Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells A Rezania, JE Bruin, P Arora, A Rubin, I Batushansky, A Asadi, S O'dwyer, ... Nature biotechnology 32 (11), 1121-1133, 2014 | 1722 | 2014 |
Maturation of human embryonic stem cell–derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice A Rezania, JE Bruin, MJ Riedel, M Mojibian, A Asadi, J Xu, R Gauvin, ... Diabetes 61 (8), 2016-2029, 2012 | 730 | 2012 |
Circulating miR-375 as a biomarker of β-cell death and diabetes in mice S Erener, M Mojibian, JK Fox, HC Denroche, TJ Kieffer Endocrinology 154 (2), 603-608, 2013 | 227 | 2013 |
Reduced insulin production relieves endoplasmic reticulum stress and induces β cell proliferation M Szabat, MM Page, E Panzhinskiy, S Skovsř, M Mojibian, ... Cell metabolism 23 (1), 179-193, 2016 | 215 | 2016 |
Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells NAJ Dawson, C Lamarche, RE Hoeppli, P Bergqvist, VCW Fung, E McIver, ... JCI insight 4 (6), 2019 | 126 | 2019 |
Functional effects of chimeric antigen receptor co-receptor signaling domains in human regulatory T cells NAJ Dawson, I Rosado-Sánchez, GE Novakovsky, VCW Fung, Q Huang, ... Science Translational Medicine 12 (557), eaaz3866, 2020 | 121 | 2020 |
Treating diet-induced diabetes and obesity with human embryonic stem cell-derived pancreatic progenitor cells and antidiabetic drugs JE Bruin, N Saber, N Braun, JK Fox, M Mojibian, A Asadi, C Drohan, ... Stem cell reports 4 (4), 605-620, 2015 | 103 | 2015 |
Diabetes-specific HLA-DR–restricted proinflammatory T-cell response to wheat polypeptides in tissue transglutaminase antibody–negative patients with type 1 diabetes M Mojibian, H Chakir, DE Lefebvre, JA Crookshank, B Sonier, E Keely, ... Diabetes 58 (8), 1789-1796, 2009 | 98 | 2009 |
Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients A Sicard, C Lamarche, M Speck, M Wong, I Rosado-Sánchez, M Blois, ... American Journal of Transplantation 20 (6), 1562-1573, 2020 | 97 | 2020 |
T regulatory cell chemokine production mediates pathogenic T cell attraction and suppression SJ Patterson, AM Pesenacker, AY Wang, J Gillies, M Mojibian, K Morishita, ... The Journal of clinical investigation 126 (3), 1039-1051, 2016 | 80 | 2016 |
Promotion of autoimmune diabetes by cereal diet in the presence or absence of microbes associated with gut immune activation, regulatory imbalance, and altered cathelicidin … C Patrick, GS Wang, DE Lefebvre, JA Crookshank, B Sonier, C Eberhard, ... Diabetes 62 (6), 2036-2047, 2013 | 74 | 2013 |
Tailoring the homing capacity of human Tregs for directed migration to sites of Th1-inflammation or intestinal regions RE Hoeppli, KN MacDonald, P Leclair, VCW Fung, M Mojibian, J Gillies, ... American journal of transplantation 19 (1), 62-76, 2019 | 70 | 2019 |
Implanted islets in the anterior chamber of the eye are prone to autoimmune attack in a mouse model of diabetes M Mojibian, B Harder, A Hurlburt, JE Bruin, A Asadi, TJ Kieffer Diabetologia 56, 2213-2221, 2013 | 53 | 2013 |
Hypothyroidism impairs human stem cell–derived pancreatic progenitor cell maturation in mice JE Bruin, N Saber, S O’Dwyer, JK Fox, M Mojibian, P Arora, A Rezania, ... Diabetes 65 (5), 1297-1309, 2016 | 43 | 2016 |
T reg–specific insulin receptor deletion prevents diet-induced and age-associated metabolic syndrome D Wu, CK Wong, JM Han, PC Orban, Q Huang, J Gillies, M Mojibian, ... Journal of Experimental Medicine 217 (8), e20191542, 2020 | 40 | 2020 |
Preclinical assessment of antigen-specific chimeric antigen receptor regulatory T cells for use in solid organ transplantation E Proics, M David, M Mojibian, M Speck, N Lounnas-Mourey, ... Gene Therapy 30 (3), 309-322, 2023 | 39 | 2023 |
An exploration of Glo‐3A antibody levels in children at increased risk for type 1 diabetes mellitus M Simpson, M Mojibian, K Barriga, FW Scott, A Fasano, M Rewers, ... Pediatric diabetes 10 (8), 563-572, 2009 | 37 | 2009 |
Glucagon receptor gene deletion in insulin knockout mice modestly reduces blood glucose and ketones but does not promote survival UH Neumann, JSS Ho, M Mojibian, SD Covey, MJ Charron, TJ Kieffer Molecular metabolism 5 (8), 731-736, 2016 | 35 | 2016 |
IL-12Rβ2-deficient mice of a genetically resistant background are susceptible to Leishmania major infection and develop a parasite-specific Th2 immune response H Chakir, A Campos-Neto, M Mojibian, JR Webb Microbes and infection 5 (4), 241-249, 2003 | 35 | 2003 |
Insulin knockout mice have extended survival but volatile blood glucose levels on leptin therapy UH Neumann, HC Denroche, M Mojibian, SD Covey, TJ Kieffer Endocrinology 157 (3), 1007-1012, 2016 | 28 | 2016 |