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Emzo de los Santos
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antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification
K Blin, T Wolf, MG Chevrette, X Lu, CJ Schwalen, SA Kautsar, ...
Nucleic acids research 45 (W1), W36-W41, 2017
12752017
A computational framework to explore large-scale biosynthetic diversity
JC Navarro-Muņoz, N Selem-Mojica, MW Mullowney, SA Kautsar, ...
Nature chemical biology 16 (1), 60-68, 2020
6362020
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
K Blin, V Pascal Andreu, ELC de los Santos, F Del Carratore, SY Lee, ...
Nucleic acids research 47 (D1), D625-D630, 2019
1842019
Engineering Transcriptional Regulator Effector Specificity Using Computational Design and In Vitro Rapid Prototyping: Developing a Vanillin Sensor
ELC de los Santos, JT Meyerowitz, SL Mayo, RM Murray
ACS synthetic biology 5 (4), 287-295, 2016
1052016
Design and implementation of a biomolecular concentration tracker
V Hsiao, ELC De Los Santos, WR Whitaker, JE Dueber, RM Murray
ACS synthetic biology 4 (2), 150-161, 2015
992015
Rieske non-heme iron-dependent oxygenases catalyse diverse reactions in natural product biosynthesis
C Perry, ELC De los Santos, LM Alkhalaf, GL Challis
Natural product reports 35 (7), 622-632, 2018
812018
NeuRiPP: Neural network identification of RiPP precursor peptides
ELC de los Santos
Scientific Reports 9, 2019
662019
Thioester reduction and aldehyde transamination are universal steps in actinobacterial polyketide alkaloid biosynthesis
ELC áde los Santos
Chemical science 8 (1), 411-415, 2017
542017
Structural basis for chain release from the enacyloxin polyketide synthase
S Kosol, A Gallo, D Griffiths, TR Valentic, J Masschelein, M Jenner, ...
Nature chemistry 11 (10), 913-923, 2019
502019
Mechanistic insights into class B radical-S-adenosylmethionine methylases: ubiquitous tailoring enzymes in natural product biosynthesis
S Zhou, LM Alkhalaf, EL de Los Santos, GL Challis
Current opinion in chemical biology 35, 73-79, 2016
382016
Pentamycin Biosynthesis in Philippine Streptomyces sp. S816: Cytochrome P450-Catalyzed Installation of the C-14 Hydroxyl Group
S Zhou, L Song, J Masschelein, FAM Sumang, IA Papa, TO Zulaybar, ...
ACS Chemical Biology 14 (6), 1305-1309, 2019
242019
Reprogramming nonribosomal peptide synthesis by surgical mutation
DL Niquille, DA Hansen, D Hilvert
Synlett 30 (19), 2123-2130, 2019
92019
clusterTools: proximity searches for functional elements to identify putative biosynthetic gene clusters
ELC de los Santos, GL Challis
BioRxiv, 119214, 2017
72017
Design and implementation of a biomolecular circuit for tracking protein concentration
ELC de los Santos, V Hsiao, RM Murray
2013 American Control Conference, 2290-2294, 2013
52013
clusterTools: functional element identification for the in silico prioritization of biosynthetic gene clusters
E Lorenzo de los Santos, G Challis
Access Microbiology 1 (1A), 301, 2019
32019
Design and implementation of a synthetic biomolecular concentration tracker
V Hsiao, ELC de los Santos, WR Whitaker, JE Dueber, RM Murray
bioRxiv, 000448, 2013
22013
Genome library mining with BiG-SCAPE/CORASON reveals novel detoxin natural products
MW Mullowney, JC Navarro-Muņoz, N Selem-Mojica, LTD Cappelini, ...
SIMB Annual Meeting 2018, 2018
2018
Expanding the Toolkit for Synthetic Biology: Frameworks for Native-like Non-natural Gene Circuits
ELC De los Santos
California Institute of Technology, 2015
2015
clear all; clc; close all; tic% Uncomment lines to run simulations for different figures% Be sure to re-comment out other figures% By default Figure 2 is uncommented to start
FV Hsiao, ELC de los Santos, WR Whitaker, JE Dueber, RM Murray
2013
Integrated structural biology of enacyloxin polyketide synthase
S Kosol, A Gallo, D Griffiths, TR Valentic, JL Masschelein, M Jenner, ...
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