| Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance T Downing, H Imamura, S Decuypere, TG Clark, GH Coombs, JA Cotton, ... Genome research 21 (12), 2143-2156, 2011 | 468 | 2011 |
| Leishmania infections: Molecular targets and diagnosis M Akhoundi, T Downing, J Votępka, K Kuhls, J Lukeš, A Cannet, C Ravel, ... Molecular aspects of medicine 57, 1-29, 2017 | 345 | 2017 |
| Genomic Confirmation of Hybridisation and Recent Inbreeding in a Vector-Isolated Leishmania Population MB Rogers, T Downing, BA Smith, H Imamura, M Sanders, M Svobodova, ... PLoS genetics 10 (1), e1004092, 2014 | 159 | 2014 |
| Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent H Imamura, T Downing, F Van den Broeck, MJ Sanders, S Rijal, S Sundar, ... Elife 5, e12613, 2016 | 154 | 2016 |
| Adaptive mechanisms in pathogens: universal aneuploidy in Leishmania A Mannaert, T Downing, H Imamura, JC Dujardin Trends in Parasitology, 2012 | 145 | 2012 |
| The avian Toll-Like receptor pathway—Subtle differences amidst general conformity P Cormican, AT Lloyd, T Downing, SJ Connell, D Bradley, C O’Farrelly Developmental & Comparative Immunology 33 (9), 967-973, 2009 | 136 | 2009 |
| Global genome diversity of the Leishmania donovani complex SU Franssen, C Durrant, O Stark, B Moser, T Downing, H Imamura, ... Elife 9, e51243, 2020 | 92 | 2020 |
| Development and evaluation of a novel loop-mediated isothermal amplification assay for diagnosis of cutaneous and visceral leishmaniasis ER Adams, G Schoone, I Versteeg, MA Gomez, E Diro, Y Mori, D Perlee, ... Journal of Clinical Microbiology 56 (7), 10.1128/jcm. 00386-18, 2018 | 88 | 2018 |
| The differential evolutionary dynamics of avian cytokine and TLR gene classes T Downing, AT Lloyd, C O’Farrelly, DG Bradley The Journal of Immunology 184 (12), 6993-7000, 2010 | 76 | 2010 |
| In vitro selection of miltefosine resistance in promastigotes of Leishmania donovani from Nepal: genomic and metabolomic characterization CD Shaw, J Lonchamp, T Downing, H Imamura, TM Freeman, JA Cotton, ... Molecular Microbiology 99 (6), 1134-1148, 2016 | 73 | 2016 |
| An Escherichia coli ST131 pangenome atlas reveals population structure and evolution across 4,071 isolates AG Decano, T Downing Scientific reports 9 (1), 17394, 2019 | 68 | 2019 |
| Genome-wide SNP and microsatellite variation illuminate population-level epidemiology in the Leishmania donovani species complex T Downing, O Stark, M Vanaerschot, H Imamura, M Sanders, ... Infection, Genetics and Evolution, 2011 | 62 | 2011 |
| The triploid East African Highland Banana (EAHB) genepool is genetically uniform arising from a single ancestral clone that underwent population expansion by vegetative propagation M Kitavi, T Downing, J Lorenzen, D Karamura, M Onyango, M Nyine, ... Theoretical and Applied Genetics 129, 547-561, 2016 | 50 | 2016 |
| Genomic surveillance of Escherichia coli ST131 identifies local expansion and serial replacement of subclones C Ludden, AG Decano, D Jamrozy, D Pickard, D Morris, J Parkhill, ... Microbial Genomics 6 (4), 2020 | 47 | 2020 |
| The genome of Leishmania adleri from a mammalian host highlights chromosome fission in Sauroleishmania S Coughlan, P Mulhair, M Sanders, G Schonian, JA Cotton, T Downing Scientific reports 7 (1), 43747, 2017 | 35 | 2017 |
| Leishmania naiffi and Leishmania guyanensis reference genomes highlight genome structure and gene evolution in the Viannia subgenus S Coughlan, AS Taylor, E Feane, M Sanders, G Schonian, JA Cotton, ... Royal Society open science 5 (4), 172212, 2018 | 34 | 2018 |
| Redeploying β-lactam antibiotics as a novel antivirulence strategy for the treatment of methicillin-resistant Staphylococcus aureus infections EM Waters, JK Rudkin, S Coughlan, GC Clair, JN Adkins, S Gore, G Xia, ... The Journal of infectious diseases 215 (1), 80-87, 2017 | 31 | 2017 |
| Tackling Drug Resistant Infection Outbreaks of Global Pandemic Escherichia coli ST131 Using Evolutionary and Epidemiological Genomics T Downing Microorganisms 3 (2), 236-267, 2015 | 27 | 2015 |
| Genetic Markers for SSG Resistance in Leishmania donovani and SSG Treatment Failure in Visceral Leishmaniasis Patients of the Indian Subcontinent M Vanaerschot, S Decuypere, T Downing, H Imamura, O Stark, ... The Journal of infectious diseases 206 (5), 752-755, 2012 | 26 | 2012 |
| Complete assembly of Escherichia coli sequence type 131 genomes using long reads demonstrates antibiotic resistance gene variation within diverse plasmid and chromosomal contexts AG Decano, C Ludden, T Feltwell, K Judge, J Parkhill, T Downing Msphere 4 (3), 10.1128/msphere. 00130-19, 2019 | 25 | 2019 |
Jean-Claude DujardinInstitute of Tropical MedicineVerified email at itg.be
