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Jai Shankar Yadlapalli, M.S.,Ph.D.
Jai Shankar Yadlapalli, M.S.,Ph.D.
Senior Manager, CMC Analytical @ Syndax
No verified email
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Cited by
Cited by
Year
Synthesis and evaluation of a series of benzothiophene acrylonitrile analogs as anticancer agents
NR Penthala, VN Sonar, J Horn, M Leggas, JSKB Yadlapalli, PA Crooks
MedChemComm 4 (7), 1073-1078, 2013
612013
Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu-and delta-opioid receptors
JSK Yadlapalli, BM Ford, A Ketkar, A Wan, NR Penthala, RL Eoff, ...
Pharmacological research 113, 335-347, 2016
262016
Evaluation of Analgesia, Tolerance, and the Mechanism of Action of Morphine-6-O-Sulfate Across Multiple Pain Modalities in Sprague-Dawley Rats
JSK Yadlapalli, N Dogra, AW Walbaum, WD Wessinger, PL Prather, ...
Anaesthesia and analgesia, 2017
172017
Degenerative Tissue Responses to Space-like Radiation Doses in a Rodent Model of Simulated Microgravity
P Chowdhury, N Akel, AJ Parsian, D Gaddy, RJ Griffin, JSK Yadlapalli, ...
Annals of Clinical and Laboratory Science 46 (2), 190-197, 2016
162016
A Novel and Efficient Tributyltin Azide-Mediated Synthesis of 1H-Tetrazolylstilbenes from Cyanostilbenes.
NR Penthala, S Bommagani, J Yadlapalli, PA Crooks
Tetrahedron Letters 57 (16), 1807-1810, 2016
112016
Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy
JSK Yadlapalli, N Dogra, AW Walbaum, PL Prather, PA Crooks, ...
Life Sciences 192 (https://doi.org/10.1016/j.lfs.2017.11.04), 151-159, 2018
82018
Evaluation of morphine-like effects of the mixed mu/delta agonist morphine-6-O sulfate in rats : Drug discrimination and physical dependence
JS Yadlapalli, SB Bommagani, RD Mahelona, A Wan, B Gannon, ...
Pharmacology research and perspectives 10, 2018
52018
Stability studies of potent opioid analgesic, morphine-6-O-sulfate in various buffers and biological matrices by HPLC-DAD analysis
Yadlapalli, Jai Shankar K.,Albayati, Zaineb A.F.,Penthala,Narasimha R ...
Biomedical chromatography, 2017
5*2017
Seeking Predictable Subject Characteristics That Influence Clinical Trial Discontinuation
JSKB Yadlapalli, IG Martin
Drug Information Journal 46 (3), 313-319, 2012
52012
Pinprick hypo-and hyperalgesia in diabetic rats: Can diet content affect experimental outcome?
JSK Yadlapalli, N Dogra, AW Walbaum, PL Prather, PA Crooks, ...
Neuroscience letters 673, 24-27, 2018
32018
Morphine 6-O-Sulfate Sodium: A Novel Opioid Therapeutic Alternative Evaluated in a Rat Model of Diabetic Neuropathy, It’s Pharmacological Characterization and Blood Brain …
JS Yadlapalli, N Dogra, B Ford, A Wan, P Prather, M Dobretsov, P Crooks
American Association of Pharmaceutical Scientists 2014, 2014
32014
(434) Analgesic profile of morphine 6-O-sulfate sodium: a mixed mu/delta agonist in the treatment of diabetic neuropathic pain
J Yadlapalli, N Dogra, B Ford, Z Albayati, N Penthala, P Prather, ...
The Journal of Pain 16 (4), S84, 2015
22015
A Pharmacokinetic study of morphine-6-O-sulfate in rat plasma and brain
JSK Yadlapalli, Z Albayati, P Breen, M Dobretsov, N Penthala, ...
Drug development research, 1-13, 2021
12021
Crystal structures of (Z)-5-[2-(benzo[b]thio­phen-2-yl)-1-(3,5-di­meth­­oxy­phen­yl)ethen­yl]-1H-tetra­zole and (Z)-5-[2-(benzo[b]thio­phen-3-yl)-1-(3,4,5-tri­meth­­oxy­phen­yl)ethen­yl]-1H …
N Penthala, JKB Yadlapalli, S Parkin, P Crooks
Acta Crystallographica Section E 72 (5), 652-655, 2016
12016
Morphine 6-O-Sulfate Sodium: A Novel Opiod Analgesic Alternative Evaluated in a Rat Model of Diabetic Neuropathy
MD Navdeep Dogra, JK Yadlapalli, M Dobretsov, PA Crooks
Anesthesia and Analgesia 118 (5S-Supplemental), S-214, 2014
12014
X-irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold
P Chowdhury, N Akel, AJ Parsian, R Griffin, ...
The FASEB Journal 30 (1), 762.1, 2016
2016
X-irradiation and Simulated Microgravity affects Rat Weight, Food Intake, Insulin and Paw Pressure Pain Threshold
P Chowdhury, N Akel, A Jamshidi-Parsian, RJ Griffin, J Yadlapalli, ...
Experimental biology 2016 ; Poster B499, 2016
2016
Preclinical evaluation of the 6-O-sulfate ester of morphine for the treatment of multimodal acute and chronic pain
JSK Yadlapalli
DAI-B 77/01(E), Jul 2016, 2015
2015
Novel &[alpha]9&[alpha]10 Nicotinic Acetylcholine Receptor Antagonist ZZ204G as Pain Management in Normal and Diabetic Rats
A Wan, JS Yadlapalli, E Fifer, M Dobretsov, P Crooks
Poster presentation at the 2015 AAPS Annual Meeting and Exposition; Orlando …, 2015
2015
Pharmacology, Pharmacokinetics and Side Effect Profile of Morphine-6-O-Sulfate and Therapeutic Implications in Diabetic Neuropathy
JS Yadlapalli, Z Albayati, B Ford, A Wan, NR Penthala, P Prather, ...
Poster presentation at the 2015 AAPS Annual Meeting and Exposition; Orlando …, 2015
2015
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