M2-like macrophages are responsible for collagen degradation through a mannose receptor–mediated pathway DH Madsen, D Leonard, A Masedunskas, A Moyer, HJ Jürgensen, ... Journal of Cell Biology 202 (6), 951-966, 2013 | 335 | 2013 |
Collagen density regulates the activity of tumor-infiltrating T cells DE Kuczek, AMH Larsen, ML Thorseth, M Carretta, A Kalvisa, ... Journal for immunotherapy of cancer 7, 1-15, 2019 | 286 | 2019 |
Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation DH Madsen, LH Engelholm, S Ingvarsen, T Hillig, RA Wagenaar-Miller, ... Journal of Biological Chemistry 282 (37), 27037-27045, 2007 | 131 | 2007 |
The non-phagocytic route of collagen uptake: a distinct degradation pathway DH Madsen, S Ingvarsen, HJ Jürgensen, MC Melander, L Kjøller, A Moyer, ... Journal of Biological Chemistry 286 (30), 26996-27010, 2011 | 123 | 2011 |
Tumor-associated macrophages derived from circulating inflammatory monocytes degrade collagen through cellular uptake DH Madsen, HJ Jürgensen, MS Siersbæk, DE Kuczek, LG Cloud, S Liu, ... Cell reports 21 (13), 3662-3671, 2017 | 114 | 2017 |
A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180 HJ Jürgensen, DH Madsen, S Ingvarsen, MC Melander, H Gårdsvoll, ... Journal of Biological Chemistry 286 (37), 32736-32748, 2011 | 112 | 2011 |
Fibroblast activation protein (FAP) accelerates collagen degradation and clearance from lungs in mice MH Fan, Q Zhu, HH Li, HJ Ra, S Majumdar, DL Gulick, JA Jerome, ... Journal of Biological Chemistry 291 (15), 8070-8089, 2016 | 93 | 2016 |
Immune modulatory properties of collagen in cancer AMA Rømer, ML Thorseth, DH Madsen Frontiers in immunology 12, 791453, 2021 | 88 | 2021 |
Collagen density modulates the immunosuppressive functions of macrophages AMH Larsen, DE Kuczek, A Kalvisa, MS Siersbæk, ML Thorseth, ... The Journal of Immunology 205 (5), 1461-1472, 2020 | 75 | 2020 |
The collagen receptor uPARAP/Endo180 in tissue degradation and cancer MC Melander, HJ Jürgensen, DH Madsen, LH Engelholm, N Behrendt International journal of oncology 47 (4), 1177-1188, 2015 | 75 | 2015 |
The collagen receptor uPARAP/Endo180 LH Engelholm, S Ingvarsen, HJ Jurgensen, T Hillig, DH Madsen, ... Front Biosci 14 (6), 2103-2114, 2009 | 73 | 2009 |
Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients C Jensen, DH Madsen, M Hansen, H Schmidt, IM Svane, MA Karsdal, ... Journal for Immunotherapy of Cancer 6, 1-10, 2018 | 65 | 2018 |
Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis S Ingvarsen, A Porse, C Erpicum, L Maertens, HJ Jürgensen, DH Madsen, ... Journal of Biological Chemistry 288 (15), 10195-10204, 2013 | 62 | 2013 |
Increased expression of the collagen internalization receptor uPARAP/Endo180 in the stroma of head and neck cancer J Sulek, RA Wagenaar-Miller, J Shireman, A Molinolo, DH Madsen, ... Journal of Histochemistry & Cytochemistry 55 (4), 347-353, 2007 | 59 | 2007 |
Complex determinants in specific members of the mannose receptor family govern collagen endocytosis HJ Jürgensen, K Johansson, DH Madsen, A Porse, MC Melander, ... Journal of Biological Chemistry 289 (11), 7935-7947, 2014 | 57 | 2014 |
Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis DH Madsen, HJ Jürgensen, S Ingvarsen, MC Melander, B Vainer, ... The Journal of pathology 227 (1), 94-105, 2012 | 56 | 2012 |
Blockade of beta-adrenergic receptors reduces cancer growth and enhances the response to anti-CTLA4 therapy by modulating the tumor microenvironment KY Fjæstad, AMA Rømer, V Goitea, AZ Johansen, ML Thorseth, ... Oncogene 41 (9), 1364-1375, 2022 | 51 | 2022 |
A CCR2 macrophage endocytic pathway mediates extravascular fibrin clearance in vivo MP Motley, DH Madsen, HJ Jürgensen, DE Spencer, R Szabo, ... Blood, The Journal of the American Society of Hematology 127 (9), 1085-1096, 2016 | 43 | 2016 |
Dimerization of endogenous MT1-MMP is a regulatory step in the activation of the 72-kDa gelatinase MMP-2 on fibroblasts and fibrosarcoma cells S Ingvarsen, DH Madsen, T Hillig, LR Lund, K Holmbeck, N Behrendt, ... Walter de Gruyter 389 (7), 943-953, 2008 | 43 | 2008 |
A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor T Hillig, LH Engelholm, S Ingvarsen, DH Madsen, H Gardsvoll, JK Larsen, ... Journal of biological chemistry 283 (22), 15217-15223, 2008 | 40 | 2008 |