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David A Mitchell
David A Mitchell
Gilbert Family Foundation
Verified email at gilbertfamilyfoundation.org - Homepage
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Cited by
Year
Thematic review series: lipid posttranslational modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases
DA Mitchell, A Vasudevan, ME Linder, RJ Deschenes
Journal of lipid research 47 (6), 1118-1127, 2006
5012006
Vectors for the inducible overexpression of glutathione S‐transferase fusion proteins in yeast
DA Mitchell, TK Marshall, RJ Deschenes
Yeast 9 (7), 715-722, 1993
3671993
Erf2, a Novel Gene Product That Affects the Localization and Palmitoylation of Ras2 in Saccharomyces cerevisiae
DJ Bartels, DA Mitchell, X Dong, RJ Deschenes
Molecular and cellular biology 19 (10), 6775-6787, 1999
2471999
Mutational Analysis of Saccharomyces cerevisiae Erf2 Reveals a Two-step Reaction Mechanism for Protein Palmitoylation by DHHC Enzymes*♦
DA Mitchell, G Mitchell, Y Ling, C Budde, RJ Deschenes
Journal of Biological Chemistry 285 (49), 38104-38114, 2010
1722010
Synthetic lethal analysis implicates Ste20p, a p21-activated protein kinase, in polarisome activation
AS Goehring, DA Mitchell, AHY Tong, ME Keniry, C Boone, ...
Molecular biology of the cell 14 (4), 1501-1516, 2003
1222003
Triiodothyronine stimulates transcription of the fatty acid synthase gene in chick embryo hepatocytes in culture. Insulin and insulin-like growth factor amplify that effect.
SR Stapleton, DA Mitchell, LM Salati, AG Goodridge
Journal of Biological Chemistry 265 (30), 18442-18446, 1990
1101990
Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae
X Dong, DA Mitchell, S Lobo, L Zhao, DJ Bartels, RJ Deschenes
Molecular and cellular biology, 2003
962003
Nutritional regulation and tissue-specific expression of the malic enzyme gene in the chicken. Transcriptional control and chromatin structure.
XJ Ma, LM Salati, SE Ash, DA Mitchell, SA Klautky, DA Fantozzi, ...
Journal of Biological Chemistry 265 (30), 18435-18441, 1990
851990
The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1
PK Bahia, TA Parks, KR Stanford, DA Mitchell, S Varma, SM Stevens Jr, ...
Journal of General Physiology 147 (6), 451-465, 2016
682016
Triiodothyronine-induced accumulations of malic enzyme, fatty acid synthase, acetyl-coenzyme A carboxylase, and their mRNAs are blocked by protein kinase inhibitors …
J Swierczynski, DA Mitchell, DS Reinhold, LM Salati, SR Stapleton, ...
Journal of Biological Chemistry 266 (26), 17459-17466, 1991
661991
The Phosphotyrosyl Phosphatase Activator, Ncs1p (Rrd1p), Functions with Cla4p To Regulate the G2/M Transition in Saccharomyces cerevisiae
DA Mitchell, GF Sprague Jr
Molecular and cellular biology 21 (2), 488-500, 2001
622001
Mutations in the X-linked intellectual disability gene, zDHHC9, alter autopalmitoylation activity by distinct mechanisms
DA Mitchell, LD Hamel, KD Reddy, L Farh, LM Rettew, PR Sanchez, ...
Journal of Biological Chemistry 289 (26), 18582-18592, 2014
612014
Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome
RS Beard Jr, X Yang, JE Meegan, JW Overstreet, CGY Yang, JA Elliott, ...
Nature communications 7 (1), 12823, 2016
602016
The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate
DA Mitchell, LD Hamel, K Ishizuka, G Mitchell, LM Schaefer, ...
Journal of Biological Chemistry 287 (41), 34337-34348, 2012
592012
Cytochrome b 5 is a major reductant in vivo of human indoleamine 2,3‐dioxygenase expressed in yeast
E Vottero, DA Mitchell, MJ Page, RTA MacGillivray, IJ Sadowski, ...
FEBS letters 580 (9), 2265-2268, 2006
472006
Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway
L Farh, DA Mitchell, RJ Deschenes
Archives of biochemistry and biophysics 318 (1), 113-121, 1995
401995
TFII-I and USF (RBF-2) regulate ras/MAPK-responsive HIV-1 transcription in t cells
I Sadowski, DA Mitchell
European Journal of Cancer 41 (16), 2528-2536, 2005
382005
A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening
LD Hamel, RJ Deschenes, DA Mitchell
Analytical biochemistry 460, 1-8, 2014
312014
Identification of protein palmitoylation inhibitors from a scaffold ranking library
L D Hamel, B J Lenhart, D A Mitchell, R G Santos, M A Giulianotti, ...
Combinatorial chemistry & high throughput screening 19 (4), 262-274, 2016
282016
Analysis of the diffusion of Ras2 in Saccharomyces cerevisiae using fluorescence recovery after photobleaching
KC Vinnakota, DA Mitchell, RJ Deschenes, T Wakatsuki, DA Beard
Physical biology 7 (2), 026011, 2010
232010
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