| Aβ42‐driven cerebral amyloidosis in transgenic mice reveals early and robust pathology R Radde, T Bolmont, SA Kaeser, J Coomaraswamy, D Lindau, L Stoltze, ... EMBO reports 7 (9), 940-946, 2006 | 1081 | 2006 |
| Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice V Rhein, X Song, A Wiesner, LM Ittner, G Baysang, F Meier, L Ozmen, ... Proceedings of the National Academy of Sciences 106 (47), 20057-20062, 2009 | 746 | 2009 |
| Targeting huntingtin expression in patients with Huntington’s disease SJ Tabrizi, BR Leavitt, GB Landwehrmeyer, EJ Wild, C Saft, RA Barker, ... New England Journal of Medicine 380 (24), 2307-2316, 2019 | 631 | 2019 |
| Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice O Wirths, G Multhaup, C Czech, V Blanchard, S Moussaoui, G Tremp, ... Neuroscience letters 306 (1-2), 116-120, 2001 | 420 | 2001 |
| Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease C Schmitz, BPF Rutten, A Pielen, S Schäfer, O Wirths, G Tremp, C Czech, ... The American journal of pathology 164 (4), 1495-1502, 2004 | 376 | 2004 |
| The Parkinson's progression markers initiative (PPMI)–establishing a PD biomarker cohort K Marek, S Chowdhury, A Siderowf, S Lasch, CS Coffey, ... Annals of clinical and translational neurology 5 (12), 1460-1477, 2018 | 371 | 2018 |
| Amyloid β-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis U Keil, A Bonert, CA Marques, I Scherping, J Weyermann, ... Journal of Biological Chemistry 279 (48), 50310-50320, 2004 | 369 | 2004 |
| Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice V Blanchard, S Moussaoui, C Czech, N Touchet, B Bonici, M Planche, ... Experimental neurology 184 (1), 247-263, 2003 | 352 | 2003 |
| Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and β-amyloid precursor protein A Weidemann, K Paliga, U Dürrwang, C Czech, G Evin, CL Masters, ... Nature medicine 3 (3), 328-332, 1997 | 289 | 1997 |
| Identification and differential expression of a novel alternative splice isoform of the beta A4 amyloid precursor protein (APP) mRNA in leukocytes and brain microglial cells. G König, U Mönning, C Czech, R Prior, R Banati, U Schreiter-Gasser, ... Journal of Biological Chemistry 267 (15), 10804-10809, 1992 | 284 | 1992 |
| Key factors in Alzheimer's disease: β‐amyloid precursor protein processing, metabolism and intraneuronal transport TA Bayer, O Wirths, K Majtényi, T Hartmann, G Multhaup, K Beyreuther, ... Brain Pathology 11 (1), 1-11, 2001 | 257 | 2001 |
| Evaluation of smartphone‐based testing to generate exploratory outcome measures in a phase 1 Parkinson's disease clinical trial F Lipsmeier, KI Taylor, T Kilchenmann, D Wolf, A Scotland, ... Movement Disorders 33 (8), 1287-1297, 2018 | 240 | 2018 |
| Presenilins and Alzheimer’s disease: biological functions and pathogenic mechanisms C Czech, G Tremp, L Pradier Progress in neurobiology 60 (4), 363-384, 2000 | 218 | 2000 |
| Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype A Fossgreen, B Brückner, C Czech, CL Masters, K Beyreuther, R Paro Proceedings of the National Academy of Sciences 95 (23), 13703-13708, 1998 | 215 | 1998 |
| PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation JG Richards, GA Higgins, AM Ouagazzal, L Ozmen, JNC Kew, ... Journal of Neuroscience 23 (26), 8989-9003, 2003 | 212 | 2003 |
| The beta‐amyloid domain is essential for axonal sorting of amyloid precursor protein. PJ Tienari, B De Strooper, E Ikonen, M Simons, A Weidemann, C Czech, ... The EMBO journal 15 (19), 5218-5229, 1996 | 187 | 1996 |
| Metabolite profiling of Alzheimer's disease cerebrospinal fluid C Czech, P Berndt, K Busch, O Schmitz, J Wiemer, V Most, H Hampel, ... PloS one 7 (2), e31501, 2012 | 179 | 2012 |
| Early and rapid de novo synthesis of Alzheimer βA4‐amyloid precursor protein (APP) in activated microglia RB Banati, J Gehrmann, C Czech, U Mönning, LL Jones, G König, ... Glia 9 (3), 199-210, 1993 | 179 | 1993 |
| Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice K Schuessel, S Schäfer, TA Bayer, C Czech, L Pradier, F Müller-Spahn, ... Neurobiology of disease 18 (1), 89-99, 2005 | 171 | 2005 |
| Intraneuronal APP/Aβ Trafficking and Plaque Formation in β‐Amyloid Precursor Protein and Presenilin‐1 Transgenic Mice O Wirths, G Multhaup, C Czech, N Feldmann, V Blanchard, G Tremp, ... Brain Pathology 12 (3), 275-286, 2002 | 156 | 2002 |
Anne EckertProfessor Anne Eckert, PhD Head, Neurobiology Lab for Brain Aging and Mental Health Transfaculty Research Platform Molecular & Cognitive Neuroscience (MCN) University of BaselVerified email at upkbs.ch
