Thematic review series: lipid posttranslational modifications. Protein palmitoylation by a family of DHHC protein S-acyltransferases DA Mitchell, A Vasudevan, ME Linder, RJ Deschenes Journal of lipid research 47 (6), 1118-1127, 2006 | 501 | 2006 |
Vectors for the inducible overexpression of glutathione S‐transferase fusion proteins in yeast DA Mitchell, TK Marshall, RJ Deschenes Yeast 9 (7), 715-722, 1993 | 367 | 1993 |
Erf2, a Novel Gene Product That Affects the Localization and Palmitoylation of Ras2 in Saccharomyces cerevisiae DJ Bartels, DA Mitchell, X Dong, RJ Deschenes Molecular and cellular biology 19 (10), 6775-6787, 1999 | 247 | 1999 |
Mutational Analysis of Saccharomyces cerevisiae Erf2 Reveals a Two-step Reaction Mechanism for Protein Palmitoylation by DHHC Enzymes*♦ DA Mitchell, G Mitchell, Y Ling, C Budde, RJ Deschenes Journal of Biological Chemistry 285 (49), 38104-38114, 2010 | 172 | 2010 |
Synthetic lethal analysis implicates Ste20p, a p21-activated protein kinase, in polarisome activation AS Goehring, DA Mitchell, AHY Tong, ME Keniry, C Boone, ... Molecular biology of the cell 14 (4), 1501-1516, 2003 | 122 | 2003 |
Triiodothyronine stimulates transcription of the fatty acid synthase gene in chick embryo hepatocytes in culture. Insulin and insulin-like growth factor amplify that effect. SR Stapleton, DA Mitchell, LM Salati, AG Goodridge Journal of Biological Chemistry 265 (30), 18442-18446, 1990 | 110 | 1990 |
Palmitoylation and plasma membrane localization of Ras2p by a nonclassical trafficking pathway in Saccharomyces cerevisiae X Dong, DA Mitchell, S Lobo, L Zhao, DJ Bartels, RJ Deschenes Molecular and cellular biology, 2003 | 96 | 2003 |
Nutritional regulation and tissue-specific expression of the malic enzyme gene in the chicken. Transcriptional control and chromatin structure. XJ Ma, LM Salati, SE Ash, DA Mitchell, SA Klautky, DA Fantozzi, ... Journal of Biological Chemistry 265 (30), 18435-18441, 1990 | 85 | 1990 |
The exceptionally high reactivity of Cys 621 is critical for electrophilic activation of the sensory nerve ion channel TRPA1 PK Bahia, TA Parks, KR Stanford, DA Mitchell, S Varma, SM Stevens Jr, ... Journal of General Physiology 147 (6), 451-465, 2016 | 68 | 2016 |
Triiodothyronine-induced accumulations of malic enzyme, fatty acid synthase, acetyl-coenzyme A carboxylase, and their mRNAs are blocked by protein kinase inhibitors … J Swierczynski, DA Mitchell, DS Reinhold, LM Salati, SR Stapleton, ... Journal of Biological Chemistry 266 (26), 17459-17466, 1991 | 66 | 1991 |
The Phosphotyrosyl Phosphatase Activator, Ncs1p (Rrd1p), Functions with Cla4p To Regulate the G2/M Transition in Saccharomyces cerevisiae DA Mitchell, GF Sprague Jr Molecular and cellular biology 21 (2), 488-500, 2001 | 62 | 2001 |
Mutations in the X-linked intellectual disability gene, zDHHC9, alter autopalmitoylation activity by distinct mechanisms DA Mitchell, LD Hamel, KD Reddy, L Farh, LM Rettew, PR Sanchez, ... Journal of Biological Chemistry 289 (26), 18582-18592, 2014 | 61 | 2014 |
Palmitoyl acyltransferase DHHC21 mediates endothelial dysfunction in systemic inflammatory response syndrome RS Beard Jr, X Yang, JE Meegan, JW Overstreet, CGY Yang, JA Elliott, ... Nature communications 7 (1), 12823, 2016 | 60 | 2016 |
The Erf4 subunit of the yeast Ras palmitoyl acyltransferase is required for stability of the Acyl-Erf2 intermediate and palmitoyl transfer to a Ras2 substrate DA Mitchell, LD Hamel, K Ishizuka, G Mitchell, LM Schaefer, ... Journal of Biological Chemistry 287 (41), 34337-34348, 2012 | 59 | 2012 |
Cytochrome b 5 is a major reductant in vivo of human indoleamine 2,3‐dioxygenase expressed in yeast E Vottero, DA Mitchell, MJ Page, RTA MacGillivray, IJ Sadowski, ... FEBS letters 580 (9), 2265-2268, 2006 | 47 | 2006 |
Farnesylation and proteolysis are sequential, but distinct steps in the CaaX box modification pathway L Farh, DA Mitchell, RJ Deschenes Archives of biochemistry and biophysics 318 (1), 113-121, 1995 | 40 | 1995 |
TFII-I and USF (RBF-2) regulate ras/MAPK-responsive HIV-1 transcription in t cells I Sadowski, DA Mitchell European Journal of Cancer 41 (16), 2528-2536, 2005 | 38 | 2005 |
A fluorescence-based assay to monitor autopalmitoylation of zDHHC proteins applicable to high-throughput screening LD Hamel, RJ Deschenes, DA Mitchell Analytical biochemistry 460, 1-8, 2014 | 31 | 2014 |
Identification of protein palmitoylation inhibitors from a scaffold ranking library L D Hamel, B J Lenhart, D A Mitchell, R G Santos, M A Giulianotti, ... Combinatorial chemistry & high throughput screening 19 (4), 262-274, 2016 | 28 | 2016 |
Analysis of the diffusion of Ras2 in Saccharomyces cerevisiae using fluorescence recovery after photobleaching KC Vinnakota, DA Mitchell, RJ Deschenes, T Wakatsuki, DA Beard Physical biology 7 (2), 026011, 2010 | 23 | 2010 |