Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms E Piskounova, C Polytarchou, JE Thornton, RJ LaPierre, C Pothoulakis, ... Cell 147 (5), 1066-1079, 2011 | 710 | 2011 |
An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis M Hatziapostolou, C Polytarchou, E Aggelidou, A Drakaki, GA Poultsides, ... Cell 147 (6), 1233-1247, 2011 | 555 | 2011 |
Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells D Iliopoulos, M Lindahl-Allen, C Polytarchou, HA Hirsch, PN Tsichlis, ... Molecular cell 39 (5), 761-772, 2010 | 464 | 2010 |
MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis G Koukos, C Polytarchou, JL Kaplan, A Morley–Fletcher, B Gras–Miralles, ... Gastroenterology 145 (4), 842-852. e2, 2013 | 257 | 2013 |
FGF-2 regulates cell proliferation, migration, and angiogenesis through an NDY1/KDM2B-miR-101-EZH2 pathway F Kottakis, C Polytarchou, P Foltopoulou, I Sanidas, SC Kampranis, ... Molecular cell 43 (2), 285-298, 2011 | 255 | 2011 |
MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells D Iliopoulos, C Polytarchou, M Hatziapostolou, F Kottakis, IG Maroulakou, ... Science signaling 2 (92), ra62-ra62, 2009 | 242 | 2009 |
Hydrogen peroxide stimulates proliferation and migration of human prostate cancer cells through activation of activator protein-1 and up-regulation of the heparin affin … C Polytarchou, M Hatziapostolou, E Papadimitriou Journal of Biological Chemistry 280 (49), 40428-40435, 2005 | 173 | 2005 |
A step-by-step microRNA guide to cancer development and metastasis GS Markopoulos, E Roupakia, M Tokamani, E Chavdoula, ... Cellular Oncology 40, 303-339, 2017 | 164 | 2017 |
An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state C Polytarchou, D Iliopoulos, K Struhl Proceedings of the National Academy of Sciences 109 (36), 14470-14475, 2012 | 159 | 2012 |
Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation C Polytarchou, D Iliopoulos, M Hatziapostolou, F Kottakis, I Maroulakou, ... Cancer research 71 (13), 4720-4731, 2011 | 150 | 2011 |
Neurotensin signaling activates microRNAs-21 and-155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors K Bakirtzi, M Hatziapostolou, I Karagiannides, C Polytarchou, S Jaeger, ... Gastroenterology 141 (5), 1749-1761. e1, 2011 | 147 | 2011 |
MicroRNA214 is associated with progression of ulcerative colitis, and inhibition reduces development of colitis and colitis-associated cancer in mice C Polytarchou, DW Hommes, T Palumbo, M Hatziapostolou, ... Gastroenterology 149 (4), 981-992. e11, 2015 | 141 | 2015 |
Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer I Sanidas, C Polytarchou, M Hatziapostolou, SA Ezell, F Kottakis, L Hu, ... Molecular cell 53 (4), 577-590, 2014 | 123 | 2014 |
A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation D Padua, S Mahurkar-Joshi, IKM Law, C Polytarchou, JP Vu, JR Pisegna, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 311 (3 …, 2016 | 119 | 2016 |
miRNAs link metabolic reprogramming to oncogenesis M Hatziapostolou, C Polytarchou, D Iliopoulos Trends in Endocrinology & Metabolism 24 (7), 361-373, 2013 | 97 | 2013 |
Soluble guanylyl cyclase activation promotes angiogenesis A Pyriochou, D Beis, V Koika, C Potytarchou, E Papadimitriou, Z Zhou, ... Journal of Pharmacology and Experimental Therapeutics 319 (2), 663-671, 2006 | 92 | 2006 |
The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY SA Ezell, C Polytarchou, M Hatziapostolou, A Guo, I Sanidas, T Bihani, ... Proceedings of the National Academy of Sciences 109 (10), E613-E621, 2012 | 85 | 2012 |
X‐rays modulate extracellular matrix in vivo E Giannopoulou, P Katsoris, M Hatziapostolou, D Kardamakis, E Kotsaki, ... International journal of cancer 94 (5), 690-698, 2001 | 78 | 2001 |
Antioxidants inhibit human endothelial cell functions through down-regulation of endothelial nitric oxide synthase activity C Polytarchou, E Papadimitriou European journal of pharmacology 510 (1-2), 31-38, 2005 | 77 | 2005 |
Assessment of circulating microRNAs for the diagnosis and disease activity evaluation in patients with ulcerative colitis by using the nanostring technology C Polytarchou, A Oikonomopoulos, S Mahurkar, A Touroutoglou, ... Inflammatory bowel diseases 21 (11), 2533-2539, 2015 | 74 | 2015 |