Sodium nitrite downregulates vascular NADPH oxidase and exerts antihypertensive effects in hypertension MF Montenegro, JH Amaral, LC Pinheiro, EK Sakamoto, GC Ferreira, ... Free Radical Biology and Medicine 51 (1), 144-152, 2011 | 151 | 2011 |
Gastric S-nitrosothiol formation drives the antihypertensive effects of oral sodium nitrite and nitrate in a rat model of renovascular hypertension LC Pinheiro, JH Amaral, GC Ferreira, RL Portella, CS Ceron, ... Free Radical Biology and Medicine 87, 252-262, 2015 | 99 | 2015 |
Increase in gastric pH reduces hypotensive effect of oral sodium nitrite in rats LC Pinheiro, MF Montenegro, JH Amaral, GC Ferreira, AM Oliveira, ... Free Radical Biology and Medicine 53 (4), 701-709, 2012 | 92 | 2012 |
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1 DN Meijles, S Sahoo, I Al Ghouleh, JH Amaral, R Bienes-Martinez, ... Science signaling 10 (501), eaaj1784, 2017 | 79 | 2017 |
Consistent antioxidant and antihypertensive effects of oral sodium nitrite in DOCA-salt hypertension JH Amaral, GC Ferreira, LC Pinheiro, MF Montenegro, JE Tanus-Santos Redox biology 5, 340-346, 2015 | 68 | 2015 |
Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation IA Ghouleh, S Sahoo, DN Meijles, JH Amaral, DS de Jesus, J Sembrat, ... Clinical Science 131 (15), 2019-2035, 2017 | 55 | 2017 |
Antihypertensive and antioxidant effects of a single daily dose of sodium nitrite in a model of renovascular hypertension MF Montenegro, LC Pinheiro, JH Amaral, DMO Marçal, ACT Palei, ... Naunyn-Schmiedeberg's archives of pharmacology 385, 509-517, 2012 | 53 | 2012 |
TEMPOL enhances the antihypertensive effects of sodium nitrite by mechanisms facilitating nitrite-derived gastric nitric oxide formation JH Amaral, MF Montenegro, LC Pinheiro, GC Ferreira, RP Barroso, ... Free Radical Biology and Medicine 65, 446-455, 2013 | 52 | 2013 |
Vascular xanthine oxidoreductase contributes to the antihypertensive effects of sodium nitrite in l-NAME hypertension MF Montenegro, LC Pinheiro, JH Amaral, GC Ferreira, RL Portella, ... Naunyn-Schmiedeberg's archives of pharmacology 387, 591-598, 2014 | 48 | 2014 |
The relationship between blood and serum lead levels in peripartum women and their respective umbilical cords JH Amaral, VB Rezende, SM Quintana, RF Gerlach, F Barbosa Jr, ... Basic & clinical pharmacology & toxicology 107 (6), 971-975, 2010 | 47 | 2010 |
Antioxidant and antihypertensive responses to oral nitrite involves activation of the Nrf2 pathway JH Amaral, ES Rizzi, R Alves-Lopes, LC Pinheiro, RC Tostes, ... Free Radical Biology and Medicine 141, 261-268, 2019 | 44 | 2019 |
Oral nitrite circumvents antiseptic mouthwash-induced disruption of enterosalivary circuit of nitrate and promotes nitrosation and blood pressure lowering effect LC Pinheiro, GC Ferreira, JH Amaral, RL Portella, S de OC Tella, ... Free Radical Biology and Medicine 101, 226-235, 2016 | 39 | 2016 |
Nitrite exerts antioxidant effects, inhibits the mTOR pathway and reverses hypertension-induced cardiac hypertrophy DA Guimaraes, MA Dos Passos, E Rizzi, LC Pinheiro, JH Amaral, ... Free Radical Biology and Medicine 120, 25-32, 2018 | 38 | 2018 |
Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype I Al Ghouleh, DN Meijles, S Mutchler, Q Zhang, S Sahoo, A Gorelova, ... Proceedings of the National Academy of Sciences 113 (36), E5308-E5317, 2016 | 36 | 2016 |
Nitrite treatment downregulates vascular MMP-2 activity and inhibits vascular remodeling in hypertension independently of its antihypertensive effects E Rizzi, JH Amaral, DA Guimaraes, SO Conde-Tella, LC Pinheiro, ... Free Radical Biology and Medicine 130, 234-243, 2019 | 33 | 2019 |
Hydrogen peroxide modulates phenylephrine-induced contractile response in renal hypertensive rat aorta BR Silva, L Pernomian, MD Grando, JH Amaral, JE Tanus-Santos, ... European journal of pharmacology 721 (1-3), 193-200, 2013 | 33 | 2013 |
Analytical method for determination of nitric oxide in zebrafish larvae: toxicological and pharmacological applications CE Leite, A da Cruz Teixeira, FF Cruz, SC Concatto, JH Amaral, ... Analytical biochemistry 421 (2), 534-540, 2012 | 28 | 2012 |
Should we measure serum or plasma lead concentrations? VB Rezende, JH Amaral, RF Gerlach, F Barbosa Jr, JE Tanus-Santos Journal of Trace Elements in Medicine and Biology 24 (3), 147-151, 2010 | 26 | 2010 |
The antihypertensive effects of sodium nitrite are not associated with circulating angiotensin converting enzyme inhibition LC Pinheiro, JH Amaral, GC Ferreira, MF Montenegro, GH Oliveira-Paula, ... Nitric Oxide 40, 52-59, 2014 | 24 | 2014 |
TNF-α inhibition decreases MMP-2 activity, reactive oxygen species formation and improves hypertensive vascular hypertrophy independent of its effects on blood pressure BR Mattos, GF Bonacio, TR Vitorino, VT Garcia, JH Amaral, ... Biochemical Pharmacology 180, 114121, 2020 | 23 | 2020 |