Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity G Di Conza, CH Tsai, H Gallart-Ayala, YR Yu, F Franco, L Zaffalon, X Xie, ... Nature immunology 22 (11), 1403-1415, 2021 | 84 | 2021 |
PERK is a critical metabolic hub for immunosuppressive function in macrophages LN Raines, H Zhao, Y Wang, HY Chen, H Gallart-Ayala, PC Hsueh, ... Nature immunology 23 (3), 431-445, 2022 | 79 | 2022 |
Carbohydrate and amino acid metabolism as hallmarks for innate immune cell activation and function H Zhao, LN Raines, SCC Huang Cells 9 (3), 562, 2020 | 30 | 2020 |
Development of a forward-oriented therapeutic lentiviral vector for hemoglobin disorders N Uchida, MM Hsieh, L Raines, JJ Haro-Mora, S Demirci, AC Bonifacino, ... Nature Communications 10 (1), 4479, 2019 | 25 | 2019 |
Evaluating biological activity of compounds by transcription factor activity profiling A Medvedev, M Moeser, L Medvedeva, E Martsen, A Granick, L Raines, ... Science Advances 4 (9), eaar4666, 2018 | 17 | 2018 |
Serum-free erythroid differentiation for efficient genetic modification and high-level adult hemoglobin production N Uchida, S Demirci, JJ Haro-Mora, A Fujita, LN Raines, MM Hsieh, ... Molecular Therapy-Methods & Clinical Development 9, 247-256, 2018 | 14 | 2018 |
Total body irradiation must be delivered at high dose for efficient engraftment and tolerance in a rhesus stem cell gene therapy model N Uchida, RP Weitzel, A Shvygin, LP Skala, L Raines, AC Bonifacino, ... Molecular Therapy-Methods & Clinical Development 3, 2016 | 11 | 2016 |
High-level embryonic globin production with efficient erythroid differentiation from a K562 erythroleukemia cell line N Uchida, JJ Haro-Mora, S Demirci, A Fujita, L Raines, MM Hsieh, ... Experimental hematology 62, 7-16. e1, 2018 | 10 | 2018 |
Is glucose the scapegoat for tumor evasion? LN Raines, SCC Huang Cancer Cell 39 (7), 907-909, 2021 | 7 | 2021 |
Molecular chaperones: Molecular assembly line brings metabolism and immunity in shape H Zhao, LN Raines, SCC Huang Metabolites 10 (10), 394, 2020 | 7 | 2020 |
RNA trans-splicing targeting endogenous β-globin pre-messenger RNA in human erythroid cells N Uchida, KN Washington, B Mozer, C Platner, J Ballantine, LP Skala, ... Human gene therapy methods 28 (2), 91-99, 2017 | 7 | 2017 |
Intrabone transplantation of CD34+ cells with optimized delivery does not enhance engraftment in a rhesus macaque model K Stringaris, RF Hoyt Jr, JK Davidson-Moncada, JM Pantin, JF Tisdale, ... Blood Advances 4 (24), 6148-6156, 2020 | 6 | 2020 |
Comprehensive assessment of NR ligand polypharmacology by a multiplex reporter NR assay A Medvedev, M Moeser, L Medvedeva, E Martsen, A Granick, L Raines, ... Scientific Reports 12 (1), 3115, 2022 | 3 | 2022 |
Ex vivo immunological evaluation of stable mixed chimeric patients after matched related donor allogeneic transplantation in sickle cell disease LN Raines, MM Hsieh, T Nassehi, CM Drysdale, JF Tisdale, N Uchida Cytotherapy 21 (12), 1206-1215, 2019 | 3 | 2019 |
A serum-free method for efficient genetic modification and high-level hemoglobin production in human CD34+ cell-derived erythroid cells N Uchida, J Haro-Mora, A Fujita, L Raines, A Shvygin, L Skala, M Hsieh, ... MOLECULAR THERAPY 25 (5), 307-307, 2017 | 2 | 2017 |
How the unfolded protein response is a boon for tumors and a bane for the immune System LN Raines, SCC Huang ImmunoHorizons 7 (4), 256-264, 2023 | 1 | 2023 |
Intrabone Delivery of CD34+ Cells Using an Optimized Delivery System Does Not Enhance Engraftment in a Rhesus Macaque Model of Hematopoietic Stem Cell Transplantation K Stringaris, RF Hoyt, J Davidson, J Pantin, JF Tisdale, N Uchida, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | | 2018 |
GMP-Compliant Non-Viral CRISPR-Mediated Process Correcting the Sickle Cell Disease (SCD) Mutation in SCD Patient Cd34 (+) Cells Achieves 60% Wild Type Adult Hemoglobin … L Li, N Uchida, JH Mora, S Demirci, L Raines, C Allen, SS De Ravin, ... MOLECULAR THERAPY 26 (5), 371-372, 2018 | | 2018 |
Busulfan Combined with Immunosuppression Allows Efficient Engraftment of Gene-Modified Cells in a Rhesus Macaque Model N Uchida, L Raines, L Breden, A Ingersoll, AC Bonifacino, AE Krouse, ... MOLECULAR THERAPY 26 (5), 101-102, 2018 | | 2018 |
Development of an Evaluation System for Immunological Tolerance In Sickle Cell Disease HSC Transplanted Patients with Stable Mixed Chimerism LN Raines, MM Hsieh, JF Tisdale, N Uchida | | 2018 |