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Florian Bock
Florian Bock
Department of Radiotherapy, Maastricht University
Verified email at maastrichtuniversity.nl
Title
Cited by
Cited by
Year
Mitochondria as multifaceted regulators of cell death
FJ Bock, SWG Tait
Nature reviews Molecular cell biology 21 (2), 85-100, 2020
15212020
Mitochondrial permeabilization engages NF-κB-dependent anti-tumour activity under caspase deficiency
E Giampazolias, B Zunino, S Dhayade, F Bock, C Cloix, K Cao, A Roca, ...
Nature cell biology 19 (9), 1116-1129, 2017
2162017
Caspase-2 activation in the absence of PIDDosome formation
C Manzl, G Krumschnabel, F Bock, B Sohm, V Labi, F Baumgartner, ...
Journal of cell biology 185 (2), 291-303, 2009
1802009
The enigma of caspase-2: the laymen's view
G Krumschnabel, B Sohm, F Bock, C Manzl, A Villunger
Cell Death & Differentiation 16 (2), 195-207, 2009
1472009
RNA regulation by poly (ADP-ribose) polymerases
FJ Bock, TT Todorova, P Chang
Molecular cell 58 (6), 959-969, 2015
1072015
Caspase-2 at a glance
LL Fava, FJ Bock, S Geley, A Villunger
Journal of cell science 125 (24), 5911-5915, 2012
1072012
RETRACTED: DNA-PKcs-PIDDosome: A Nuclear Caspase-2-Activating Complex with Role in G2/M Checkpoint Maintenance
M Shi, CJ Vivian, KJ Lee, C Ge, K Morotomi-Yano, C Manzl, F Bock, ...
Cell 136 (3), 508-520, 2009
1062009
PARP13 regulates cellular mRNA post-transcriptionally and functions as a pro-apoptotic factor by destabilizing TRAILR4 transcript
T Todorova, FJ Bock, P Chang
Nature communications 5 (1), 5362, 2014
952014
New directions in poly (ADP‐ribose) polymerase biology
FJ Bock, P Chang
The FEBS journal 283 (22), 4017-4031, 2016
922016
BAX/BAK-induced apoptosis results in caspase-8-dependent IL-1β maturation in macrophages
D Chauhan, E Bartok, MM Gaidt, FJ Bock, J Herrmann, JM Seeger, P Broz, ...
Cell reports 25 (9), 2354-2368. e5, 2018
832018
Poly (ADP-ribose) polymerase-13 and RNA regulation in immunity and cancer
T Todorova, FJ Bock, P Chang
Trends in molecular medicine 21 (6), 373-384, 2015
772015
PIDDosome-independent tumor suppression by Caspase-2
C Manzl, L Peintner, G Krumschnabel, F Bock, V Labi, M Drach, ...
Cell Death & Differentiation 19 (10), 1722-1732, 2012
662012
Tight sequestration of BH3 proteins by BCL-xL at subcellular membranes contributes to apoptotic resistance
J Pécot, L Maillet, J Le Pen, C Vuillier, S de Carné Trécesson, A Fétiveau, ...
Cell reports 17 (12), 3347-3358, 2016
632016
Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome
C Manzl, LL Fava, G Krumschnabel, L Peintner, MC Tanzer, C Soratroi, ...
Cell death & disease 4 (12), e942-e942, 2013
392013
P53-induced protein with a death domain (PIDD): master of puppets?
FJ Bock, L Peintner, M Tanzer, C Manzl, A Villunger
Oncogene 31 (45), 4733-4739, 2012
352012
Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage
FJ Bock, G Krumschnabel, C Manzl, L Peintner, MC Tanzer, ...
Cell Death & Differentiation 20 (4), 546-557, 2013
322013
Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3‐only proteins Bim and Bmf
V Labi, D Bertele, C Woess, D Tischner, FJ Bock, S Schwemmers, ...
EMBO molecular medicine 5 (1), 122-136, 2013
322013
Apoptotic stress-induced FGF signalling promotes non-cell autonomous resistance to cell death
FJ Bock, E Sedov, E Koren, AL Koessinger, C Cloix, D Zerbst, D Athineos, ...
Nature communications 12 (1), 6572, 2021
302021
When cell death goes wrong: inflammatory outcomes of failed apoptosis and mitotic cell death
FJ Bock, JS Riley
Cell Death & Differentiation 30 (2), 293-303, 2023
222023
Increased apoptotic sensitivity of glioblastoma enables therapeutic targeting by BH3-mimetics
AL Koessinger, C Cloix, D Koessinger, DH Heiland, FJ Bock, K Strathdee, ...
Cell Death & Differentiation 29 (10), 2089-2104, 2022
122022
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