A second transmissible cancer in Tasmanian devils RJ Pye, D Pemberton, C Tovar, JMC Tubio, KA Dun, S Fox, J Darby, ... Proceedings of the National Academy of Sciences 113 (2), 374-379, 2016 | 232 | 2016 |
Pro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis ZY Ong, RJ Gibson, JM Bowen, AM Stringer, JM Darby, RM Logan, ... Radiation oncology 5 (1), 1-8, 2010 | 171 | 2010 |
Genetic homogeneity of axenic isolates of Giardia intestinalis derived from acute and chronically infected individuals in Mexico R Cedillo-Rivera, JM Darby, JA Enciso-Moreno, G Ortega-Pierres, PL Ey Parasitology Research 90, 119-123, 2003 | 83 | 2003 |
Regression of devil facial tumour disease following immunotherapy in immunised Tasmanian devils C Tovar, RJ Pye, A Kreiss, Y Cheng, GK Brown, J Darby, RC Malley, ... Scientific reports 7 (1), 43827, 2017 | 79 | 2017 |
A simplified suite of methods to evaluate chelator conjugation of antibodies: effects on hydrodynamic radius and biodistribution F Al-Ejeh, JM Darby, B Thierry, MP Brown Nuclear medicine and biology 36 (4), 395-402, 2009 | 48 | 2009 |
The La autoantigen is a malignancy-associated cell death target that is induced by DNA-damaging drugs F Al-Ejeh, JM Darby, MP Brown Clinical Cancer Research 13 (18), 5509s-5518s, 2007 | 48 | 2007 |
In vivo targeting of dead tumor cells in a murine tumor model using a monoclonal antibody specific for the La autoantigen F Al-Ejeh, JM Darby, K Pensa, KR Diener, JD Hayball, MP Brown Clinical cancer research 13 (18), 5519s-5527s, 2007 | 47 | 2007 |
Giardia intestinalis: detection of major genotypes by restriction analysis of gene amplification products PL Ey, JM Darby, RH Andrews, G Mayrhofer International journal for parasitology 23 (5), 591-600, 1993 | 40 | 1993 |
APOMAB®, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy F Al-Ejeh, JM Darby, C Tsopelas, D Smyth, J Manavis, MP Brown PloS one 4 (2), e4558, 2009 | 38 | 2009 |
The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB® AH Staudacher, F Al-Ejeh, CK Fraser, JM Darby, DM Roder, ... EJNMMI research 4 (1), 1-13, 2014 | 35 | 2014 |
Chemotherapy synergizes with radioimmunotherapy targeting La autoantigen in tumors F Al-Ejeh, JM Darby, MP Brown PLoS One 4 (2), e4630, 2009 | 34 | 2009 |
Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii) AL Patchett, THH Coorens, J Darby, R Wilson, MJ McKay, KS Kamath, ... Cellular and Molecular Life Sciences 77, 1847-1858, 2020 | 33 | 2020 |
Mitogen‐activated Tasmanian devil blood mononuclear cells kill devil facial tumour disease cells GK Brown, C Tovar, AA Cooray, A Kreiss, J Darby, JM Murphy, ... Immunology and cell biology 94 (7), 673-679, 2016 | 27 | 2016 |
Absence of tumor necrosis factor supports alternative activation of macrophages in the liver after infection with Leishmania major S Hu, C Marshall, J Darby, W Wei, AB Lyons, H Körner Frontiers in Immunology 9, 1, 2018 | 25 | 2018 |
A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers AS Flies, JM Darby, PR Lennard, PR Murphy, CEB Ong, TL Pinfold, ... Science Advances 6 (27), eaba5031, 2020 | 18 | 2020 |
The immunomodulatory small molecule imiquimod induces apoptosis in devil facial tumour cell lines AL Patchett, JM Darby, C Tovar, AB Lyons, GM Woods PLoS One 11 (12), e0168068, 2016 | 17 | 2016 |
Postchemotherapy and tumor-selective targeting with the La-specific DAB4 monoclonal antibody relates to apoptotic cell clearance F Al-Ejeh, AH Staudacher, DR Smyth, JM Darby, D Denoyer, C Tsopelas, ... Journal of Nuclear Medicine 55 (5), 772-779, 2014 | 17 | 2014 |
NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers CEB Ong, AL Patchett, JM Darby, J Chen, GS Liu, AB Lyons, GM Woods, ... Journal of Cancer Research and Clinical Oncology 147, 1973-1991, 2021 | 15 | 2021 |
VSP417-6, a variant-specific surface protein encoded at a sixth locus within the vsp417 gene subfamily of Giardia intestinalis PL Ey, JM Darby International journal for parasitology 32 (4), 425-436, 2002 | 12 | 2002 |
Post-release immune responses of Tasmanian devils vaccinated with an experimental devil facial tumour disease vaccine R Pye, J Darby, AS Flies, S Fox, S Carver, J Elmer, K Swift, C Hogg, ... Wildlife Research 48 (8), 701-712, 2021 | 11 | 2021 |