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Akshatha Ganne
Akshatha Ganne
Bioinformatics and Computational Biology, UALR/UAMS
Verified email at uams.edu - Homepage
Title
Cited by
Cited by
Year
Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration
S Ayyadevara, A Ganne, M Balasubramaniam, RJ Shmookler Reis
Metabolic Brain Disease 37 (1), 147-152, 2022
242022
“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation
RJ Shmookler Reis, R Atluri, M Balasubramaniam, J Johnson, A Ganne, ...
Aging Cell 20 (5), e13326, 2021
192021
Glial fibrillary acidic protein: a biomarker and drug target for alzheimer’s disease
A Ganne, M Balasubramaniam, WST Griffin, RJ Shmookler Reis, ...
Pharmaceutics 14 (7), 1354, 2022
172022
A novel microtubule-binding drug attenuates and reverses protein aggregation in animal models of Alzheimer’s Disease
S Kakraba, S Ayyadevara, NR Penthala, M Balasubramaniam, A Ganne, ...
Frontiers in Molecular Neuroscience 12, 310, 2019
152019
Aggregate interactome based on protein cross-linking interfaces predicts drug targets to limit aggregation in neurodegenerative diseases
M Balasubramaniam, S Ayyadevara, A Ganne, S Kakraba, NR Penthala, ...
Iscience 20, 248-264, 2019
132019
Functional assessments through novel proteomics approaches: Application to insulin/IGF signaling in neurodegenerative disease'
S Ayyadevara, A Ganne, RD Hendrix, M Balasubramaniam, RJS Reis, ...
Journal of neuroscience methods 319, 40-46, 2019
82019
Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase
M Balasubramaniam, RJS Reis, S Ayyadevara, X Wang, A Ganne, ...
Mechanisms of Ageing and Development 166, 55-63, 2017
52017
In silico analysis of TUBA4A mutations in Amyotrophic Lateral Sclerosis to define mechanisms of microtubule disintegration
A Ganne, M Balasubramaniam, H Ayyadevara, L Kiaei, ...
Scientific Reports 13 (1), 2096, 2023
42023
Machine-learning analysis of intrinsically disordered proteins identifies key factors that contribute to neurodegeneration-related aggregation
A Ganne, M Balasubramaniam, S Ayyadevara, RJ Shmookler Reis
Frontiers in Aging Neuroscience 14, 938117, 2022
32022
Protein homeostasis in the aged and diseased heart
N Mainali, S Ayyadevara, A Ganne, RJS Reis, JL Mehta
The journal of cardiovascular aging 3 (2), 2023
22023
Myocardial infarction elevates endoplasmic reticulum stress and protein aggregation in heart as well as brain
N Mainali, X Li, X Wang, M Balasubramaniam, A Ganne, R Kore, ...
Molecular and Cellular Biochemistry, 1-13, 2023
12023
Alzheimer’s-specific brain amyloid interactome: Neural-network analysis of intra-aggregate crosslinking identifies novel drug targets
M Balasubramaniam, A Ganne, N Mainali, S Pahal, S Ayyadevara, ...
Iscience 27 (1), 2024
2024
Rescue of ApoE4-related lysosomal autophagic failure in Alzheimer’s disease by targeted small molecules
M Balasubramaniam, J Narasimhappagari, L Liu, A Ganne, S Ayyadevara, ...
Communications Biology 7 (1), 60, 2024
2024
Intrinsic Disorder in Proteins Associated with Neurodegenerative Diseases
A Ganne
University of Arkansas at Little Rock, 2021
2021
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