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toshiro niki
toshiro niki
Verified email at med.kagawa-u.ac.jp
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Year
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
M Seki, S Oomizu, K Sakata, A Sakata, T Arikawa, K Watanabe, K Ito, ...
Clinical immunology 127 (1), 78-88, 2008
5052008
Blood diffusion and Th1-suppressive effects of galectin-9–containing exosomes released by Epstein-Barr virus–infected nasopharyngeal carcinoma cells
J Klibi, T Niki, A Riedel, C Pioche-Durieu, S Souquere, E Rubinstein, ...
Blood, The Journal of the American Society of Hematology 113 (9), 1957-1966, 2009
4872009
Tim-3 is an inducible human natural killer cell receptor that enhances interferon gamma production in response to galectin-9
MK Gleason, TR Lenvik, V McCullar, M Felices, MS O'Brien, SA Cooley, ...
Blood, the Journal of the American Society of Hematology 119 (13), 3064-3072, 2012
3742012
IL-12 upregulates TIM-3 expression and induces T cell exhaustion in patients with follicular B cell non-Hodgkin lymphoma
ZZ Yang, DM Grote, SC Ziesmer, T Niki, M Hirashima, AJ Novak, ...
The Journal of clinical investigation 122 (4), 1271-1282, 2012
3272012
Galectin-9 increases Tim-3+ dendritic cells and CD8+ T cells and enhances antitumor immunity via galectin-9-Tim-3 interactions
K Nagahara, T Arikawa, S Oomizu, K Kontani, A Nobumoto, H Tateno, ...
The Journal of Immunology 181 (11), 7660-7669, 2008
2532008
Discovery of novel and selective IKK-β serine-threonine protein kinase inhibitors. Part 1
T Murata, M Shimada, S Sakakibara, T Yoshino, H Kadono, T Masuda, ...
Bioorganic & medicinal chemistry letters 13 (5), 913-918, 2003
2352003
A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection
JA Mengshol, L Golden-Mason, T Arikawa, M Smith, T Niki, R McWilliams, ...
PloS one 5 (3), e9504, 2010
2202010
Effect of nasopharyngeal carcinoma-derived exosomes on human regulatory T cells
D Mrizak, N Martin, C Barjon, AS Jimenez-Pailhes, R Mustapha, T Niki, ...
Journal of the National Cancer Institute 107 (1), dju363, 2015
2082015
A selective novel low-molecular-weight inhibitor of IκB kinase-β (IKK-β) prevents pulmonary inflammation and shows broad anti-inflammatory activity
K Ziegelbauer, F Gantner, NW Lukacs, A Berlin, K Fuchikami, T Niki, ...
British journal of pharmacology 145 (2), 178, 2005
1992005
Galectin-9 inhibits CD44–hyaluronan interaction and suppresses a murine model of allergic asthma
S Katoh, N Ishii, A Nobumoto, K Takeshita, SY Dai, R Shinonaga, T Niki, ...
American journal of respiratory and critical care medicine 176 (1), 27-35, 2007
1822007
Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation
T Niki, S Tsutsui, S Hirose, S Aradono, Y Sugimoto, K Takeshita, N Nishi, ...
Journal of biological chemistry 284 (47), 32344-32352, 2009
1752009
Galectin-9 suppresses tumor metastasis by blocking adhesion to endothelium and extracellular matrices
A Nobumoto, K Nagahara, S Oomizu, S Katoh, N Nishi, K Takeshita, ...
Glycobiology 18 (9), 735-744, 2008
1612008
Galectin-9 controls the therapeutic activity of 4-1BB–targeting antibodies
S Madireddi, SY Eun, SW Lee, I Nemčovičová, AK Mehta, DM Zajonc, ...
Journal of Experimental Medicine 211 (7), 1433-1448, 2014
1442014
Galectin-9 binding to Tim-3 renders activated human CD4+ T cells less susceptible to HIV-1 infection
S Elahi, T Niki, M Hirashima, H Horton
Blood, The Journal of the American Society of Hematology 119 (18), 4192-4204, 2012
1382012
Galectin-9 trafficking regulates apical-basal polarity in Madin–Darby canine kidney epithelial cells
R Mishra, M Grzybek, T Niki, M Hirashima, K Simons
Proceedings of the National Academy of Sciences 107 (41), 17633-17638, 2010
1342010
Galectin-9 functionally impairs natural killer cells in humans and mice
L Golden-Mason, RH McMahan, M Strong, R Reisdorph, S Mahaffey, ...
Journal of virology 87 (9), 4835-4845, 2013
1292013
Cell surface galectin-9 expressing Th cells regulate Th17 and Foxp3+ Treg development by galectin-9 secretion
S Oomizu, T Arikawa, T Niki, T Kadowaki, M Ueno, N Nishi, A Yamauchi, ...
PloS one 7 (11), e48574, 2012
1272012
Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner
S Oomizu, T Arikawa, T Niki, T Kadowaki, M Ueno, N Nishi, A Yamauchi, ...
Clinical immunology 143 (1), 51-58, 2012
1232012
Beneficial effect of galectin 9 on rheumatoid arthritis by induction of apoptosis of synovial fibroblasts
M Seki, KM Sakata, S Oomizu, T Arikawa, A Sakata, M Ueno, A Nobumoto, ...
Arthritis & Rheumatism: Official Journal of the American College of …, 2007
1222007
Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: a potent therapeutic tool for Th1-and/or Th17-mediated skin inflammation
H Niwa, T Satoh, Y Matsushima, K Hosoya, K Saeki, T Niki, M Hirashima, ...
Clinical immunology 132 (2), 184-194, 2009
992009
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