| Bacterial killing by complement requires membrane attack complex formation via surface‐bound C5 convertases DAC Heesterbeek, BW Bardoel, ES Parsons, I Bennett, M Ruyken, ... The EMBO journal 38 (4), e99852, 2019 | 92 | 2019 |
| Electrostatic clustering and free energy calculations provide a foundation for protein design and optimization RD Gorham, CA Kieslich, D Morikis Annals of biomedical engineering 39, 1252-1263, 2011 | 72 | 2011 |
| Molecular insights into the surface-specific arrangement of complement C5 convertase enzymes ETM Berends, RD Gorham, M Ruyken, JA Soppe, H Orhan, PC Aerts, ... BMC biology 13, 1-13, 2015 | 70 | 2015 |
| Staphylococcal immune evasion proteins: structure, function, and host adaptation KJ Koymans, M Vrieling, RD Gorham, JAG van Strijp Staphylococcus aureus: microbiology, pathology, immunology, therapy and …, 2017 | 67 | 2017 |
| Functional characterization of alternative and classical pathway C3/C5 convertase activity and inhibition using purified models SA Zwarthoff, ETM Berends, S Mol, M Ruyken, PC Aerts, M Józsi, ... Frontiers in immunology 9, 1691, 2018 | 58 | 2018 |
| Molecular dynamics in drug design: new generations of compstatin analogs P Tamamis, A Lopez de Victoria, RD Gorham Jr, ML Bellows‐Peterson, ... Chemical biology & drug design 79 (5), 703-718, 2012 | 50 | 2012 |
| Quantitative modeling of the alternative pathway of the complement system N Zewde, RD Gorham Jr, A Dorado, D Morikis PloS one 11 (3), e0152337, 2016 | 49 | 2016 |
| The influence of TAP1 and TAP2 gene polymorphisms on TAP function and its inhibition by viral immune evasion proteins P Praest, RD Luteijn, IGJ Brak-Boer, J Lanfermeijer, H Hoelen, L Ijgosse, ... Molecular immunology 101, 55-64, 2018 | 40 | 2018 |
| Let’s tie the knot: marriage of complement and adaptive immunity in pathogen evasion, for better or worse KM Bennett, SHM Rooijakkers, RD Gorham Jr Frontiers in Microbiology 8, 89, 2017 | 40 | 2017 |
| An evaluation of Poisson–Boltzmann electrostatic free energy calculations through comparison with experimental mutagenesis data RD Gorham Jr, CA Kieslich, A Nichols, NU Sausman, M Foronda, ... Biopolymers 95 (11), 746-754, 2011 | 38 | 2011 |
| Is the rigid-body assumption reasonable?: Insights into the effects of dynamics on the electrostatic analysis of barnase–barstar CA Kieslich, RD Gorham Jr, D Morikis Journal of Non-Crystalline Solids 357 (2), 707-716, 2011 | 36 | 2011 |
| A new generation of potent complement inhibitors of the compstatin family A López de Victoria, RD Gorham Jr, ML Bellows‐Peterson, J Ling, DD Lo, ... Chemical biology & drug design 77 (6), 431-440, 2011 | 31 | 2011 |
| Hybrid flagellin as a T cell independent vaccine scaffold KM Bennett, RD Gorham, V Gusti, L Trinh, D Morikis, DD Lo BMC biotechnology 15, 1-12, 2015 | 29 | 2015 |
| Novel compstatin family peptides inhibit complement activation by drusen-like deposits in human retinal pigmented epithelial cell cultures RD Gorham Jr, DL Forest, P Tamamis, AL de Victoria, M Kraszni, ... Experimental Eye Research 116, 96-108, 2013 | 28 | 2013 |
| Molecular analysis of the interaction between staphylococcal virulence factor Sbi-IV and complement C3d RD Gorham, W Rodriguez, D Morikis Biophysical journal 106 (5), 1164-1173, 2014 | 26 | 2014 |
| Viral regulators of complement activation: structure, function and evolution H Ojha, HS Panwar, RD Gorham Jr, D Morikis, A Sahu Molecular Immunology 61 (2), 89-99, 2014 | 25 | 2014 |
| New compstatin peptides containing N-terminal extensions and non-natural amino acids exhibit potent complement inhibition and improved solubility characteristics RD Gorham Jr, DL Forest, GA Khoury, J Smadbeck, CN Beecher, ... Journal of medicinal chemistry 58 (2), 814-826, 2015 | 20 | 2015 |
| Complement Inhibition by Staphylococcus aureus: Electrostatics of C3d–EfbC and C3d–Ehp Association RD Gorham, CA Kieslich, D Morikis Cellular and Molecular Bioengineering 5, 32-43, 2012 | 18 | 2012 |
| A theoretical view of the C3d: CR2 binding controversy RR Mohan, RD Gorham Jr, D Morikis Molecular Immunology 64 (1), 112-122, 2015 | 17 | 2015 |
| Virtual screening of chemical compounds for discovery of complement C3 ligands RR Mohan, M Wilson, RD Gorham Jr, RES Harrison, VA Morikis, ... ACS omega 3 (6), 6427-6438, 2018 | 16 | 2018 |
