K Haase, M Tarabichi, J Wintersinger, ... Cell 184 (8), 2239-54, 2021 | 30 | 2021 |
PLIDA: cross-platform gene expression normalization using perturbed topic models AG Deshwar, Q Morris Bioinformatics 30 (7), 956-961, 2014 | 24 | 2014 |
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics A Celaj, AJ Gao, TTY Lau, EM Holgersen, A Lo, V Lodaya, CB Cole, ... bioRxiv, 2023.09. 20.558508, 2023 | 19 | 2023 |
Identifying cancer specific functionally relevant miRNAs from gene expression and miRNA-to-gene networks using regularized regression AM Mezlini, B Wang, A Deshwar, Q Morris, A Goldenberg PloS one 8 (10), e73168, 2013 | 17 | 2013 |
ATP7B variant c.1934T > G p.Met645Arg causes Wilson disease by promoting exon 6 skipping D Merico, C Spickett, M O’Hara, B Kakaradov, AG Deshwar, P Fradkin, ... NPJ genomic medicine 5 (1), 16, 2020 | 13 | 2020 |