Alveolar regeneration through a Krt8+ transitional stem cell state that persists in human lung fibrosis M Strunz, LM Simon, M Ansari, JJ Kathiriya, I Angelidis, CH Mayr, ... Nature communications 11 (1), 3559, 2020 | 414 | 2020 |
The cellular and physiological basis for lung repair and regeneration: past, present, and future MC Basil, J Katzen, AE Engler, M Guo, MJ Herriges, JJ Kathiriya, ... Cell stem cell 26 (4), 482-502, 2020 | 281 | 2020 |
Distinct airway epithelial stem cells hide among club cells but mobilize to promote alveolar regeneration JJ Kathiriya, AN Brumwell, JR Jackson, X Tang, HA Chapman Cell stem cell 26 (3), 346-358. e4, 2020 | 163 | 2020 |
Human distal airways contain a multipotent secretory cell that can regenerate alveoli MC Basil, FL Cardenas-Diaz, JJ Kathiriya, MP Morley, J Carl, ... Nature 604 (7904), 120-126, 2022 | 156 | 2022 |
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells JJ Kathiriya, C Wang, M Zhou, A Brumwell, M Cassandras, CJ Le Saux, ... Nature cell biology 24 (1), 10-23, 2022 | 131 | 2022 |
BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors M Watanabe, YJ Kang, LM Davies, S Meghpara, K Lau, CY Chung, ... Journal of Neuroscience 32 (45), 15934-15945, 2012 | 82 | 2012 |
Gli1+ mesenchymal stromal cells form a pathological niche to promote airway progenitor metaplasia in the fibrotic lung M Cassandras, C Wang, J Kathiriya, T Tsukui, P Matatia, M Matthay, ... Nature cell biology 22 (11), 1295-1306, 2020 | 69 | 2020 |
Galectin-1 inhibition attenuates profibrotic signaling in hypoxia-induced pulmonary fibrosis JJ Kathiriya, N Nakra, J Nixon, PS Patel, V Vaghasiya, A Alhassani, Z Tian, ... Cell death discovery 3 (1), 1-13, 2017 | 50 | 2017 |
PTEN physically interacts with and regulates E2F1-mediated transcription in lung cancer P Malaney, E Palumbo, J Semidey-Hurtado, J Hardee, K Stanford, ... Cell Cycle 17 (8), 947-962, 2018 | 43 | 2018 |
Presence and utility of intrinsically disordered regions in kinases JJ Kathiriya, RR Pathak, E Clayman, B Xue, VN Uversky, V Davé Molecular bioSystems 10 (11), 2876-2888, 2014 | 34 | 2014 |
Longitudinal single cell transcriptomics reveals Krt8+ alveolar epithelial progenitors in lung regeneration M Strunz, LM Simon, M Ansari, LF Mattner, I Angelidis, CH Mayr, ... BioRxiv, 705244, 2019 | 30 | 2019 |
Human alveolar Type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells during alveolar repair JJ Kathiriya, C Wang, A Brumwell, M Cassandras, C Le Saux, P Wolters, ... BioRxiv, 2020.06. 06.136713, 2020 | 12 | 2020 |
An inflammatory switch for stem cell plasticity JJ Kathiriya, T Peng Nature cell biology 23 (9), 928-929, 2021 | 8 | 2021 |
BCL-2 Modulates IRE1α Activation to Attenuate Endoplasmic Reticulum Stress and Pulmonary Fibrosis. CJ Le Saux, TC Ho, AM Brumwell, JJ Kathiriya, Y Wei, JWB Hughes, ... American Journal of Respiratory Cell & Molecular Biology 70 (4), 2024 | 2 | 2024 |
Gli1+ mesenchymal stromal cells modulate epithelial metaplasia in lung fibrosis M Cassandras, C Wang, J Kathiriya, T Tsukui, P Matatia, M Matthay, ... bioRxiv, 841957, 2019 | 2 | 2019 |
Structural pliability adjacent to the kinase domain highlights contribution of FAK1 IDRs to cytoskeletal remodeling JJ Kathiriya, RR Pathak, A Bezginov, B Xue, VN Uversky, ERM Tillier, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (1), 43-54, 2017 | 2 | 2017 |
Data on evolution of intrinsically disordered regions of the human kinome and contribution of FAK1 IDRs to cytoskeletal remodeling JJ Kathiriya, RR Pathak, A Bezginov, B Xue, VN Uversky, ERM Tillier, ... Data in brief 10, 315-324, 2017 | 1 | 2017 |
Early Activation of Distal Lung Airway Progenitors Signifies a Role of Intermediate Filaments in Alveolar Regeneration JJ Kathiriya, K Zaw, S Dsouza, A Houser D108. SIGNALING PATHWAYS IN AIRWAY REGENERATION AND REPAIR, A7437-A7437, 2024 | | 2024 |
An Unexpected Role of Bcl2 in the Regulation of Unfolded Protein Responseand Fibrosis Resolution CT Le Saux, T Ho, A Brumwell, JJ Kathiriya, Y Wei, V Auyeung, ... AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 205, 2022 | | 2022 |
An Unexpected Role of Bcl2 in the Regulation of Unfolded Protein Responseand Fibrosis Resolution CT Jourdan Le Saux, TC Ho, A Brumwell, JJ Kathiriya, Y Wei, V Auyeung, ... D29. MECHANISMS IN LUNG INJURY, REPAIR, AND FIBROSIS, A5220-A5220, 2022 | | 2022 |