Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material B De Backer, B Debrus, P Lebrun, L Theunis, N Dubois, L Decock, ... Journal of Chromatography B 877 (32), 4115-4124, 2009 | 364 | 2009 |
Design spaces for analytical methods E Rozet, P Lebrun, P Hubert, B Debrus, B Boulanger TrAC Trends in Analytical Chemistry 42, 157-167, 2013 | 286 | 2013 |
Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach F Mehl, G Marti, J Boccard, B Debrus, P Merle, E Delort, L Baroux, ... Food chemistry 143, 325-335, 2014 | 139 | 2014 |
Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments … B Debrus, P Lebrun, JM Kindenge, F Lecomte, A Ceccato, G Caliaro, ... Journal of Chromatography A 1218 (31), 5205-5215, 2011 | 116 | 2011 |
Development of a new predictive modelling technique to find with confidence equivalence zone and design space of chromatographic analytical methods P Lebrun, B Govaerts, B Debrus, A Ceccato, G Caliaro, P Hubert, ... Chemometrics and Intelligent Laboratory Systems 91 (1), 4-16, 2008 | 116 | 2008 |
Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography B Debrus, D Guillarme, S Rudaz Journal of pharmaceutical and biomedical analysis 84, 215-223, 2013 | 114 | 2013 |
Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography B Debrus, P Lebrun, A Ceccato, G Caliaro, E Rozet, I Nistor, R Oprean, ... Analytica Chimica Acta 691 (1-2), 33-42, 2011 | 103 | 2011 |
Screening of the most relevant parameters for method development in ultra-high performance hydrophilic interaction chromatography A Periat, B Debrus, S Rudaz, D Guillarme Journal of Chromatography A 1282, 72-83, 2013 | 95 | 2013 |
Evaluation of cannabinoid and terpenoid content: cannabis flower compared to supercritical CO2 concentrate M Sexton, K Shelton, P Haley, M West Planta medica 84 (04), 234-241, 2018 | 70 | 2018 |
Retention time prediction for dereplication of natural products (CxHyOz) in LC–MS metabolite profiling PJ Eugster, J Boccard, B Debrus, L Bréant, JL Wolfender, S Martel, ... Phytochemistry 108, 196-207, 2014 | 66 | 2014 |
Determination of acid and neutral cannabinoids in extracts of different strains of Cannabis sativa using GC-FID EA Ibrahim, W Gul, SW Gul, BJ Stamper, GM Hadad, RAA Salam, ... Planta Medica 84 (04), 250-259, 2018 | 63 | 2018 |
Quantitative determination of Δ9-THC, CBG, CBD, their acid precursors and five other neutral cannabinoids by UHPLC-UV-MS YH Wang, B Avula, MA ElSohly, MM Radwan, M Wang, AS Wanas, ... Planta Medica 84 (04), 260-266, 2018 | 61 | 2018 |
Rational and efficient preparative isolation of natural products by MPLC-UV-ELSD based on HPLC to MPLC gradient transfer S Challal, EF Queiroz, B Debrus, W Kloeti, D Guillarme, MP Gupta, ... Planta medica 81 (17), 1636-1643, 2015 | 54 | 2015 |
Application of an innovative design space optimization strategy to the development of liquid chromatographic methods to combat potentially counterfeit nonsteroidal anti … JK Mbinze, P Lebrun, B Debrus, A Dispas, N Kalenda, JMT Mbay, ... Journal of Chromatography A 1263, 113-124, 2012 | 50 | 2012 |
Development of a nano-liquid chromatography on chip tandem mass spectrometry method for high-sensitivity hepcidin quantitation V Houbart, G Cobraiville, F Lecomte, B Debrus, P Hubert, M Fillet Journal of Chromatography a 1218 (50), 9046-9054, 2011 | 45 | 2011 |
Validation, transfer and measurement uncertainty estimation of an HPLC–UV method for the quantification of artemisinin in hydro alcoholic extracts of Artemisia annua L. HZ Diawara, F Gbaguidi, B Evrard, JQ Leclercq, M Moudachirou, ... Journal of pharmaceutical and biomedical analysis 56 (1), 7-15, 2011 | 45 | 2011 |
Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities F Krier, M Brion, B Debrus, P Lebrun, A Driesen, E Ziemons, B Evrard, ... Journal of pharmaceutical and biomedical analysis 54 (4), 694-700, 2011 | 44 | 2011 |
A Bayesian design space for analytical methods based on multivariate models and predictions P Lebrun, B Boulanger, B Debrus, P Lambert, P Hubert Journal of biopharmaceutical statistics 23 (6), 1330-1351, 2013 | 40 | 2013 |
Predictive elution window stretching and shifting as a generic search strategy for automated method development for liquid chromatography E Tyteca, A Liekens, D Clicq, A Fanigliulo, B Debrus, S Rudaz, ... Analytical chemistry 84 (18), 7823-7830, 2012 | 37 | 2012 |
Application of design of experiments and design space methodology for the HPLC-UV separation optimization of aporphine alkaloids from leaves of Spirospermum penduliflorum Thouars MH Rafamantanana, B Debrus, GE Raoelison, E Rozet, P Lebrun, ... Journal of pharmaceutical and biomedical analysis 62, 23-32, 2012 | 37 | 2012 |