Christoph Welsch
Christoph Welsch
Goethe University Hospital-Frankfurt, Germany
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Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients
S Susser, C Welsch, Y Wang, M Zettler, FS Domingues, U Karey, ...
Hepatology 50 (6), 1709-1718, 2009
The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology
J Trebicka, J Fernandez, M Papp, P Caraceni, W Laleman, C Gambino, ...
Journal of hepatology 73 (4), 842-854, 2020
New direct-acting antiviral agents for the treatment of hepatitis C virus infection and perspectives
C Welsch, A Jesudian, S Zeuzem, I Jacobson
Gut 61 (Suppl 1), i36-i46, 2012
Pharmacokinetics of peginterferons
S Zeuzem, C Welsch, E Herrmann
Seminars in liver disease 23 (S 1), 023-028, 2003
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis
J Trebicka, J Fernandez, M Papp, P Caraceni, W Laleman, C Gambino, ...
Journal of hepatology 74 (5), 1097-1108, 2021
Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation
D Yamane, DR McGivern, E Wauthier, MK Yi, VJ Madden, C Welsch, ...
Nature medicine 20 (8), 927-935, 2014
Protease inhibitor–resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus
T Shimakami, C Welsch, D Yamane, DR McGivern, MK Yi, S Zeuzem, ...
Gastroenterology 140 (2), 667-675, 2011
Bacterial infection‐triggered acute‐on‐chronic liver failure is associated with increased mortality
MM Mücke, T Rumyantseva, VT Mücke, K Schwarzkopf, S Joshi, ...
Liver International 38 (4), 645-653, 2018
The efficacy and safety of direct acting antiviral treatment and clinical significance of drug–drug interactions in elderly patients with chronic hepatitis C virus infection
J Vermehren, KH Peiffer, C Welsch, G Grammatikos, MW Welker, N Weiler, ...
Alimentary pharmacology & therapeutics 44 (8), 856-865, 2016
Base pairing between hepatitis C virus RNA and microRNA 122 3′ of its seed sequence is essential for genome stabilization and production of infectious virus
T Shimakami, D Yamane, C Welsch, L Hensley, RK Jangra, SM Lemon
Journal of virology 86 (13), 7372-7383, 2012
Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus
C Welsch, FS Domingues, S Susser, I Antes, C Hartmann, G Mayr, ...
Genome biology 9, 1-18, 2008
Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair
G Plotz, C Welsch, L Giron-Monzon, P Friedhoff, M Albrecht, A Piiper, ...
Nucleic acids research 34 (22), 6574-6586, 2006
Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells
H Dansako, D Yamane, C Welsch, DR McGivern, F Hu, N Kato, ...
PLoS pathogens 9 (5), e1003345, 2013
Reduced dose and duration of peginterferon alfa-2b and weight-based ribavirin in patients with genotype 2 and 3 chronic hepatitis C
M Manns, S Zeuzem, A Sood, Y Lurie, M Cornberg, H Klinker, P Buggisch, ...
Journal of hepatology 55 (3), 554-563, 2011
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
S Monteiro, J Grandt, FE Uschner, N Kimer, JL Madsen, R Schierwagen, ...
Gut 70 (2), 379-387, 2021
Trends and the course of liver cirrhosis and its complications in Germany: Nationwide population-based study (2005 to 2018)
W Gu, H Hortlik, HP Erasmus, L Schaaf, Y Zeleke, FE Uschner, P Ferstl, ...
The Lancet Regional Health–Europe 12, 2022
Macrophage-derived extracellular vesicles induce long-lasting immunity against hepatitis C virus which is blunted by polyunsaturated fatty acids
C Cai, B Koch, K Morikawa, G Suda, N Sakamoto, S Rueschenbaum, ...
Frontiers in immunology 9, 723, 2018
Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III
S Kim, C Welsch, MK Yi, SM Lemon
Journal of virology 85 (13), 6645-6656, 2011
Ongoing liver inflammation in patients with chronic hepatitis C and sustained virological response
C Welsch, M Efinger, M von Wagner, E Herrmann, S Zeuzem, TM Welzel, ...
PLoS One 12 (2), e0171755, 2017
Amino acid variations in hepatitis C virus p7 and sensitivity to antiviral combination therapy with amantadine in chronic hepatitis C
U Mihm, N Grigorian, C Welsch, E Herrmann, B Kronenberger, G Teuber, ...
Antiviral therapy 11 (4), 507-519, 2006
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