Boris Novakovic
Boris Novakovic
Murdoch Children's Research Institute, Associate Professor, University of Melbourne
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BCG vaccination protects against experimental viral infection in humans through the induction of cytokines associated with trained immunity
RJW Arts, SJ Moorlag, B Novakovic, Y Li, SY Wang, M Oosting, V Kumar, ...
Cell host & microbe 23 (1), 89-100. e5, 2018
Glutaminolysis and fumarate accumulation integrate immunometabolic and epigenetic programs in trained immunity
RJW Arts, B Novakovic, R Ter Horst, A Carvalho, S Bekkering, ...
Cell metabolism 24 (6), 807-819, 2016
Metabolic induction of trained immunity through the mevalonate pathway
S Bekkering, RJW Arts, B Novakovic, I Kourtzelis, CDCC van der Heijden, ...
Cell 172 (1), 135-146. e9, 2018
β-Glucan reverses the epigenetic state of LPS-induced immunological tolerance
B Novakovic, E Habibi, SY Wang, RJW Arts, R Davar, W Megchelenbrink, ...
Cell 167 (5), 1354-1368. e14, 2016
Trained immunity, tolerance, priming and differentiation: distinct immunological processes
M Divangahi, P Aaby, SA Khader, LB Barreiro, S Bekkering, T Chavakis, ...
Nature immunology 22 (1), 2-6, 2021
DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome
M Ollikainen, KR Smith, EJH Joo, HK Ng, R Andronikos, B Novakovic, ...
Human molecular genetics 19 (21), 4176-4188, 2010
Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface
B Novakovic, M Sibson, HK Ng, U Manuelpillai, V Rakyan, T Down, ...
Journal of Biological Chemistry 284 (22), 14838-14848, 2009
Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence
L Gordon, JE Joo, JE Powell, M Ollikainen, B Novakovic, X Li, ...
Genome research 22 (8), 1395-1406, 2012
The itaconate pathway is a central regulatory node linking innate immune tolerance and trained immunity
J Domínguez-Andrés, B Novakovic, Y Li, BP Scicluna, MS Gresnigt, ...
Cell metabolism 29 (1), 211-220. e5, 2019
Intrauterine programming of obesity and type 2 diabetes
DS Fernandez-Twinn, L Hjort, B Novakovic, SE Ozanne, R Saffery
Diabetologia 62, 1789-1801, 2019
Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors
B Novakovic, RK Yuen, L Gordon, MS Penaherrera, A Sharkey, A Moffett, ...
BMC genomics 12, 1-14, 2011
BCG vaccination induces long-term functional reprogramming of human neutrophils
SJ Moorlag, YA Rodriguez-Rosales, J Gillard, S Fanucchi, K Theunissen, ...
Cell reports 33 (7), 2020
β-Glucan induces protective trained immunity against Mycobacterium tuberculosis infection: a key role for IL-1
SJ Moorlag, N Khan, B Novakovic, E Kaufmann, T Jansen, R van Crevel, ...
Cell reports 31 (7), 2020
Sexual dimorphism in innate immunity: the role of sex hormones and epigenetics
R Shepherd, AS Cheung, K Pang, R Saffery, B Novakovic
Frontiers in immunology 11, 604000, 2021
Uric acid priming in human monocytes is driven by the AKT–PRAS40 autophagy pathway
TO Crişan, MCP Cleophas, B Novakovic, K Erler, FL van de Veerdonk, ...
Proceedings of the National Academy of Sciences 114 (21), 5485-5490, 2017
Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy
B Novakovic, J Ryan, N Pereira, B Boughton, JM Craig, R Saffery
Epigenetics 9 (3), 377-386, 2014
The ever growing complexity of placental epigenetics–role in adverse pregnancy outcomes and fetal programming
B Novakovic, R Saffery
Placenta 33 (12), 959-970, 2012
Epigenetic regulation of human placental function and pregnancy outcome: considerations for causal inference
V Januar, G Desoye, B Novakovic, S Cvitic, R Saffery
American journal of obstetrics and gynecology 213 (4), S182-S196, 2015
Assisted reproductive technologies are associated with limited epigenetic variation at birth that largely resolves by adulthood
B Novakovic, S Lewis, J Halliday, J Kennedy, DP Burgner, A Czajko, ...
Nature Communications 10 (1), 3922, 2019
Treatment with statins does not revert trained immunity in patients with familial hypercholesterolemia
S Bekkering, LCA Stiekema, SB Moens, SL Verweij, B Novakovic, ...
Cell metabolism 30 (1), 1-2, 2019
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