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Andrew Minchinton
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Drug penetration in solid tumours
AI Minchinton, IF Tannock
Nature Reviews Cancer 6 (8), 583-592, 2006
28152006
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ...
Cancer research 71 (9), 3364-3376, 2011
6822011
SHIP represses the generation of alternatively activated macrophages
MJ Rauh, V Ho, C Pereira, A Sham, LM Sly, V Lam, L Huxham, ...
Immunity 23 (4), 361-374, 2005
3172005
Translational activation of HIF1α by YB-1 promotes sarcoma metastasis
AM El-Naggar, CJ Veinotte, H Cheng, TGP Grunewald, GL Negri, ...
Cancer cell 27 (5), 682-697, 2015
2722015
Angiopoietin-2 functions as a Tie2 agonist in tumor models, where it limits the effects of VEGF inhibition
C Daly, A Eichten, C Castanaro, E Pasnikowski, A Adler, AS Lalani, ...
Cancer research 73 (1), 108-118, 2013
2312013
Limited tissue penetration of taxanes: a mechanism for resistance in solid tumors
AH Kyle, LA Huxham, DM Yeoman, AI Minchinton
Clinical Cancer Research 13 (9), 2804-2810, 2007
2002007
A Low Carbohydrate, High Protein Diet Slows Tumor Growth and Prevents Cancer InitiationLow Carbohydrate, High Protein Diets Slow Tumor Growth
VW Ho, K Leung, A Hsu, B Luk, J Lai, SY Shen, AI Minchinton, ...
Cancer research 71 (13), 4484-4493, 2011
1732011
Notch initiates the endothelial-to-mesenchymal transition in the atrioventricular canal through autocrine activation of soluble guanylyl cyclase
ACY Chang, YX Fu, VC Garside, K Niessen, L Chang, M Fuller, A Setiadi, ...
Developmental cell 21 (2), 288-300, 2011
1562011
Direct visualization of heterogeneous extravascular distribution of trastuzumab in human epidermal growth factor receptor type 2 overexpressing xenografts
JHE Baker, KE Lindquist, LA Huxham, AH Kyle, JT Sy, AI Minchinton
Clinical Cancer Research 14 (7), 2171-2179, 2008
1262008
Characterization of three-dimensional tissue cultures using electrical impedance spectroscopy
AH Kyle, CTO Chan, AI Minchinton
Biophysical journal 76 (5), 2640-2648, 1999
1211999
The clinical testing of Ro 03-8799—pharmacokinetics, toxicology, tissue and tumor concentrations
MI Saunders, PJ Anderson, MH Bennett, S Dische, A Minchinton, ...
International Journal of Radiation Oncology* Biology* Physics 10 (9), 1759-1763, 1984
1211984
The Prognostic Impact of CD163-Positive Macrophages in Follicular Lymphoma: A Study from the BC Cancer Agency and the Lymphoma Study AssociationFollicular Lymphoma–Associated …
R Kridel, L Xerri, B Gelas-Dore, K Tan, P Feugier, A Vawda, D Canioni, ...
Clinical Cancer Research 21 (15), 3428-3435, 2015
1142015
The effect of thalidomide on experimental tumors and metastases.
AI Minchinton, KH Fryer, KR Wendt, KA Clow, MM Hayes
Anti-Cancer Drugs 7 (3), 339-343, 1996
1061996
Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK)
LA Edwards, J Woo, LA Huxham, M Verreault, WH Dragowska, G Chiu, ...
Molecular cancer therapeutics 7 (1), 59-70, 2008
1012008
Microregional effects of gemcitabine in HCT-116 xenografts
LA Huxham, AH Kyle, JHE Baker, LK Nykilchuk, AI Minchinton
Cancer research 64 (18), 6537-6541, 2004
942004
Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and SystemicallyCAIX Inhibition Enhances Immune-Checkpoint Blockade
SC Chafe, PC McDonald, S Saberi, O Nemirovsky, G Venkateswaran, ...
Cancer immunology research 7 (7), 1064-1078, 2019
912019
Direct assessment of drug penetration into tissue using a novel application of three-dimensional cell culture
AH Kyle, LA Huxham, ASJ Chiam, DH Sim, AI Minchinton
Cancer research 64 (17), 6304-6309, 2004
912004
Measurement of delivery and metabolism of tirapazamine to tumour tissue using the multilayered cell culture model
AH Kyle, AI Minchinton
Cancer chemotherapy and pharmacology 43, 213-220, 1999
881999
Differentiation of vascular smooth muscle cells from local precursors during embryonic and adult arteriogenesis requires Notch signaling
L Chang, M Noseda, M Higginson, M Ly, A Patenaude, M Fuller, AH Kyle, ...
Proceedings of the National Academy of Sciences 109 (18), 6993-6998, 2012
802012
Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma
KKY Cham, JHE Baker, KS Takhar, JA Flexman, MQ Wong, DA Owen, ...
British journal of cancer 103 (1), 52-60, 2010
802010
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