Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress R Ghosh, L Wang, ES Wang, BGK Perera, A Igbaria, S Morita, K Prado, ... Cell 158 (3), 534-548, 2014 | 490 | 2014 |
A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy MV Alavi, S Bette, S Schimpf, F Schuettauf, U Schraermeyer, HF Wehrl, ... Brain 130 (4), 1029-1042, 2007 | 307 | 2007 |
A new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics D Nguyen, MV Alavi, KY Kim, T Kang, RT Scott, YH Noh, JD Lindsey, ... Cell death & disease 2 (12), e240-e240, 2011 | 245 | 2011 |
Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload J Piquereau, F Caffin, M Novotova, A Prola, A Garnier, P Mateo, D Fortin, ... Cardiovascular research 94 (3), 408-417, 2012 | 209 | 2012 |
Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis ME Ward, R Chen, HY Huang, C Ludwig, M Telpoukhovskaia, A Taubes, ... Science translational medicine 9 (385), eaah5642, 2017 | 186 | 2017 |
Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics MV Alavi, N Fuhrmann Molecular neurodegeneration 8 (1), 1-12, 2013 | 150 | 2013 |
Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse J Sancho-Pelluz, MV Alavi, A Sahaboglu, S Kustermann, P Farinelli, ... Cell death & disease 1 (2), e24-e24, 2010 | 134 | 2010 |
Type IV collagens and basement membrane diseases: cell biology and pathogenic mechanisms M Mao, MV Alavi, C Labelle-Dumais, DB Gould Current topics in membranes 76, 61-116, 2015 | 97 | 2015 |
Electrophysiological and histologic assessment of retinal ganglion cell fate in a mouse model for OPA1-associated autosomal dominant optic atrophy P Heiduschka, S Schnichels, N Fuhrmann, S Hofmeister, U Schraermeyer, ... Investigative ophthalmology & visual science 51 (3), 1424-1431, 2010 | 83 | 2010 |
The protein translocon of the plastid envelopes A Vojta, MV Alavi, T Becker, F Hörmann, M Küchler, J Soll, R Thomson, ... Journal of Biological Chemistry 279 (20), 21401-21405, 2004 | 70 | 2004 |
Genomic rearrangements in OPA1 are frequent in patients with autosomal dominant optic atrophy N Fuhrmann, MV Alavi, P Bitoun, S Woernle, G Auburger, B Leo-Kottler, ... Journal of medical genetics 46 (2), 136-144, 2009 | 60 | 2009 |
Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy MV Alavi, N Fuhrmann, HP Nguyen, P Yu-Wai-Man, P Heiduschka, ... Experimental neurology 220 (2), 404-409, 2009 | 53 | 2009 |
Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1‐deficient mice F Caffin, A Prola, J Piquereau, M Novotova, DJ David, A Garnier, D Fortin, ... The Journal of physiology 591 (23), 6017-6037, 2013 | 50 | 2013 |
Col4a1 mutations cause progressive retinal neovascular defects and retinopathy MV Alavi, M Mao, BT Pawlikowski, M Kvezereli, JL Duncan, RT Libby, ... Scientific reports 6 (1), 1-12, 2016 | 47 | 2016 |
A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16 V Carelli, S Schimpf, N Fuhrmann, ML Valentino, C Zanna, L Iommarini, ... Human molecular genetics 20 (10), 1893-1905, 2011 | 39 | 2011 |
Targeted OMA1 therapies for cancer MV Alavi International journal of cancer 145 (9), 2330-2341, 2019 | 38 | 2019 |
Aging and vision MV Alavi Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 393-399, 2016 | 25 | 2016 |
Strain-dependent anterior segment dysgenesis and progression to glaucoma in Col4a1 mutant mice M Mao, RS Smith, MV Alavi, JK Marchant, M Cosma, RT Libby, SWM John, ... Investigative ophthalmology & visual science 56 (11), 6823-6831, 2015 | 23 | 2015 |
In vivo visualization of endoplasmic reticulum stress in the retina using the ERAI reporter mouse MV Alavi, WC Chiang, H Kroeger, D Yasumura, MT Matthes, T Iwawaki, ... Investigative ophthalmology & visual science 56 (11), 6961-6970, 2015 | 21 | 2015 |
Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy N Fuhrmann, S Schimpf, Y Kamenisch, B Leo-Kottler, C Alexander, ... Molecular neurodegeneration 5 (1), 25, 2010 | 19 | 2010 |