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Rachel Sammons
Rachel Sammons
Verified email at utexas.edu
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Year
JNK signaling in stem cell self-renewal and differentiation
T Semba, R Sammons, X Wang, X Xie, KN Dalby, NT Ueno
International journal of molecular sciences 21 (7), 2613, 2020
572020
Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer
M Gagliardi, MK Pitner, J Park, X Xie, H Saso, RA Larson, RM Sammons, ...
Scientific reports 10 (1), 8537, 2020
352020
Targeting ERK beyond the boundaries of the kinase active site in melanoma
RM Sammons, R Ghose, KY Tsai, KN Dalby
Molecular carcinogenesis 58 (9), 1551-1570, 2019
322019
From in silico discovery to intracellular activity: targeting JNK–protein interactions with small molecules
TS Kaoud, C Yan, S Mitra, CC Tseng, J Jose, JM Taliaferro, ...
ACS medicinal chemistry letters 3 (9), 721-725, 2012
302012
A novel class of common docking domain inhibitors that prevent ERK2 activation and substrate phosphorylation
RM Sammons, NA Perry, Y Li, EJ Cho, A Piserchio, DP Zamora-Olivares, ...
ACS chemical biology 14 (6), 1183-1194, 2019
292019
Modulating multi-functional ERK complexes by covalent targeting of a recruitment site in vivo
TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, D Zamora-Olivares, ...
Nature Communications 10 (1), 5232, 2019
202019
1, 3-diketone analogs as selective lysyl hydroxylase 2 (LH2) antagonists
J Lee, H Guo, Y Maghsoud, EA Vázquez-Montelongo, Z Jing, S Wang, ...
Available at SSRN 4314687, 2022
22022
A Toolbox of Structural Biology and Enzyme Kinetics Reveals the Case for ERK Docking Site Inhibition
RM Sammons, KN Dalby
Next Generation Kinase Inhibitors: Moving Beyond the ATP Binding/Catalytic …, 2020
12020
Discovery of a covalent inhibitor of ERK docking-interactions that inhibits A375 melanoma cells proliferation
TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, M Warthaka, M Cano, ...
Cancer Research 76 (14_Supplement), 3771-3771, 2016
12016
Preclinical development of JNK-targeted therapy for triple-negative breast cancer.
X Xie, TS Kaoud, R Edupuganti, RM Sammons, GN Hortobagyi, NT Ueno, ...
Cancer Research 73 (8_Supplement), 3241-3241, 2013
12013
Identification and biochemical characterization of small molecule inhibitors of ERK2 that target the D-recruitment site.
RM Sammons, EJ Cho, KN Dalby
Methods in Enzymology 690, 445-499, 2023
2023
High-Throughput Assay for Identifying Diverse Antagonists of the Binding Interaction between the ACE2 Receptor and the Dynamic Spike Proteins of SARS-CoV-2
RM Sammons, AL Bohanon, A Kowtha, A Dejong, EJ Cho, TS Kaoud, ...
ACS Infectious Diseases 8 (11), 2259-2270, 2022
2022
Cover Image, Volume 58, Issue 9
RM Sammons, R Ghose, KY Tsai, KN Dalby
Molecular Carcinogenesis 58 (9), i-i, 2019
2019
Targeting multi-functional ERK-protein complexes in vivo
TS Kaoud, WH Johnson, ND Ebelt, A Piserchio, D Zamora-Olivares, ...
Cancer Research 79 (13_Supplement), 3872-3872, 2019
2019
Inhibiting multifunctional ERK-protein complexes for cancer therapy
T Kaoud, WH Johnson, ND Ebelt, A Piserchio, SV Ravenstein, ...
EUROPEAN JOURNAL OF CANCER 103, E51-E51, 2018
2018
Unconventional approaches to kinase inhibition: covalent inhibitors and docking site inhibitors of mitogen-activated protein kinases
RM Sammons
2018
Silencing of ERK2 reverses EMT and suppresses the CSC phenotype, inhibiting lung metastasis in triple-negative breast cancer
MK Pitner, H Saso, R Larson, RM Sammons, H Chen, C Wei, G Chauhan, ...
Cancer Research 76 (14_Supplement), 1624-1624, 2016
2016
Covalent inhibition of ERK docking interactions
TS Kaoud, WH Johnson, A Piserchio, ND Ebelt, M Warthaka, M Cano, ...
The FASEB Journal 30, 856.11-856.11, 2016
2016
Inhibition of the TRPM7 kinase domain inhibits breast cancer cell migration and invasion and tumor metastasis
TS Kaoud, X Xie, J Park, CDJ Tavares, S Mitra, M Cano, RM Sammons, ...
Cancer Research 75 (15_Supplement), 3569-3569, 2015
2015
A high-throughput fluorescence anisotropy screening for discovery of inhibitors that target the D-recruitment site of ERK in vitro and in cells
RM Sammons, TS Kaoud, AK Devkota, EJ Cho, KN Dalby
Cancer Research 75 (15_Supplement), 3648-3648, 2015
2015
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