Nadine Darwiche
Nadine Darwiche
Professor of Biochemistry and Molecular Genetics, American University of Beirut
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What made sesquiterpene lactones reach cancer clinical trials?
A Ghantous, H Gali-Muhtasib, H Vuorela, NA Saliba, N Darwiche
Drug discovery today 15 (15-16), 668-678, 2010
Parthenolide: from plant shoots to cancer roots
A Ghantous, A Sinjab, Z Herceg, N Darwiche
Drug discovery today 18 (17-18), 894-905, 2013
Molecular pathway for thymoquinone-induced cell-cycle arrest and apoptosis in neoplastic keratinocytes
HU Gali-Muhtasib, WG Abou Kheir, LA Kheir, N Darwiche, PA Crooks
Anti-cancer drugs 15 (4), 389-399, 2004
Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis
H Gali-Muhtasib, R Hmadi, M Kareh, R Tohme, N Darwiche
Apoptosis 20 (12), 1531-1562, 2015
Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma.
AB Glick, MM Lee, N Darwiche, AB Kulkarni, S Karlsson, SH Yuspa
Genes & development 8 (20), 2429-2440, 1994
Retinoids: a journey from the molecular structures and mechanisms of action to clinical uses in dermatology and adverse effects
S Khalil, T Bardawil, C Stephan, N Darwiche, O Abbas, AG Kibbi, ...
Journal of Dermatological Treatment 28 (8), 684-696, 2017
Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells
H El Hajj, Z Dassouki, C Berthier, E Raffoux, L Ades, O Legrand, R Hleihel, ...
Blood, The Journal of the American Society of Hematology 125 (22), 3447-3454, 2015
Protective effect of vitamin E on ultraviolet B light–induced damage in keratinocytes
S Maalouf, M El‐Sabban, N Darwiche, H Gali‐Muhtasib
Molecular Carcinogenesis: Published in cooperation with the University of …, 2002
Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis
A Kurtz, HL Wang, N Darwiche, V Harris, A Wellstein
Oncogene 14 (22), 2671-2681, 1997
A journey under the sea: the quest for marine anti-cancer alkaloids
R Tohme, N Darwiche, H Gali-Muhtasib
Molecules 16 (11), 9665-9696, 2011
MouseSprr2Genes: A Clustered Family of Genes Showing Differential Expression in Epithelial Tissues
HJ Song, G Poy, N Darwiche, U Lichti, T Kuroki, PM Steinert, T Kartasova
Genomics 55 (1), 28-42, 1999
Sequence and expression patterns of mouse SPR1: correlation of expression with epithelial function
T Kartasova, N Darwiche, Y Kohno, H Koizumi, S Osada, N Huh, U Lichti, ...
Journal of Investigative Dermatology 106 (2), 294-304, 1996
Autocrine transforming growth factor α is dispensible for v-rasHa-induced epidermal neoplasia: potential involvement of alternate epidermal growth factor receptor ligands
AA Dlugosz, C Cheng, EK Williams, N Darwiche, PJ Dempsey, B Mann, ...
Cancer research 55 (9), 1883-1893, 1995
Retinoid status controls the appearance of reserve cells and keratin expression in mouse cervical epithelium
N Darwiche, G Celli, L Sly, F Lancillotti, LM De Luca
Cancer research 53 (10), 2287-2299, 1993
Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors
N Darwiche, G Celli, T Tennenbaum, AB Glick, SH Yuspa, LM De Luca
Cancer research 55 (13), 2774-2782, 1995
Expression of cornifin in squamous differentiating epithelial tissues, including psoriatic and retinoic acid-treated skin
W Fujimoto, KW Marvin, MD George, G Celli, N Darwiche, LM De Luca, ...
Journal of investigative dermatology 101 (3), 268-274, 1993
Evidence against a direct cytotoxic effect of alpha interferon and zidovudine in HTLV-I associated adult T cell leukemia/lymphoma
A Bazarbachi, R Nasr, ME El-Sabban, A Mahe, R Mahieux, A Gessain, ...
Leukemia 14 (4), 716-721, 2000
Retinoids in differentiation and neoplasia
LM De Luca
Scientific American-Science and Medicine 2, 28-37, 1995
Loss of retinoic acid receptors in mouse skin and skin tumors is associated with activation of the rasHa oncogene and high risk for premalignant progression
N Darwiche, G Scita, C Jones, S Rutberg, E Greenwald, T Tennenbaum, ...
Cancer research 56 (21), 4942-4949, 1996
Overexpression of retinoic acid receptors alpha and gamma into neoplastic epidermal cells causes retinoic acid-induced growth arrest and apoptosis
A Hatoum, ME El-Sabban, J Khoury, SH Yuspa, N Darwiche
Carcinogenesis 22 (12), 1955-1963, 2001
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