|Drug penetration in solid tumours|
AI Minchinton, IF Tannock
Nature Reviews Cancer 6 (8), 583-592, 2006
|Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors|
Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ...
Cancer research 71 (9), 3364-3376, 2011
|SHIP represses the generation of alternatively activated macrophages|
MJ Rauh, V Ho, C Pereira, A Sham, LM Sly, V Lam, L Huxham, ...
Immunity 23 (4), 361-374, 2005
|Translational activation of HIF1α by YB-1 promotes sarcoma metastasis|
AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ...
Cancer cell 27 (5), 682-697, 2015
|Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition|
C Daly, A Eichten, C Castanaro, E Pasnikowski, A Adler, AS Lalani, ...
Cancer research 73 (1), 108-118, 2013
|Limited tissue penetration of taxanes: a mechanism for resistance in solid tumors|
AH Kyle, LA Huxham, DM Yeoman, AI Minchinton
Clinical Cancer Research 13 (9), 2804-2810, 2007
|A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation|
VW Ho, K Leung, A Hsu, B Luk, J Lai, SY Shen, AI Minchinton, ...
Cancer research 71 (13), 4484-4493, 2011
|Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase|
ACY Chang, YX Fu, VC Garside, K Niessen, L Chang, M Fuller, A Setiadi, ...
Developmental cell 21 (2), 288-300, 2011
|Direct visualization of heterogeneous extravascular distribution of trastuzumab in human epidermal growth factor receptor type 2 overexpressing xenografts|
JHE Baker, KE Lindquist, LA Huxham, AH Kyle, JT Sy, AI Minchinton
Clinical Cancer Research 14 (7), 2171-2179, 2008
|The prognostic impact of CD163-positive macrophages in follicular lymphoma: a study from the BC cancer agency and the lymphoma study association|
R Kridel, L Xerri, B Gelas-Dore, K Tan, P Feugier, A Vawda, D Canioni, ...
Clinical Cancer Research 21 (15), 3428-3435, 2015
|The clinical testing of Ro 03-8799—pharmacokinetics, toxicology, tissue and tumor concentrations|
MI Saunders, PJ Anderson, MH Bennett, S Dische, A Minchinton, ...
International Journal of Radiation Oncology* Biology* Physics 10 (9), 1759-1763, 1984
|Characterization of three-dimensional tissue cultures using electrical impedance spectroscopy|
AH Kyle, CTO Chan, AI Minchinton
Biophysical journal 76 (5), 2640-2648, 1999
|Targeting hypoxia-induced carbonic anhydrase IX enhances immune-checkpoint blockade locally and systemically|
SC Chafe, PC McDonald, S Saberi, O Nemirovsky, G Venkateswaran, ...
Cancer immunology research 7 (7), 1064-1078, 2019
|The effect of thalidomide on experimental tumors and metastases|
AI Minchinton, KH Fryer, KR Wendt, KA Clow, MMM Hayes
Anti-Cancer Drugs 7 (3), 339-343, 1996
|Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK)|
LA Edwards, J Woo, LA Huxham, M Verreault, WH Dragowska, G Chiu, ...
Molecular cancer therapeutics 7 (1), 59-70, 2008
|Microregional effects of gemcitabine in HCT-116 xenografts|
LA Huxham, AH Kyle, JHE Baker, LK Nykilchuk, AI Minchinton
Cancer research 64 (18), 6537-6541, 2004
|Measurement of delivery and metabolism of tirapazamine to tumour tissue using the multilayered cell culture model|
AH Kyle, AI Minchinton
Cancer chemotherapy and pharmacology 43, 213-220, 1999
|Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture|
AH Kyle, LA Huxham, ASJ Chiam, DH Sim, AI Minchinton
Cancer research 64 (17), 6304-6309, 2004
|Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma|
KKY Cham, JHE Baker, KS Takhar, JA Flexman, MQ Wong, DA Owen, ...
British journal of cancer 103 (1), 52-60, 2010
|Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling|
L Chang, M Noseda, M Higginson, M Ly, A Patenaude, M Fuller, AH Kyle, ...
Proceedings of the National Academy of Sciences 109 (18), 6993-6998, 2012