Fadi Towfic
Fadi Towfic
Prometheus Biosciences
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Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma
BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, FE Davies, ...
Blood, The Journal of the American Society of Hematology 132 (6), 587-597, 2018
A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis
BA Walker, K Mavrommatis, CP Wardell, TC Ashby, M Bauer, F Davies, ...
Leukemia 33 (1), 159-170, 2019
Genetic variants synthesize to produce paneth cell phenotypes that define subtypes of Crohn's disease
KL VanDussen, TC Liu, D Li, F Towfic, N Modiano, R Winter, ...
Gastroenterology 146 (1), 200-209, 2014
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse
JA Carrero, B Calderon, F Towfic, MN Artyomov, ER Unanue
PloS one 8 (3), e59701, 2013
Genome-wide siRNA screen for mediators of NF-κB activation
BE Gewurz, F Towfic, JC Mar, NP Shinners, K Takasaki, B Zhao, ...
Proceedings of the National Academy of Sciences 109 (7), 2467-2472, 2012
Laquinimod arrests experimental autoimmune encephalomyelitis by activating the aryl hydrocarbon receptor
J Kaye, V Piryatinsky, T Birnberg, T Hingaly, E Raymond, R Kashi, ...
Proceedings of the National Academy of Sciences 113 (41), E6145-E6152, 2016
Iberdomide (CC-220) is a potent cereblon E3 ligase modulator with antitumor and immunostimulatory activities in lenalidomide-and pomalidomide-resistant multiple myeloma cells …
CC Bjorklund, J Kang, M Amatangelo, A Polonskaia, M Katz, H Chiu, ...
Leukemia 34 (4), 1197-1201, 2020
Protein-RNA interface residue prediction using machine learning: an assessment of the state of the art
RR Walia, C Caragea, BA Lewis, F Towfic, M Terribilini, Y El-Manzalawy, ...
BMC bioinformatics 13, 1-20, 2012
Pridopidine activates neuroprotective pathways impaired in Huntington Disease
M Geva, R Kusko, H Soares, KD Fowler, T Birnberg, S Barash, ...
Human molecular genetics 25 (18), 3975-3987, 2016
High subclonal fraction of 17p deletion is associated with poor prognosis in multiple myeloma
A Thakurta, M Ortiz, P Blecua, F Towfic, J Corre, NV Serbina, E Flynt, Z Yu, ...
Blood, The Journal of the American Society of Hematology 133 (11), 1217-1221, 2019
Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma
S Gooding, N Ansari-Pour, F Towfic, M Ortiz Estévez, PP Chamberlain, ...
Blood 137 (2), 232-237, 2021
Struct-NB: predicting protein-RNA binding sites using structural features
F Towfic, C Caragea, DC Gemperline, D Dobbs, V Honavar
International journal of data mining and bioinformatics 4 (1), 21-43, 2010
Comparing the biological impact of glatiramer acetate with the biological impact of a generic
F Towfic, JM Funt, KD Fowler, S Bakshi, E Blaugrund, MN Artyomov, ...
PloS one 9 (1), e83757, 2014
Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma
E Flynt, K Bisht, V Sridharan, M Ortiz, F Towfic, A Thakurta
Cells 9 (2), 287, 2020
Aligning biomolecular networks using modular graph kernels
F Towfic, MHW Greenlee, V Honavar
Algorithms in Bioinformatics: 9th International Workshop, WABI 2009 …, 2009
Detection of gene orthology from gene co-expression and protein interaction networks
F Towfic, S VanderPIas, CA OIiver, OI Couture, CK TuggIe, ...
BMC bioinformatics 11, 1-10, 2010
Multiple Myeloma DREAM Challenge reveals epigenetic regulator PHF19 as marker of aggressive disease
MJ Mason, C Schinke, CLP Eng, F Towfic, F Gruber, A Dervan, BS White, ...
Leukemia 34 (7), 1866-1874, 2020
A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis
CJ Ross, F Towfic, J Shankar, D Laifenfeld, M Thoma, M Davis, B Weiner, ...
Genome medicine 9 (1), 1-15, 2017
Functional effects of the antigen glatiramer acetate are complex and tightly associated with its composition
T Hasson, S Kolitz, F Towfic, D Laifenfeld, S Bakshi, O Beriozkin, ...
Journal of Neuroimmunology 290, 84-95, 2016
Leveraging existing data sets to generate new insights into Alzheimer’s disease biology in specific patient subsets
KD Fowler, JM Funt, MN Artyomov, B Zeskind, SE Kolitz, F Towfic
Scientific reports 5 (1), 1-14, 2015
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