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Chad D. Brown
Chad D. Brown
University of Washington, Merck, intervet
Verified email at merck.com
Title
Cited by
Cited by
Year
Mechanism of dissolution-induced nanoparticle formation from a copovidone-based amorphous solid dispersion
P Harmon, K Galipeau, W Xu, C Brown, WP Wuelfing
Molecular pharmaceutics 13 (5), 1467-1481, 2016
1142016
Adhesive protein interactions with chitosan: Consequences for valve endothelial cell growth on tissue‐engineering materials
JL Cuy, BL Beckstead, CD Brown, AS Hoffman, CM Giachelli
Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2003
1062003
Molecular interactions in posaconazole amorphous solid dispersions from two-dimensional solid-state NMR spectroscopy
X Lu, C Huang, MB Lowinger, F Yang, W Xu, CD Brown, D Hesk, ...
Molecular pharmaceutics 16 (6), 2579-2589, 2019
752019
Rheology guided rational selection of processing temperature to prepare copovidone–nifedipine amorphous solid dispersions via hot melt extrusion (HME)
F Yang, Y Su, J Zhang, J DiNunzio, A Leone, C Huang, CD Brown
Molecular pharmaceutics 13 (10), 3494-3505, 2016
632016
Release of PEGylated granulocyte-macrophage colony-stimulating factor from chitosan/glycerol films
CD Brown, L Kreilgaard, M Nakakura, N Caram-Lelham, DK Pettit, ...
Journal of controlled release 72 (1-3), 35-46, 2001
582001
Rheological and solid-state NMR assessments of copovidone/clotrimazole model solid dispersions
F Yang, Y Su, L Zhu, CD Brown, LA Rosen, KJ Rosenberg
International journal of pharmaceutics 500 (1-2), 20-31, 2016
362016
Hot-melt extrusion for solid dispersions: composition and design considerations
C Brown, J DiNunzio, M Eglesia, S Forster, M Lamm, M Lowinger, ...
Amorphous solid dispersions: theory and practice, 197-230, 2014
352014
Impact of polymer type on bioperformance and physical stability of hot melt extruded formulations of a poorly water soluble drug
A Mitra, L Li, P Marsac, B Marks, Z Liu, C Brown
International Journal of Pharmaceutics 505 (1-2), 107-114, 2016
312016
Hot-melt extrusion: the process-product-performance interplay
N Boersen, C Brown, J DiNunzio, D Johnson, P Marsac, R Meyer, ...
Discovering and Developing Molecules with Optimal Drug-Like Properties, 345-381, 2014
152014
Semi-interpenetrating network of poly (ethylene glycol) and poly (D, L-lactide) for the controlled delivery of protein drugs
CD Brown, PS Stayton, AS Hoffman
Journal of Biomaterials Science, Polymer Edition 16 (2), 189-201, 2005
152005
Modification of natural polymer: Chitosan
CD Brown, AS Hoffman
Methods of tissue engineering. Academic Press, California, 565-574, 2002
142002
HME for solid dispersions: scale-up and late-stage development
C Brown, J DiNunzio, M Eglesia, S Forster, M Lamm, M Lowinger, ...
Amorphous Solid Dispersions: Theory and Practice, 231-260, 2014
132014
Probing the molecular-level interactions in an active pharmaceutical ingredient (API)-polymer dispersion and the resulting impact on drug product formulation
F Yang, Y Su, J Small, C Huang, GE Martin, AM Farrington, J DiNunzio, ...
Pharmaceutical Research 37, 1-16, 2020
112020
Effect of TPGS surfactant on dissolution sensitivity of a poorly water-soluble drug using high-shear wet granulation
S Sotthivirat, R Ramesh, W Wasylaschuk, C Bottone, B Xia, J Stellabott, ...
Powder Technology 375, 302-309, 2020
92020
Evaluation of foaming of pharmaceutical polymers by CO2 and N2 to enable drug products
CD Brown, N Faridi, CA McKelvey, JH Suwardie, L Zhu, MW Young, ...
69th Annual Technical Conference of the Society of Plastics Engineers 2011 …, 2011
72011
Tablet formulation for CGRP active compounds
MA Johnson, LR Allain, WM Eickhoff, CB Ikeda, CD Brown, FJ Flanagan, ...
US Patent 10,117,836, 2018
62018
Solubilizing temperature of crystalline drug in polymer carrier: A rheological investigation on a posaconazole-copovidone system with low drug load
F Yang, Y Su, CD Brown, J DiNunzio
European Journal of Pharmaceutics and Biopharmaceutics 164, 28-35, 2021
42021
Fixed-dose combinations of antiviral compounds
D Harris, J DiNunzio, WA Marinaro, S Sotthivirat, CD Brown, ...
US Patent App. 15/750,056, 2018
42018
Novel disintegration systems for pharmaceutical dosage forms
MJ Marota, CD Brown, CB Ikeda, MA Johnson, H Xi, W Xu, L Cai
US Patent App. 15/116,826, 2016
42016
Melt extrusion: pharmaceutical applications
J DiNunzio, S Forster, C Brown
Handbook of encapsulation and controlled release, 1127-1150, 2016
42016
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