Sergey Seregin
Sergey Seregin
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NLRP6 protects Il10−/− mice from colitis by limiting colonization of Akkermansia muciniphila
SS Seregin, N Golovchenko, B Schaf, J Chen, NA Pudlo, J Mitchell, ...
Cell reports 19 (4), 733-745, 2017
The NLRP6 inflammasome recognizes lipoteichoic acid and regulates gram-positive pathogen infection
H Hara, SS Seregin, D Yang, K Fukase, M Chamaillard, ES Alnemri, ...
Cell 175 (6), 1651-1664. e14, 2018
Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic …
I Evnouchidou, RP Kamal, SS Seregin, Y Goto, M Tsujimoto, A Hattori, ...
The Journal of Immunology 186 (4), 1909-1913, 2011
Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses
E Zervoudi, E Saridakis, JR Birtley, SS Seregin, E Reeves, P Kokkala, ...
Proceedings of the National Academy of Sciences 110 (49), 19890-19895, 2013
Transient pretreatment with glucocorticoid ablates innate toxicity of systemically delivered adenoviral vectors without reducing efficacy
SS Seregin, DM Appledorn, AJ McBride, NJ Schuldt, YA Aldhamen, ...
Molecular Therapy 17 (4), 685-696, 2009
Overcoming pre-existing adenovirus immunity by genetic engineering of adenovirus-based vectors
SS Seregin, A Amalfitano
Expert opinion on biological therapy 9 (12), 1521-1531, 2009
A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing
I Evnouchidou, J Birtley, S Seregin, A Papakyriakou, E Zervoudi, ...
The Journal of Immunology 189 (5), 2383-2392, 2012
Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors
DM Appledorn, A McBride, S Seregin, JM Scott, N Schuldt, A Kiang, ...
Gene therapy 15 (24), 1606-1617, 2008
Endoplasmic reticulum aminopeptidase-1 alleles associated with increased risk of ankylosing spondylitis reduce HLA-B27 mediated presentation of multiple antigens
SS Seregin, DPW Rastall, I Evnouchidou, CF Aylsworth, D Quiroga, ...
Autoimmunity 46 (8), 497-508, 2013
NLRP6 function in inflammatory monocytes reduces susceptibility to chemically induced intestinal injury
SS Seregin, N Golovchenko, B Schaf, J Chen, KA Eaton, GY Chen
Mucosal immunology 10 (2), 434-445, 2017
Wild-type adenoviruses from groups A–F evoke unique innate immune responses, of which HAd3 and SAd23 are partially complement dependent
DM Appledorn, A Kiang, A McBride, H Jiang, S Seregin, JM Scott, ...
Gene therapy 15 (12), 885-901, 2008
Sublingual administration of an adenovirus serotype 5 (Ad5)-based vaccine confirms Toll-like receptor agonist activity in the oral cavity and elicits improved mucosal and …
DM Appledorn, YA Aldhamen, S Godbehere, SS Seregin, A Amalfitano
Clinical and Vaccine Immunology 18 (1), 150-160, 2011
ELOVL4-mediated production of very long-chain ceramides stabilizes tight junctions and prevents diabetes-induced retinal vascular permeability
NM Kady, X Liu, TA Lydic, MH Syed, S Navitskaya, Q Wang, SS Hammer, ...
Diabetes 67 (4), 769-781, 2018
Autoimmune disease-associated variants of extracellular endoplasmic reticulum aminopeptidase 1 induce altered innate immune responses by human immune cells
YA Aldhamen, Y Pepelyayeva, DPW Rastall, SS Seregin, E Zervoudi, ...
Journal of innate immunity 7 (3), 275-289, 2015
Adenovirus capsid-display of the retro-oriented human complement inhibitor DAF reduces Ad vector–triggered immune responses in vitro and in vivo
SS Seregin, YA Aldhamen, DM Appledorn, ZC Hartman, NJ Schuldt, ...
Blood, The Journal of the American Society of Hematology 116 (10), 1669-1677, 2010
Improving adenovirus based gene transfer: strategies to accomplish immune evasion
SS Seregin, A Amalfitano
Viruses 2 (9), 2013-2036, 2010
Expression of the SLAM family of receptors adapter EAT-2 as a novel strategy for enhancing beneficial immune responses to vaccine antigens
YA Aldhamen, DM Appledorn, SS Seregin, CJ Liu, NJ Schuldt, ...
The Journal of Immunology 186 (2), 722-732, 2011
A New Adenovirus Based Vaccine Vector Expressing an Eimeria tenella Derived TLR Agonist Improves Cellular Immune Responses to an Antigenic Target
DM Appledorn, YA Aldhamen, W DePas, SS Seregin, CJJ Liu, N Schuldt, ...
PLoS One 5 (3), e9579, 2010
Host NLRP6 exacerbates graft-versus-host disease independent of gut microbial composition
T Toubai, H Fujiwara, C Rossi, M Riwes, H Tamaki, C Zajac, C Liu, ...
Nature microbiology 4 (5), 800-812, 2019
Nod1 limits colitis-associated tumorigenesis by regulating IFN-γ production
Y Zhan, SS Seregin, J Chen, GY Chen
The Journal of Immunology 196 (12), 5121-5129, 2016
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