The PREDICT study uncovers three clinical courses of acutely decompensated cirrhosis that have distinct pathophysiology J Trebicka, J Fernandez, M Papp, P Caraceni, W Laleman, C Gambino, ... Journal of hepatology 73 (4), 842-854, 2020 | 419 | 2020 |
Characterization of resistance to the protease inhibitor boceprevir in hepatitis C virus–infected patients S Susser, C Welsch, Y Wang, M Zettler, FS Domingues, U Karey, ... Hepatology 50 (6), 1709-1718, 2009 | 401 | 2009 |
New direct-acting antiviral agents for the treatment of hepatitis C virus infection and perspectives C Welsch, A Jesudian, S Zeuzem, I Jacobson Gut 61 (Suppl 1), i36-i46, 2012 | 243 | 2012 |
Pharmacokinetics of peginterferons S Zeuzem, C Welsch, E Herrmann Seminars in liver disease 23 (S 1), 023-028, 2003 | 243 | 2003 |
PREDICT identifies precipitating events associated with the clinical course of acutely decompensated cirrhosis J Trebicka, J Fernandez, M Papp, P Caraceni, W Laleman, C Gambino, ... Journal of hepatology 74 (5), 1097-1108, 2021 | 236 | 2021 |
Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation D Yamane, DR McGivern, E Wauthier, MK Yi, VJ Madden, C Welsch, ... Nature medicine 20 (8), 927-935, 2014 | 161 | 2014 |
Protease inhibitor–resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus T Shimakami, C Welsch, D Yamane, DR McGivern, MK Yi, S Zeuzem, ... Gastroenterology 140 (2), 667-675, 2011 | 150 | 2011 |
Bacterial infection‐triggered acute‐on‐chronic liver failure is associated with increased mortality MM Mücke, T Rumyantseva, VT Mücke, K Schwarzkopf, S Joshi, ... Liver International 38 (4), 645-653, 2018 | 137 | 2018 |
The efficacy and safety of direct acting antiviral treatment and clinical significance of drug–drug interactions in elderly patients with chronic hepatitis C virus infection J Vermehren, KH Peiffer, C Welsch, G Grammatikos, MW Welker, N Weiler, ... Alimentary pharmacology & therapeutics 44 (8), 856-865, 2016 | 109 | 2016 |
Base pairing between hepatitis C virus RNA and microRNA 122 3′ of its seed sequence is essential for genome stabilization and production of infectious virus T Shimakami, D Yamane, C Welsch, L Hensley, RK Jangra, SM Lemon Journal of virology 86 (13), 7372-7383, 2012 | 108 | 2012 |
Trends and the course of liver cirrhosis and its complications in Germany: Nationwide population-based study (2005 to 2018) W Gu, H Hortlik, HP Erasmus, L Schaaf, Y Zeleke, FE Uschner, P Ferstl, ... The Lancet Regional Health–Europe 12, 2022 | 105 | 2022 |
Molecular basis of telaprevir resistance due to V36 and T54 mutations in the NS3-4A protease of the hepatitis C virus C Welsch, FS Domingues, S Susser, I Antes, C Hartmann, G Mayr, ... Genome biology 9, 1-18, 2008 | 102 | 2008 |
Mutations in the MutSα interaction interface of MLH1 can abolish DNA mismatch repair G Plotz, C Welsch, L Giron-Monzon, P Friedhoff, M Albrecht, A Piiper, ... Nucleic acids research 34 (22), 6574-6586, 2006 | 90 | 2006 |
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation S Monteiro, J Grandt, FE Uschner, N Kimer, JL Madsen, R Schierwagen, ... Gut 70 (2), 379-387, 2021 | 86 | 2021 |
Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells H Dansako, D Yamane, C Welsch, DR McGivern, F Hu, N Kato, ... PLoS pathogens 9 (5), e1003345, 2013 | 83 | 2013 |
Reduced dose and duration of peginterferon alfa-2b and weight-based ribavirin in patients with genotype 2 and 3 chronic hepatitis C M Manns, S Zeuzem, A Sood, Y Lurie, M Cornberg, H Klinker, P Buggisch, ... Journal of hepatology 55 (3), 554-563, 2011 | 82 | 2011 |
Macrophage-derived extracellular vesicles induce long-lasting immunity against hepatitis C virus which is blunted by polyunsaturated fatty acids C Cai, B Koch, K Morikawa, G Suda, N Sakamoto, S Rueschenbaum, ... Frontiers in immunology 9, 723, 2018 | 79 | 2018 |
Regulation of the production of infectious genotype 1a hepatitis C virus by NS5A domain III S Kim, C Welsch, MK Yi, SM Lemon Journal of virology 85 (13), 6645-6656, 2011 | 68 | 2011 |
Ongoing liver inflammation in patients with chronic hepatitis C and sustained virological response C Welsch, M Efinger, M von Wagner, E Herrmann, S Zeuzem, TM Welzel, ... PloS one 12 (2), e0171755, 2017 | 64 | 2017 |
Cardiodynamic state is associated with systemic inflammation and fatal acute‐on‐chronic liver failure M Praktiknjo, S Monteiro, J Grandt, N Kimer, JL Madsen, MP Werge, ... Liver international 40 (6), 1457-1466, 2020 | 60 | 2020 |