David Goode
David Goode
Group Leader, Computational Biology, Peter MacCallum Cancer Centre
Verified email at
Cited by
Cited by
Identifying a high fraction of the human genome to be under selective constraint using GERP++
EV Davydov, DL Goode, M Sirota, GM Cooper, A Sidow, S Batzoglou
PLoS Comput Biol 6 (12), e1001025, 2010
Dissecting virulence: systematic and functional analyses of a pathogenicity island
W Deng, JL Puente, S Gruenheid, Y Li, BA Vallance, A Vázquez, J Barba, ...
Proceedings of the National Academy of Sciences 101 (10), 3597-3602, 2004
Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157: H7
S Gruenheid, I Sekirov, NA Thomas, W Deng, P O'Donnell, D Goode, Y Li, ...
Molecular microbiology 51 (5), 1233-1249, 2004
The origin, evolution, and functional impact of short insertion–deletion variants identified in 179 human genomes
SB Montgomery, DL Goode, E Kvikstad, CA Albers, ZD Zhang, XJ Mu, ...
Genome research 23 (5), 749-761, 2013
Monogenic and polygenic determinants of sarcoma risk: an international genetic study
ML Ballinger, DL Goode, I Ray-Coquard, PA James, G Mitchell, ...
The Lancet Oncology 17 (9), 1261-1271, 2016
Single-nucleotide evolutionary constraint scores highlight disease-causing mutations
GM Cooper, DL Goode, SB Ng, A Sidow, MJ Bamshad, J Shendure, ...
Nature methods 7 (4), 250-251, 2010
Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors
AS Trigos, RB Pearson, AT Papenfuss, DL Goode
Proceedings of the National Academy of Sciences 114 (24), 6406-6411, 2017
Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex
K Belov, JE Deakin, AT Papenfuss, ML Baker, SD Melman, HV Siddle, ...
PLoS biology 4 (3), e46, 2006
Loss of heterozygosity: what is it good for?
GL Ryland, MA Doyle, D Goode, SE Boyle, DYH Choong, SM Rowley, J Li, ...
BMC medical genomics 8 (1), 45, 2015
Targeting enhancer switching overcomes non-genetic drug resistance in acute myeloid leukaemia
CC Bell, KA Fennell, YC Chan, F Rambow, MM Yeung, D Vassiliadis, ...
Nature communications 10 (1), 2723, 2019
How the evolution of multicellularity set the stage for cancer
AS Trigos, RB Pearson, AT Papenfuss, DL Goode
British journal of cancer, 2018
The H3K4-Methyl Epigenome Regulates Leukemia Stem Cell Oncogenic Potential
SHK Wong, DL Goode, M Iwasaki, MC Wei, HP Kuo, L Zhu, ...
Cancer cell, 2015
Proteomic analysis of the intestinal epithelial cell response to enteropathogenic Escherichia coli
PR Hardwidge, I Rodriguez-Escudero, D Goode, S Donohoe, J Eng, ...
Journal of Biological Chemistry 279 (19), 20127-20136, 2004
SseK1 and SseK2 are novel translocated proteins of Salmonella enterica serovar typhimurium
SLK Choy, EC Boyle, O Gal-Mor, DL Goode, Y Valdez, BA Vallance, ...
Infection and immunity 72 (9), 5115-5125, 2004
Patient-derived models of abiraterone-and enzalutamide-resistant prostate cancer reveal sensitivity to ribosome-directed therapy
MG Lawrence, D Obinata, S Sandhu, LA Selth, SQ Wong, LH Porter, ...
European urology 74 (5), 562-572, 2018
ArrayPipe: a flexible processing pipeline for microarray data
K Hokamp, FM Roche, M Acab, ME Rousseau, B Kuo, D Goode, ...
Nucleic acids research 32 (suppl 2), W457-W459, 2004
Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes
DL Goode, GM Cooper, J Schmutz, M Dickson, E Gonzales, M Tsai, ...
Genome research 20 (3), 301-310, 2010
MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer
A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ...
Science 368 (6495), 1127-1131, 2020
Salmonella phage ST64B encodes a member of the SseK/NleB effector family
NF Brown, BK Coombes, JL Bishop, ME Wickham, MJ Lowden, O Gal-Mor, ...
PloS one 6 (3), e17824, 2011
High Frequency of Germline TP53 Mutations in a Prospective Adult-Onset Sarcoma Cohort
G Mitchell, ML Ballinger, S Wong, C Hewitt, P James, MA Young, ...
PloS one 8 (7), e69026, 2013
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