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Alex Lam C Tsoi
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ...
Nature genetics 44 (12), 1341-1348, 2012
9492012
Transcriptome analysis of psoriasis in a large case–control sample: RNA-seq provides insights into disease mechanisms
B Li, LC Tsoi, WR Swindell, JE Gudjonsson, T Tejasvi, A Johnston, J Ding, ...
Journal of Investigative Dermatology 134 (7), 1828-1838, 2014
3272014
Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture
PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das, HM Kang, E Ellinghaus, ...
The American Journal of Human Genetics 97 (6), 816-836, 2015
2822015
Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants
LC Tsoi, PE Stuart, C Tian, JE Gudjonsson, S Das, M Zawistowski, ...
Nature communications 8 (1), 15382, 2017
2402017
Atopic dermatitis is an IL-13–dominant disease with greater molecular heterogeneity compared to psoriasis
LC Tsoi, E Rodriguez, F Degenhardt, H Baurecht, U Wehkamp, N Volks, ...
Journal of Investigative Dermatology 139 (7), 1480-1489, 2019
2342019
Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes
Y Okada, B Han, LC Tsoi, PE Stuart, E Ellinghaus, T Tejasvi, V Chandran, ...
The American Journal of Human Genetics 95 (2), 162-172, 2014
2082014
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin
LC Tsoi, MK Iyer, PE Stuart, WR Swindell, JE Gudjonsson, T Tejasvi, ...
Genome biology 16 (1), 1-15, 2015
2052015
Psoriasis: a mixed autoimmune and autoinflammatory disease
Y Liang, MK Sarkar, LC Tsoi, JE Gudjonsson
Current opinion in immunology 49, 1-8, 2017
2022017
Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci
LC Tsoi, SL Spain, E Ellinghaus, PE Stuart, F Capon, J Knight, T Tejasvi, ...
Nature communications 6 (1), 7001, 2015
1832015
High-density genotyping study identifies four new susceptibility loci for atopic dermatitis
D Ellinghaus, H Baurecht, J Esparza-Gordillo, E Rodríguez, A Matanovic, ...
Nature genetics 45 (7), 808-812, 2013
1762013
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre, M Knapp, ...
Nature genetics 47 (9), 1085-1090, 2015
1732015
Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms
H Baurecht, M Hotze, S Brand, C Büning, P Cormican, A Corvin, ...
The American Journal of Human Genetics 96 (1), 104-120, 2015
1612015
Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data
DS Tylee, J Sun, JL Hess, MA Tahir, E Sharma, R Malik, BB Worrall, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 177 …, 2018
1542018
Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa
MK Sarkar, GA Hile, LC Tsoi, X Xing, J Liu, Y Liang, CC Berthier, ...
Annals of the rheumatic diseases 77 (11), 1653-1664, 2018
1462018
Investigating the causal relationship of C-reactive protein with 32 complex somatic and psychiatric outcomes: a large-scale cross-consortium Mendelian randomization study
BP Prins, A Abbasi, A Wong, A Vaez, I Nolte, N Franceschini, PE Stuart, ...
PLoS medicine 13 (6), e1001976, 2016
1442016
Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL
E Ellinghaus, PE Stuart, D Ellinghaus, RP Nair, S Debrus, JV Raelson, ...
Journal of Investigative Dermatology 132 (4), 1133-1140, 2012
1392012
Assessing mitochondrial DNA variation and copy number in lymphocytes of~ 2,000 Sardinians using tailored sequencing analysis tools
J Ding, C Sidore, TJ Butler, MK Wing, Y Qian, O Meirelles, F Busonero, ...
PLoS genetics 11 (7), e1005306, 2015
1302015
Identification of functional and expression polymorphisms associated with risk for antineutrophil cytoplasmic autoantibody–associated vasculitis
PA Merkel, G Xie, PA Monach, X Ji, DJ Ciavatta, J Byun, BD Pinder, ...
Arthritis & rheumatology 69 (5), 1054-1066, 2017
1262017
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study
A Budu-Aggrey, B Brumpton, J Tyrrell, S Watkins, EH Modalsli, ...
PLoS medicine 16 (1), e1002739, 2019
1222019
Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
WR Swindell, KA Michaels, AJ Sutter, D Diaconu, Y Fritz, X Xing, ...
Genome medicine 9, 1-21, 2017
1172017
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