Luis Concha, PhD.
Luis Concha, PhD.
Amprion Inc
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Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using α-synuclein seed amplification: a cross-sectional study
A Siderowf, L Concha-Marambio, DE Lafontant, CM Farris, Y Ma, ...
The Lancet Neurology 22 (5), 407-417, 2023
Prions in the urine of patients with variant Creutzfeldt–Jakob disease
F Moda, P Gambetti, S Notari, L Concha-Marambio, M Catania, KW Park, ...
New England Journal of Medicine 371 (6), 530-539, 2014
Detection of prions in blood from patients with variant Creutzfeldt-Jakob disease
L Concha-Marambio, S Pritzkow, F Moda, F Tagliavini, JW Ironside, ...
Science Translational Medicine 8 (370), 370ra183, 2016
High diagnostic performance of independent alpha-synuclein seed amplification assays for detection of early Parkinson’s disease
MJ Russo, CD Orru, L Concha-Marambio, S Giaisi, BR Groveman, ...
Acta neuropathologica communications 9, 1-13, 2021
The Endoplasmic Reticulum Chaperone GRP78/BiP Modulates Prion Propagation in vitro and in vivo
KW Park, G Eun Kim, R Morales, F Moda, I Moreno-Gonzalez, ...
Scientific reports 7 (1), 44723, 2017
A biological definition of neuronal α-synuclein disease: towards an integrated staging system for research
T Simuni, LM Chahine, K Poston, M Brumm, T Buracchio, M Campbell, ...
The Lancet Neurology 23 (2), 178-190, 2024
Efficient prion disease transmission through common environmental materials
S Pritzkow, R Morales, A Lyon, L Concha-Marambio, A Urayama, C Soto
Journal of biological chemistry 293 (9), 3363-3373, 2018
Recent US case of variant Creutzfeldt-Jakob disease—global implications
A Maheshwari, M Fischer, P Gambetti, A Parker, A Ram, C Soto, ...
Emerging infectious diseases 21 (5), 750, 2015
Seed amplification assay for the detection of pathologic alpha-synuclein aggregates in cerebrospinal fluid
L Concha-Marambio, S Pritzkow, M Shahnawaz, CM Farris, C Soto
Nature protocols 18 (4), 1179-1196, 2023
Seed amplification assay to diagnose early Parkinson's and predict dopaminergic deficit progression
L Concha‐Marambio, CM Farris, B Holguin, Y Ma, J Seibyl, MJ Russo, ...
Movement Disorders 36 (10), 2444-2446, 2021
Accurate detection of α‐synuclein seeds in cerebrospinal fluid from isolated rapid eye movement sleep behavior disorder and patients with Parkinson's disease in the DeNovo …
L Concha‐Marambio, S Weber, CM Farris, M Dakna, E Lang, T Wicke, ...
movement disorders 38 (4), 567-578, 2023
α‐synuclein seed amplification in CSF and brain from patients with different brain distributions of pathological α‐synuclein in the context of co‐pathology and non‐LBD diagnoses
MR Arnold, DG Coughlin, BH Brumbach, DS Smirnov, ...
Annals of neurology 92 (4), 650-662, 2022
Parkinson’s Progression Markers Initiative (2023) Assessment of heterogeneity among participants in the Parkinson’s Progression Markers Initiative cohort using α-synuclein seed …
A Siderowf, L Concha-Marambio, DE Lafontant, CM Farris, Y Ma, ...
Lancet Neurol 22 (5), 407-417, 0
Treatment with a non-toxic, self-replicating anti-prion delays or prevents prion disease in vivo
R Diaz-Espinoza, R Morales, L Concha-Marambio, I Moreno-Gonzalez, ...
Molecular psychiatry 23 (3), 777-788, 2018
Preclinical detection of prions in blood of nonhuman primates infected with variant Creutzfeldt-Jakob disease
L Concha-Marambio, MA Chacon, C Soto
Emerging infectious diseases 26 (1), 34, 2020
Prions efficiently cross the intestinal barrier after oral administration: Study of the bioavailability, and cellular and tissue distribution in vivo
A Urayama, L Concha-Marambio, U Khan, J Bravo-Alegria, V Kharat, ...
Scientific Reports 6 (1), 32338, 2016
Detection of misfolded α-synuclein aggregates in cerebrospinal fluid by the protein misfolding cyclic amplification platform
L Concha-Marambio, M Shahnawaz, C Soto
Alpha-Synuclein: Methods and Protocols, 35-44, 2019
Single tryptophan mutants of FtsZ: Nucleotide binding/exchange and conformational transitions
F Montecinos-Franjola, NG James, L Concha-Marambio, JE Brunet, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844 (7), 1193-1200, 2014
α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian disorders
BF Gomes, CM Farris, Y Ma, L Concha-Marambio, R Lebovitz, B Nellgård, ...
Parkinsonism & Related Disorders 117, 105807, 2023
Cerebrospinal fluid lipoproteins inhibit α-synuclein aggregation by interacting with oligomeric species in seed amplification assays
G Bellomo, S Paciotti, L Concha-Marambio, D Rizzo, AL Wojdaƚa, ...
Molecular neurodegeneration 18 (1), 20, 2023
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