Mechanism of dissolution-induced nanoparticle formation from a copovidone-based amorphous solid dispersion P Harmon, K Galipeau, W Xu, C Brown, WP Wuelfing Molecular pharmaceutics 13 (5), 1467-1481, 2016 | 114 | 2016 |
Adhesive protein interactions with chitosan: Consequences for valve endothelial cell growth on tissue‐engineering materials JL Cuy, BL Beckstead, CD Brown, AS Hoffman, CM Giachelli Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2003 | 106 | 2003 |
Molecular interactions in posaconazole amorphous solid dispersions from two-dimensional solid-state NMR spectroscopy X Lu, C Huang, MB Lowinger, F Yang, W Xu, CD Brown, D Hesk, ... Molecular pharmaceutics 16 (6), 2579-2589, 2019 | 75 | 2019 |
Rheology guided rational selection of processing temperature to prepare copovidone–nifedipine amorphous solid dispersions via hot melt extrusion (HME) F Yang, Y Su, J Zhang, J DiNunzio, A Leone, C Huang, CD Brown Molecular pharmaceutics 13 (10), 3494-3505, 2016 | 63 | 2016 |
Release of PEGylated granulocyte-macrophage colony-stimulating factor from chitosan/glycerol films CD Brown, L Kreilgaard, M Nakakura, N Caram-Lelham, DK Pettit, ... Journal of controlled release 72 (1-3), 35-46, 2001 | 58 | 2001 |
Rheological and solid-state NMR assessments of copovidone/clotrimazole model solid dispersions F Yang, Y Su, L Zhu, CD Brown, LA Rosen, KJ Rosenberg International journal of pharmaceutics 500 (1-2), 20-31, 2016 | 36 | 2016 |
Hot-melt extrusion for solid dispersions: composition and design considerations C Brown, J DiNunzio, M Eglesia, S Forster, M Lamm, M Lowinger, ... Amorphous solid dispersions: theory and practice, 197-230, 2014 | 35 | 2014 |
Impact of polymer type on bioperformance and physical stability of hot melt extruded formulations of a poorly water soluble drug A Mitra, L Li, P Marsac, B Marks, Z Liu, C Brown International Journal of Pharmaceutics 505 (1-2), 107-114, 2016 | 31 | 2016 |
Hot-melt extrusion: the process-product-performance interplay N Boersen, C Brown, J DiNunzio, D Johnson, P Marsac, R Meyer, ... Discovering and Developing Molecules with Optimal Drug-Like Properties, 345-381, 2014 | 15 | 2014 |
Semi-interpenetrating network of poly (ethylene glycol) and poly (D, L-lactide) for the controlled delivery of protein drugs CD Brown, PS Stayton, AS Hoffman Journal of Biomaterials Science, Polymer Edition 16 (2), 189-201, 2005 | 15 | 2005 |
Modification of natural polymer: Chitosan CD Brown, AS Hoffman Methods of tissue engineering. Academic Press, California, 565-574, 2002 | 14 | 2002 |
HME for solid dispersions: scale-up and late-stage development C Brown, J DiNunzio, M Eglesia, S Forster, M Lamm, M Lowinger, ... Amorphous Solid Dispersions: Theory and Practice, 231-260, 2014 | 13 | 2014 |
Probing the molecular-level interactions in an active pharmaceutical ingredient (API)-polymer dispersion and the resulting impact on drug product formulation F Yang, Y Su, J Small, C Huang, GE Martin, AM Farrington, J DiNunzio, ... Pharmaceutical Research 37, 1-16, 2020 | 11 | 2020 |
Effect of TPGS surfactant on dissolution sensitivity of a poorly water-soluble drug using high-shear wet granulation S Sotthivirat, R Ramesh, W Wasylaschuk, C Bottone, B Xia, J Stellabott, ... Powder Technology 375, 302-309, 2020 | 9 | 2020 |
Evaluation of foaming of pharmaceutical polymers by CO2 and N2 to enable drug products CD Brown, N Faridi, CA McKelvey, JH Suwardie, L Zhu, MW Young, ... 69th Annual Technical Conference of the Society of Plastics Engineers 2011 …, 2011 | 7 | 2011 |
Tablet formulation for CGRP active compounds MA Johnson, LR Allain, WM Eickhoff, CB Ikeda, CD Brown, FJ Flanagan, ... US Patent 10,117,836, 2018 | 6 | 2018 |
Solubilizing temperature of crystalline drug in polymer carrier: A rheological investigation on a posaconazole-copovidone system with low drug load F Yang, Y Su, CD Brown, J DiNunzio European Journal of Pharmaceutics and Biopharmaceutics 164, 28-35, 2021 | 4 | 2021 |
Fixed-dose combinations of antiviral compounds D Harris, J DiNunzio, WA Marinaro, S Sotthivirat, CD Brown, ... US Patent App. 15/750,056, 2018 | 4 | 2018 |
Novel disintegration systems for pharmaceutical dosage forms MJ Marota, CD Brown, CB Ikeda, MA Johnson, H Xi, W Xu, L Cai US Patent App. 15/116,826, 2016 | 4 | 2016 |
Melt extrusion: pharmaceutical applications J DiNunzio, S Forster, C Brown Handbook of encapsulation and controlled release, 1127-1150, 2016 | 4 | 2016 |