hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase H Vaziri, SK Dessain, EN Eaton, SI Imai, RA Frye, TK Pandita, L Guarente, ... Cell 107 (2), 149-159, 2001 | 3358 | 2001 |
c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability O Vafa, M Wade, S Kern, M Beeche, TK Pandita, GM Hampton, GM Wahl Molecular cell 9 (5), 1031-1044, 2002 | 1070 | 2002 |
High frequency of hypermethylation at the 14-3-3 σ locus leads to gene silencing in breast cancer AT Ferguson, E Evron, CB Umbricht, TK Pandita, TA Chan, H Hermeking, ... Proceedings of the National Academy of Sciences 97 (11), 6049-6054, 2000 | 581 | 2000 |
ATM stabilizes DNA double-strand-break complexes during V (D) J recombination AL Bredemeyer, GG Sharma, CY Huang, BA Helmink, LM Walker, ... Nature 442 (7101), 466-470, 2006 | 435 | 2006 |
Lack of PTEN sequesters CHK1 and initiates genetic instability J Puc, M Keniry, HS Li, TK Pandita, AD Choudhury, L Memeo, ... Cancer cell 7 (2), 193-204, 2005 | 408 | 2005 |
ATM functions at the peroxisome to induce pexophagy in response to ROS J Zhang, DN Tripathi, J Jing, A Alexander, J Kim, RT Powell, R Dere, ... Nature cell biology 17 (10), 1259-1269, 2015 | 400 | 2015 |
Rad52 inactivation is synthetically lethal with BRCA2 deficiency Z Feng, SP Scott, W Bussen, GG Sharma, G Guo, TK Pandita, SN Powell Proceedings of the National Academy of Sciences 108 (2), 686-691, 2011 | 397 | 2011 |
MOF and histone H4 acetylation at lysine 16 are critical for DNA damage response and double-strand break repair GG Sharma, S So, A Gupta, R Kumar, C Cayrou, N Avvakumov, U Bhadra, ... Molecular and cellular biology 30 (14), 3582-3595, 2010 | 352 | 2010 |
hTERT associates with human telomeres and enhances genomic stability and DNA repair GG Sharma, A Gupta, H Wang, H Scherthan, S Dhar, V Gandhi, G Iliakis, ... Oncogene 22 (1), 131-146, 2003 | 347 | 2003 |
Genomic instability and enhanced radiosensitivity in Hsp70. 1-and Hsp70. 3-deficient mice CR Hunt, DJ Dix, GG Sharma, RK Pandita, A Gupta, M Funk, TK Pandita Molecular and cellular biology, 2004 | 300 | 2004 |
Involvement of human MOF in ATM function A Gupta, GG Sharma, CSH Young, M Agarwal, ER Smith, TT Paull, ... Molecular and cellular biology 25 (12), 5292-5305, 2005 | 282 | 2005 |
Single-stranded DNA-binding protein hSSB1 is critical for genomic stability DJ Richard, E Bolderson, L Cubeddu, RIM Wadsworth, K Savage, ... Nature 453 (7195), 677-681, 2008 | 280 | 2008 |
The TIP60 complex regulates bivalent chromatin recognition by 53BP1 through direct H4K20me binding and H2AK15 acetylation K Jacquet, A Fradet-Turcotte, N Avvakumov, JP Lambert, C Roques, ... Molecular cell 62 (3), 409-421, 2016 | 252 | 2016 |
The Mammalian Ortholog of Drosophila MOF That Acetylates Histone H4 Lysine 16 Is Essential for Embryogenesis and Oncogenesis A Gupta, TG Guerin-Peyrou, GG Sharma, C Park, M Agarwal, RK Ganju, ... Molecular and cellular biology 28 (1), 397-409, 2008 | 245 | 2008 |
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks E Bolderson, N Tomimatsu, DJ Richard, D Boucher, R Kumar, TK Pandita, ... Nucleic acids research 38 (6), 1821-1831, 2010 | 224 | 2010 |
ATM function and telomere stability TK Pandita Oncogene 21 (4), 611-618, 2002 | 223 | 2002 |
Regulation of the hTERT telomerase catalytic subunit by the c-Abl tyrosine kinase S Kharbanda, V Kumar, S Dhar, P Pandey, C Chen, P Majumder, ... Current Biology 10 (10), 568-575, 2000 | 222 | 2000 |
Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells TK Pandita, S Pathak, CR Geard Cytogenetic and Genome Research 71 (1), 86-93, 1995 | 220 | 1995 |
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function W Fu, M Killen, C Culmsee, S Dhar, TK Pandita, MP Mattson Journal of Molecular Neuroscience 14, 3-15, 2000 | 216 | 2000 |
Fragments of ATM which have dominant-negative or complementing activity SE Morgan, C Lovly, TK Pandita, Y Shiloh, MB Kastan Molecular and cellular biology, 1997 | 212 | 1997 |