The Marinopyrroles, Antibiotics of an Unprecedented Structure Class from a Marine Streptomyces sp. CC Hughes, A Prieto-Davo, PR Jensen, W Fenical Organic letters 10 (4), 629-631, 2008 | 402 | 2008 |
Inhibition of NADPH oxidase activation in endothelial cells by ortho-methoxy-substituted catechols DK Johnson, KJ Schillinger, DM Kwait, CV Hughes, EJ McNamara, ... Endothelium 9 (3), 191-203, 2002 | 231 | 2002 |
Antibacterials from the sea CC Hughes, W Fenical Chemistry–A European Journal 16 (42), 12512-12525, 2010 | 217 | 2010 |
The ammosamides: structures of cell cycle modulators from a marine-derived Streptomyces species CC Hughes, JB MacMillan, SP Gaudêncio, PR Jensen, W Fenical Angewandte Chemie (International ed. in English) 48 (4), 725, 2009 | 216 | 2009 |
Concise total synthesis of (-)-frondosin B using a novel palladium-catalyzed cyclization CC Hughes, D Trauner Angewandte Chemie-International Edition 41 (9), 1569-1572, 2002 | 200 | 2002 |
Concise synthesis of (±)-rhazinilam through direct coupling AL Bowie, CC Hughes, D Trauner Organic Letters 7 (23), 5207-5209, 2005 | 167 | 2005 |
Total synthesis of (−)-heptemerone B and (−)-guanacastepene E AK Miller, CC Hughes, JJ Kennedy-Smith, SN Gradl, D Trauner Journal of the American Chemical Society 128 (51), 17057-17062, 2006 | 157 | 2006 |
Bile salt–induced intermolecular disulfide bond formation activates Vibrio cholerae virulence M Yang, Z Liu, C Hughes, AM Stern, H Wang, Z Zhong, B Kan, W Fenical, ... Proceedings of the National Academy of Sciences 110 (6), 2348-2353, 2013 | 150 | 2013 |
Structures, reactivities, and antibiotic properties of the marinopyrroles A− F CC Hughes, CA Kauffman, PR Jensen, W Fenical The Journal of organic chemistry 75 (10), 3240-3250, 2010 | 143 | 2010 |
Marinopyrrole A target elucidation by acyl dye transfer CC Hughes, YL Yang, WT Liu, PC Dorrestein, JJL Clair, W Fenical Journal of the American Chemical Society 131 (34), 12094-12096, 2009 | 139 | 2009 |
Ammosamides A and B target myosin CC Hughes, JB MacMillan, SP Gaudêncio, W Fenical, JJ La Clair Angewandte Chemie 121 (4), 742-746, 2009 | 131 | 2009 |
Discovery, biosynthesis and stress-related accumulation of dolabradiene-derived defenses in maize S Mafu, Y Ding, KM Murphy, O Yaacoobi, JB Addison, Q Wang, Z Shen, ... Plant physiology 176 (4), 2677-2690, 2018 | 114 | 2018 |
Flavoenzyme-Catalyzed Atropo-Selective N,C-Bipyrrole Homocoupling in Marinopyrrole Biosynthesis K Yamanaka, KS Ryan, TAM Gulder, CC Hughes, BS Moore Journal of the American Chemical Society 134 (30), 12434-12437, 2012 | 102 | 2012 |
Function-Oriented Biosynthesis of β-Lactone Proteasome Inhibitors in Salinispora tropica M Nett, TAM Gulder, AJ Kale, CC Hughes, BS Moore Journal of medicinal chemistry 52 (19), 6163-6167, 2009 | 89 | 2009 |
Chlorizidine, a Cytotoxic 5H-Pyrrolo[2,1-a]isoindol-5-one-Containing Alkaloid from a Marine Streptomyces sp. X Alvarez-Mico, PR Jensen, W Fenical, CC Hughes Organic letters 15 (5), 988-991, 2013 | 83 | 2013 |
Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus NM Haste, CC Hughes, DN Tran, W Fenical, PR Jensen, V Nizet, ... Antimicrobial agents and chemotherapy 55 (7), 3305-3312, 2011 | 82 | 2011 |
An electrochemical approach to the guanacastepenes CC Hughes, AK Miller, D Trauner Organic Letters 7 (16), 3425-3428, 2005 | 82 | 2005 |
Multiple genes recruited from hormone pathways partition maize diterpenoid defences Y Ding, KM Murphy, E Poretsky, S Mafu, B Yang, SN Char, ... Nature Plants 5 (10), 1043-1056, 2019 | 79 | 2019 |
Total synthesis of the ammosamides CC Hughes, W Fenical Journal of the American Chemical Society 132 (8), 2528-2529, 2010 | 77 | 2010 |
Palladium-catalyzed couplings to nucleophilic heteroarenes: the total synthesis of (−)-frondosin B CC Hughes, D Trauner Tetrahedron 60 (43), 9675-9686, 2004 | 77 | 2004 |