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Benjamin Debrus
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Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant material
B De Backer, B Debrus, P Lebrun, L Theunis, N Dubois, L Decock, ...
Journal of Chromatography B 877 (32), 4115-4124, 2009
3452009
Design spaces for analytical methods
E Rozet, P Lebrun, P Hubert, B Debrus, B Boulanger
TrAC Trends in Analytical Chemistry 42, 157-167, 2013
2732013
Differentiation of lemon essential oil based on volatile and non-volatile fractions with various analytical techniques: a metabolomic approach
F Mehl, G Marti, J Boccard, B Debrus, P Merle, E Delort, L Baroux, ...
Food chemistry 143, 325-335, 2014
1282014
Development of a new predictive modelling technique to find with confidence equivalence zone and design space of chromatographic analytical methods
P Lebrun, B Govaerts, B Debrus, A Ceccato, G Caliaro, P Hubert, ...
Chemometrics and Intelligent Laboratory Systems 91 (1), 4-16, 2008
1152008
Innovative high-performance liquid chromatography method development for the screening of 19 antimalarial drugs based on a generic approach, using design of experiments …
B Debrus, P Lebrun, JM Kindenge, F Lecomte, A Ceccato, G Caliaro, ...
Journal of Chromatography A 1218 (31), 5205-5215, 2011
1122011
Improved quality-by-design compliant methodology for method development in reversed-phase liquid chromatography
B Debrus, D Guillarme, S Rudaz
Journal of pharmaceutical and biomedical analysis 84, 215-223, 2013
1072013
Application of new methodologies based on design of experiments, independent component analysis and design space for robust optimization in liquid chromatography
B Debrus, P Lebrun, A Ceccato, G Caliaro, E Rozet, I Nistor, R Oprean, ...
Analytica Chimica Acta 691 (1-2), 33-42, 2011
1012011
Screening of the most relevant parameters for method development in ultra-high performance hydrophilic interaction chromatography
A Periat, B Debrus, S Rudaz, D Guillarme
Journal of Chromatography A 1282, 72-83, 2013
942013
Evaluation of cannabinoid and terpenoid content: cannabis flower compared to supercritical CO2 concentrate
M Sexton, K Shelton, P Haley, M West
Planta medica 84 (04), 234-241, 2018
652018
Retention time prediction for dereplication of natural products (CxHyOz) in LC–MS metabolite profiling
PJ Eugster, J Boccard, B Debrus, L Bréant, JL Wolfender, S Martel, ...
Phytochemistry 108, 196-207, 2014
622014
Determination of acid and neutral cannabinoids in extracts of different strains of Cannabis sativa using GC-FID
EA Ibrahim, W Gul, SW Gul, BJ Stamper, GM Hadad, RAA Salam, ...
Planta Medica 84 (04), 250-259, 2018
612018
Quantitative determination of Δ9-THC, CBG, CBD, their acid precursors and five other neutral cannabinoids by UHPLC-UV-MS
YH Wang, B Avula, MA ElSohly, MM Radwan, M Wang, AS Wanas, ...
Planta Medica 84 (04), 260-266, 2018
562018
Rational and efficient preparative isolation of natural products by MPLC-UV-ELSD based on HPLC to MPLC gradient transfer
S Challal, EF Queiroz, B Debrus, W Kloeti, D Guillarme, MP Gupta, ...
Planta medica 81 (17), 1636-1643, 2015
512015
Application of an innovative design space optimization strategy to the development of liquid chromatographic methods to combat potentially counterfeit nonsteroidal anti …
JK Mbinze, P Lebrun, B Debrus, A Dispas, N Kalenda, JMT Mbay, ...
Journal of Chromatography A 1263, 113-124, 2012
492012
Development of a nano-liquid chromatography on chip tandem mass spectrometry method for high-sensitivity hepcidin quantitation
V Houbart, G Cobraiville, F Lecomte, B Debrus, P Hubert, M Fillet
Journal of Chromatography a 1218 (50), 9046-9054, 2011
452011
Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities
F Krier, M Brion, B Debrus, P Lebrun, A Driesen, E Ziemons, B Evrard, ...
Journal of pharmaceutical and biomedical analysis 54 (4), 694-700, 2011
442011
Validation, transfer and measurement uncertainty estimation of an HPLC–UV method for the quantification of artemisinin in hydro alcoholic extracts of Artemisia annua L.
HZ Diawara, F Gbaguidi, B Evrard, JQ Leclercq, M Moudachirou, ...
Journal of pharmaceutical and biomedical analysis 56 (1), 7-15, 2011
412011
A Bayesian design space for analytical methods based on multivariate models and predictions
P Lebrun, B Boulanger, B Debrus, P Lambert, P Hubert
Journal of biopharmaceutical statistics 23 (6), 1330-1351, 2013
382013
Application of design of experiments and design space methodology for the HPLC-UV separation optimization of aporphine alkaloids from leaves of Spirospermum penduliflorum Thouars
MH Rafamantanana, B Debrus, GE Raoelison, E Rozet, P Lebrun, ...
Journal of pharmaceutical and biomedical analysis 62, 23-32, 2012
362012
A new statistical method for the automated detection of peaks in UV-DAD chromatograms of a sample mixture
B Debrus, P Lebrun, A Ceccato, G Caliaro, B Govaerts, BA Olsen, E Rozet, ...
Talanta 79 (1), 77-85, 2009
352009
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