|NLRP6 protects Il10−/− mice from colitis by limiting colonization of Akkermansia muciniphila|
SS Seregin, N Golovchenko, B Schaf, J Chen, NA Pudlo, J Mitchell, ...
Cell reports 19 (4), 733-745, 2017
|The NLRP6 inflammasome recognizes lipoteichoic acid and regulates gram-positive pathogen infection|
H Hara, SS Seregin, D Yang, K Fukase, M Chamaillard, ES Alnemri, ...
Cell 175 (6), 1651-1664. e14, 2018
|Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic …|
I Evnouchidou, RP Kamal, SS Seregin, Y Goto, M Tsujimoto, A Hattori, ...
The Journal of Immunology 186 (4), 1909-1913, 2011
|Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses|
E Zervoudi, E Saridakis, JR Birtley, SS Seregin, E Reeves, P Kokkala, ...
Proceedings of the National Academy of Sciences 110 (49), 19890-19895, 2013
|Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy|
SS Seregin, DM Appledorn, AJ McBride, NJ Schuldt, YA Aldhamen, ...
Molecular Therapy 17 (4), 685-696, 2009
|Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors|
SS Seregin, A Amalfitano
Expert opinion on biological therapy 9 (12), 1521-1531, 2009
|A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing|
I Evnouchidou, J Birtley, S Seregin, A Papakyriakou, E Zervoudi, ...
The Journal of Immunology 189 (5), 2383-2392, 2012
|Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors|
DM Appledorn, A McBride, S Seregin, JM Scott, N Schuldt, A Kiang, ...
Gene therapy 15 (24), 1606-1617, 2008
|Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens|
SS Seregin, DPW Rastall, I Evnouchidou, CF Aylsworth, D Quiroga, ...
Autoimmunity 46 (8), 497-508, 2013
|NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury|
SS Seregin, N Golovchenko, B Schaf, J Chen, KA Eaton, GY Chen
Mucosal immunology 10 (2), 434-445, 2017
|Wild-type adenoviruses from groups A–F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent|
DM Appledorn, A Kiang, A McBride, H Jiang, S Seregin, JM Scott, ...
Gene therapy 15 (12), 885-901, 2008
|Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and …|
DM Appledorn, YA Aldhamen, S Godbehere, SS Seregin, A Amalfitano
Clinical and Vaccine Immunology 18 (1), 150-160, 2011
|ELOVL4-mediated production of very long-chain ceramides stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability|
NM Kady, X Liu, TA Lydic, MH Syed, S Navitskaya, Q Wang, SS Hammer, ...
Diabetes 67 (4), 769-781, 2018
|Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells|
YA Aldhamen, Y Pepelyayeva, DPW Rastall, SS Seregin, E Zervoudi, ...
Journal of innate immunity 7 (3), 275-289, 2015
|Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector–triggered immune responses in vitro and in vivo|
SS Seregin, YA Aldhamen, DM Appledorn, ZC Hartman, NJ Schuldt, ...
Blood, The Journal of the American Society of Hematology 116 (10), 1669-1677, 2010
|Improving adenovirus based gene transfer: strategies to accomplish immune evasion|
SS Seregin, A Amalfitano
Viruses 2 (9), 2013-2036, 2010
|Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens|
YA Aldhamen, DM Appledorn, SS Seregin, CJ Liu, NJ Schuldt, ...
The Journal of Immunology 186 (2), 722-732, 2011
|A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target|
DM Appledorn, YA Aldhamen, W DePas, SS Seregin, CJJ Liu, N Schuldt, ...
PLoS One 5 (3), e9579, 2010
|Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition|
T Toubai, H Fujiwara, C Rossi, M Riwes, H Tamaki, C Zajac, C Liu, ...
Nature microbiology 4 (5), 800-812, 2019
|Nod1 limits colitis-associated tumorigenesis by regulating IFN-γ production|
Y Zhan, SS Seregin, J Chen, GY Chen
The Journal of Immunology 196 (12), 5121-5129, 2016