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Philip Beachy
Philip Beachy
Professor of Urology, Developmental Biology, Stanford University
Verified email at stanford.edu
Title
Cited by
Cited by
Year
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
C Chiang, Y Litingtung, E Lee, KE Young, JL Corden, H Westphal, ...
Nature 383 (6599), 407, 1996
35851996
The Hedgehog and Wnt signalling pathways in cancer
J Taipale, PA Beachy
nature 411 (6835), 349-354, 2001
18502001
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
JK Chen, J Taipale, MK Cooper, PA Beachy
Genes & development 16 (21), 2743-2748, 2002
16882002
Cholesterol modification of hedgehog signaling proteins in animal development
JA Porter, KE Young, PA Beachy
Science 274 (5285), 255-259, 1996
16051996
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
DM Berman, SS Karhadkar, A Maitra, R Montes de Oca, MR Gerstenblith, ...
Nature 425 (6960), 846-851, 2003
15872003
Tissue repair and stem cell renewal in carcinogenesis
PA Beachy, SS Karhadkar, DM Berman
Nature 432 (7015), 324-331, 2004
15342004
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
J Taipale, JK Chen, MK Cooper, B Wang, RK Mann, L Milenkovic, ...
Nature 406 (6799), 1005-1009, 2000
15342000
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
DN Watkins, DM Berman, SG Burkholder, B Wang, PA Beachy, SB Baylin
Nature 422 (6929), 313-317, 2003
13552003
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
SS Karhadkar, G Steven Bova, N Abdallah, S Dhara, D Gardner, A Maitra, ...
Nature 431 (7009), 707-712, 2004
13232004
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
B Wang, JF Fallon, PA Beachy
Cell 100 (4), 423-434, 2000
11412000
Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis
H Roelink, JA Porter, C Chiang, Y Tanabe, DT Chang, PA Beachy, ...
Cell 81 (3), 445-455, 1995
11041995
Small molecule modulation of Smoothened activity
JK Chen, J Taipale, KE Young, T Maiti, PA Beachy
Proceedings of the National Academy of Sciences 99 (22), 14071-14076, 2002
10932002
Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
C Zhao, A Chen, CH Jamieson, M Fereshteh, A Abrahamsson, J Blum, ...
Nature 458 (7239), 776-779, 2009
10882009
Teratogen-mediated inhibition of target tissue response to Shh signaling
MK Cooper, JA Porter, KE Young, PA Beachy
Science 280 (5369), 1603-1607, 1998
10421998
Medulloblastoma growth inhibition by hedgehog pathway blockade
DM Berman, SS Karhadkar, AR Hallahan, JI Pritchard, CG Eberhart, ...
Science 297 (5586), 1559-1561, 2002
10102002
The Hedgehog response network: sensors, switches, and routers
L Lum, PA Beachy
science 304 (5678), 1755-1759, 2004
9822004
Patched acts catalytically to suppress the activity of Smoothened
J Taipale, MK Cooper, T Maiti, PA Beachy
Nature 418 (6900), 892-896, 2002
9782002
Molecular genetics of the bithorax complex in Drosophila melanogaster
W Bender, M Akam, F Karch, PA Beachy, M Peifer, P Spierer, EB Lewis, ...
Science 221 (4605), 23-29, 1983
7431983
Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
JJ Lee, DP von Kessler, S Parks, PA Beachy
Cell 71 (1), 33-50, 1992
7231992
Autoproteolysis in hedgehog Protein Biogenesis
JJ Lee, SC Ekker, DP Von Kessler, JA Porter, BI Sun, PA Beachy
Science 266 (5190), 1528-1537, 1994
6831994
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