Follow
WEI QI
WEI QI
university of virginia, chemical engineering
Verified email at virginia.edu
Title
Cited by
Cited by
Year
Concomitant Raman spectroscopy and dynamic light scattering for characterization of therapeutic proteins at high concentrations
C Zhou, W Qi, EN Lewis, JF Carpenter
Analytical biochemistry 472, 7-20, 2015
1122015
The effects of excipients on protein aggregation during agitation: an interfacial shear rheology study
L Liu, W Qi, DK Schwartz, TW Randolph, JF Carpenter
Journal of pharmaceutical sciences 102 (8), 2460-2470, 2013
1092013
How well do low-and high-concentration protein interactions predict solution viscosities of monoclonal antibodies?
MA Woldeyes, W Qi, VI Razinkov, EM Furst, CJ Roberts
Journal of pharmaceutical sciences 108 (1), 142-154, 2019
802019
A safe, blood-brain barrier permeable triphenylmethane dye inhibits amyloid-β neurotoxicity by generating nontoxic aggregates
HE Wong, W Qi, HM Choi, EJ Fernandez, I Kwon
ACS chemical neuroscience 2 (11), 645-657, 2011
742011
Structural differences between Aβ (1-40) intermediate oligomers and fibrils elucidated by proteolytic fragmentation and hydrogen/deuterium exchange
A Zhang, W Qi, TA Good, EJ Fernandez
Biophysical journal 96 (3), 1091-1104, 2009
682009
Microparticles and nanoparticles delivered in intravenous saline and in an intravenous solution of a therapeutic antibody product
NN Pardeshi, W Qi, K Dahl, L Caplan, JF Carpenter
Journal of pharmaceutical sciences 106 (2), 511-520, 2017
632017
Combined dynamic light scattering and Raman spectroscopy approach for characterizing the aggregation of therapeutic proteins
EN Lewis, W Qi, LH Kidder, S Amin, SM Kenyon, S Blake
Molecules 19 (12), 20888-20905, 2014
552014
A new approach to explore the impact of freeze-thaw cycling on protein structure: hydrogen/deuterium exchange mass spectrometry (HX-MS)
A Zhang, W Qi, SK Singh, EJ Fernandez
Pharmaceutical research 28, 1179-1193, 2011
532011
Two Disaccharides and Trimethylamine N-Oxide Affect Aβ Aggregation Differently, but All Attenuate Oligomer-Induced Membrane Permeability
W Qi, A Zhang, TA Good, EJ Fernandez
Biochemistry 48 (37), 8908-8919, 2009
532009
Osmolyte effects on monoclonal antibody stability and concentration-dependent protein interactions with water and common osmolytes
GV Barnett, VI Razinkov, BA Kerwin, S Blake, W Qi, RA Curtis, CJ Roberts
The Journal of Physical Chemistry B 120 (13), 3318-3330, 2016
512016
Aggregate structure, morphology and the effect of aggregation mechanisms on viscosity at elevated protein concentrations
GV Barnett, W Qi, S Amin, EN Lewis, CJ Roberts
Biophysical Chemistry 207, 21-29, 2015
432015
Characterization of sizes of aggregates of insulin analogs and the conformations of the constituent protein molecules: a concomitant dynamic light scattering and Raman …
C Zhou, W Qi, EN Lewis, JF Carpenter
Journal of Pharmaceutical Sciences 105 (2), 551-558, 2016
412016
Temperature dependence of protein solution viscosity and protein–protein interactions: insights into the origins of high-viscosity protein solutions
MA Woldeyes, W Qi, VI Razinkov, EM Furst, CJ Roberts
Molecular pharmaceutics 17 (12), 4473-4482, 2020
402020
Simultaneous monitoring of peptide aggregate distributions, structure, and kinetics using amide hydrogen exchange: Application to Aβ (1‐40) fibrillogenesis
W Qi, A Zhang, D Patel, S Lee, JL Harrington, L Zhao, D Schaefer, ...
Biotechnology and bioengineering 100 (6), 1214-1227, 2008
402008
Characterization of nanoparticle tracking analysis for quantification and sizing of submicron particles of therapeutic proteins
C Zhou, AB Krueger, JG Barnard, W Qi, JF Carpenter
Journal of Pharmaceutical Sciences 104 (8), 2441-2450, 2015
372015
Effects of Excipients on the Chemical and Physical Stability of Glucagon during Freeze-Drying and Storage in Dried Formulations
WJ Fang, W Qi, J Kinzell, S Prestrelski, JF Carpenter
Pharmaceutical Research, 1-14, 2012
362012
Formation of stable nanobubbles on reconstituting lyophilized formulations containing trehalose
C Zhou, D Cleland, J Snell, W Qi, TW Randolph, JF Carpenter
Journal of Pharmaceutical Sciences 105 (7), 2249-2253, 2016
342016
Structural changes and aggregation mechanisms for anti-streptavidin IgG1 at elevated concentration
GV Barnett, W Qi, S Amin, EN Lewis, VI Razinkov, BA Kerwin, Y Liu, ...
The Journal of Physical Chemistry B 119 (49), 15150-15163, 2015
302015
Kinetics and competing mechanisms of antibody aggregation via bulk-and surface-mediated pathways
CV Wood, S McEvoy, VI Razinkov, W Qi, EM Furst, CJ Roberts
Journal of pharmaceutical sciences 109 (4), 1449-1459, 2020
282020
Membrane interactions of a self-assembling model peptide that mimics the self-association, structure and toxicity of Aβ (1–40)
LC Salay, W Qi, B Keshet, LK Tamm, EJ Fernandez
Biochimica et Biophysica Acta (BBA)-Biomembranes 1788 (9), 1714-1721, 2009
242009
The system can't perform the operation now. Try again later.
Articles 1–20