Follow
Woo Shik Shin
Woo Shik Shin
Assistant Professor of Pharmaceutical Sciences, Northeast Ohio Medical University
Verified email at neomed.edu
Title
Cited by
Cited by
Year
Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel
B Li, P Ge, KA Murray, P Sheth, M Zhang, G Nair, MR Sawaya, WS Shin, ...
Nature communications 9 (1), 3609, 2018
5422018
Structural basis for reversible amyloids of hnRNPA1 elucidates their role in stress granule assembly
X Gui, F Luo, Y Li, H Zhou, Z Qin, Z Liu, J Gu, M Xie, K Zhao, B Dai, ...
Nature communications 10 (1), 2006, 2019
1682019
Amyloid β-protein oligomers promote the uptake of tau fibril seeds potentiating intracellular tau aggregation
WS Shin, J Di, Q Cao, B Li, PM Seidler, KA Murray, G Bitan, L Jiang
Alzheimer's research & therapy 11, 1-13, 2019
892019
Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design.
JL Cao Q, Shin WS, Chan H, Vuong CK, Dubois B, Li B, Murray KA, Sawaya MR ...
Natature Chemistry 10 (s41557-018-0147-z), 2018
61*2018
Thymidylate kinase: an old topic brings new perspectives
Q Cui, W S Shin, Y Luo, J Tian, H Cui, D Yin
Current Medicinal Chemistry 20 (10), 1286-1305, 2013
482013
Anti-inflammatory effect of avenanthramides via NF-κB pathways in C2C12 skeletal muscle cells
C Kang, WS Shin, D Yeo, W Lim, T Zhang, LL Ji
Free Radical Biology and Medicine 117, 30-36, 2018
442018
Discovery of 1-hydroxypyridine-2-thiones as selective histone deacetylase inhibitors and their potential application for treating leukemia
R Muthyala, WS Shin, J Xie, YY Sham
Bioorganic & medicinal chemistry letters 25 (19), 4320-4324, 2015
342015
Ischemic axonal injury up-regulates MARK4 in cortical neurons and primes tau phosphorylation and aggregation
EY Hayden, J Putman, S Nunez, WS Shin, M Oberoi, M Charreton, ...
Acta neuropathologica communications 7, 1-12, 2019
242019
Discovery of 1‐Hydroxypyridine‐2(1H)‐thione‐6‐carboxylic Acid as a First‐in‐Class Low‐Cytotoxic Nanomolar Metallo β‐Lactamase Inhibitor
WS Shin, A Bergstrom, RA Bonomo, MW Crowder, R Muthyala, YY Sham
ChemMedChem 12 (11), 845-849, 2017
232017
Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau
X Ma, Y Zhu, J Lu, J Xie, C Li, WS Shin, J Qiang, J Liu, S Dou, Y Xiao, ...
elife 9, e51859, 2020
202020
Different amyloid-β self-assemblies have distinct effects on intracellular tau aggregation
WS Shin, J Di, KA Murray, C Sun, B Li, G Bitan, L Jiang
Frontiers in molecular neuroscience 12, 2019
202019
Cell permeable vanX inhibitors as vancomycin re-sensitizing agents
R Muthyala, N Rastogi, WS Shin, ML Peterson, YY Sham
Bioorganic & medicinal chemistry letters 24 (11), 2535-2538, 2014
182014
CryoEM reveals how the small molecule EGCG binds to Alzheimer’s brain-derived tau fibrils and initiates fibril disaggregation
PM Seidler, DR Boyer, MR Sawaya, P Ge, WS Shin, MA DeTure, ...
bioRxiv, 2020.05. 29.124537, 2020
142020
A novel drug discovery strategy: Mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways
C Zhuang, C Sheng, WS Shin, Y Wu, J Li, J Yao, G Dong, W Zhang, ...
Oncotarget 5 (21), 10830, 2014
122014
Cryo-EM of full-length α-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun 9: 3609
B Li, P Ge, KA Murray, P Sheth, M Zhang, G Nair, MR Sawaya, WS Shin, ...
112018
Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation reveals a distinct protofilament interface
C Sun, K Zhou, P DePaola, WS Shin, T Hillyer, MR Sawaya, R Zhu, ...
Journal of Biological Chemistry 299 (4), 2023
92023
Fragment‐based screening and hit‐based substructure search: Rapid discovery of 8‐hydroxyquinoline‐7‐carboxylic acid as a low‐cytotoxic, nanomolar metallo β‐lactamase inhibitor
WS Shin, ME Nguyen, A Bergstrom, IR Jennings, MW Crowder, ...
Chemical Biology & Drug Design 98 (4), 481-492, 2021
42021
Data on the mode of binding between avenanthramides and IKKβ domains in a docking model
C Kang, WS Shin, D Yeo, W Lim, LL Ji
Data in brief 17, 994-997, 2018
42018
Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9 (1), 3609
B Li, P Ge, KA Murray, P Sheth, M Zhang, G Nair, MR Sawaya, WS Shin, ...
42018
A novel strategy to characterize the pattern of β-lactam antibiotic-induced drug resistance in Acinetobacter baumannii
T Hillyer, BM Benin, C Sun, N Aguirre, B Willard, YY Sham, WS Shin
Scientific reports 13 (1), 9177, 2023
22023
The system can't perform the operation now. Try again later.
Articles 1–20