Nicholas Schaum
Nicholas Schaum
University of Cambridge
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Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris.
TM Consortium
Nature 562 (7727), 367, 2018
A single-cell transcriptomic atlas characterizes ageing tissues in the mouse
Nature 583 (7817), 590-595, 2020
Undulating changes in human plasma proteome profiles across the lifespan
B Lehallier, D Gate, N Schaum, T Nanasi, SE Lee, H Yousef, ...
Nature medicine 25 (12), 1843-1850, 2019
Dysregulation of brain and choroid plexus cell types in severe COVID-19
AC Yang, F Kern, PM Losada, MR Agam, CA Maat, GP Schmartz, ...
Nature 595 (7868), 565-571, 2021
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans
The Tabula Sapiens Consortium*, RC Jones, J Karkanias, MA Krasnow, ...
Science 376 (6594), eabl4896, 2022
p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
AR Davalos, M Kawahara, GK Malhotra, N Schaum, J Huang, U Ved, ...
Journal of Cell Biology 201 (4), 613-629, 2013
Ageing hallmarks exhibit organ-specific temporal signatures
N Schaum, B Lehallier, O Hahn, R Pálovics, S Hosseinzadeh, SE Lee, ...
Nature 583 (7817), 596-602, 2020
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk
AC Yang, RT Vest, F Kern, DP Lee, M Agam, CA Maat, PM Losada, ...
Nature 603 (7903), 885-892, 2022
Brain endothelial cells are exquisite sensors of age-related circulatory cues
MB Chen, AC Yang, H Yousef, D Lee, W Chen, N Schaum, B Lehallier, ...
Cell reports 30 (13), 4418-4432. e4, 2020
Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype
CD Wiley, N Schaum, F Alimirah, JA Lopez-Dominguez, AV Orjalo, ...
Scientific reports 8 (1), 2410, 2018
miRNATissueAtlas2: an update to the human miRNA tissue atlas
A Keller, L Gröger, T Tschernig, J Solomon, O Laham, N Schaum, ...
Nucleic acids research 50 (D1), D211-D221, 2022
Molecular hallmarks of heterochronic parabiosis at single-cell resolution
R Pálovics, A Keller, N Schaum, W Tan, T Fehlmann, M Borja, F Kern, ...
Nature 603 (7900), 309-314, 2022
Common diseases alter the physiological age-related blood microRNA profile
T Fehlmann, B Lehallier, N Schaum, O Hahn, M Kahraman, Y Li, ...
Nature communications 11 (1), 5958, 2020
Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain
MT Buckley, ED Sun, BM George, L Liu, N Schaum, L Xu, JM Reyes, ...
Nature Aging 3 (1), 121-137, 2023
Simulations of monomeric amyloid β-peptide (1–40) with varying solution conditions and oxidation state of Met35: Implications for aggregation
AM Brown, JA Lemkul, N Schaum, DR Bevan
Archives of biochemistry and biophysics 545, 44-52, 2014
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
MS Haney, R Pálovics, CN Munson, C Long, PK Johansson, O Yip, ...
Nature 628 (8006), 154-161, 2024
Characterizing expression changes in noncoding RNAs during aging and heterochronic parabiosis across mouse tissues
V Wagner, F Kern, O Hahn, N Schaum, N Ludwig, T Fehlmann, A Engel, ...
Nature Biotechnology 42 (1), 109-118, 2024
APOE4/4 is linked to damaging lipid droplets in Alzheimer’s microglia
MS Haney, R Palovics, CN Munson, C Long, P Johansson, O Yip, ...
bioRxiv, 2023
Broad transcriptional dysregulation of brain and choroid plexus cell types with COVID-19 (preprint)
AC Yang, F Kern, PM Losada, CA Maat, G Schmartz, T Fehlmann, ...
Characterizing Mouse Aging Organism-wide with RNA-Sequencing and Single-cell RNA-Sequencing
ND Schaum
Stanford University, 2019
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