Steven Watterson

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Peter GhazalCardiff University, School of MedicineVerified email at cardiff.ac.uk
William J GriffithsSwansea UniversityVerified email at swansea.ac.uk
Andrew PartonMultiomic HealthVerified email at multiomic.health
Anthony John BjoursonProfessor of Genomics, Northern Ireland Centre for Stratified Medicine, Ulster UniversityVerified email at ulster.ac.uk
Markus R WenkDepartment of Biochemistry, National University of SIngaporeVerified email at nus.edu.sg
Aaron PeaceVisiting Professor University of UlsterVerified email at c-tric.com
yuqin wangSwansea University Medical SchoolVerified email at swansea.ac.uk
Alexander MazeinLuxembourg Centre for Systems Biomedicine, University of LuxembourgVerified email at uni.lu
Kai A KroppHannover Medical SchoolVerified email at mh-hannover.de
Tom C. FreemanProfessor of Systems Immunology, University of EdinburghVerified email at roslin.ed.ac.uk
glass ckProfessor Cellular and Molecular Medicine UC San DiegoVerified email at ucsd.edu
Holly C GibbsResearch Assistant Professor, Texas A&M UniversityVerified email at tamu.edu
Mizanur KhondokerAssociate Professor in Medical Statistics, University of East Anglia, UKVerified email at uea.ac.uk
Garwin Kim SingAlfaisal UniversityVerified email at alfaisal.edu
Timothy OsborneProfessor of Medicine, Biological Chemistry and Pediatrics Johns Hopkins MedicineVerified email at jh.edu
Sobia RazaHead of Science, PHG FoundationVerified email at medschl.cam.ac.uk
Ozgur AkmanAssociate Professor of Mathematics for Biology and MedicineVerified email at exeter.ac.uk
Andrew J. MillarUniversity of EdinburghVerified email at ed.ac.uk
Jane HillstonProfessor of Quantitative Modelling, University of EdinburghVerified email at ed.ac.uk
Maria Luisa GuerrieroData Sciences and Quantitative Biology, Biopharmaceuticals R&D, AstraZenecaVerified email at astrazeneca.com

Steven Watterson

Lecturer in Computational Biology, Ulster University

Verified email at ulster.ac.uk - Homepage

Systems Biology Computational Biology Cardiovascular Disease Cholesterol Metabolism Personalised Medicine


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The systems biology graphical notation N Le Novere, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ... Nature biotechnology 27 (8), 735-741, 2009	991	2009
The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, ... Immunity 38 (1), 106-118, 2013	349	2013
Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis M Blanc, WY Hsieh, KA Robertson, S Watterson, G Shui, P Lacaze, ... PLoS-Biology 9 (3), 455, 2011	270	2011
The genetics and screening of familial hypercholesterolaemia R Henderson, M O’Kane, V McGilligan, S Watterson Journal of Biomedical Science 23 (1), 39, 2016	150	2016
Propionibacterium acnes and Acne Vulgaris: New Insights from the Integration of Population Genetic, Multi-Omic, Biochemical and Host-Microbe Studies J McLaughlin, S Watterson, AM Layton, AJ Bjourson, E Barnard, ... Microorganisms 7 (5), 128, 2019	132	2019
A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway A Mazein, S Watterson, WY Hsieh, WJ Griffiths, P Ghazal Biochemical Pharmacology 86 (1), 56-66, 2013	83	2013
Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms A Mazein, M Ostaszewski, I Kuperstein, S Watterson, N Le Novère, ... NPJ systems biology and applications 4 (1), 21, 2018	80	2018
Digital clocks: simple Boolean models can quantitatively describe circadian systems OE Akman, S Watterson, A Parton, N Binns, AJ Millar, P Ghazal Journal of The Royal Society Interface 9 (74), 2365-2382, 2012	80	2012
Logic models of pathway biology S Watterson, S Marshall, P Ghazal Drug discovery today 13 (9-10), 447-456, 2008	75	2008
Computational modelling of atherosclerosis A Parton, V McGilligan, M O’Kane, FR Baldrick, S Watterson Briefings in Bioinformatics 17 (4), 562-575, 2016	58	2016
Construction of a large scale integrated map of macrophage pathogen recognition and effector systems S Raza, N McDerment, PA Lacaze, K Robertson, S Watterson, Y Chen, ... BMC systems biology 4 (1), 1-18, 2010	50	2010
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway KA Robertson, WY Hsieh, T Forster, M Blanc, H Lu, PJ Crick, E Yutuc, ... PLoS Biol 14 (3), e1002364, 2016	44	2016
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction S Watterson, ML Guerriero, M Blanc, A Mazein, L Loewe, KA Robertson, ... Biochimie 95 (3), 613-621, 2013	35	2013
Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events M Chemaly, V McGilligan, M Gibson, M Clauss, S Watterson, ... Archives of cardiovascular diseases 110 (12), 700-711, 2017	30	2017
Rapid proteasomal elimination of 3-hydroxy-3-methylglutaryl-CoA reductase by interferon-γ in primary macrophages requires endogenous 25-hydroxycholesterol synthesis H Lu, S Talbot, KA Robertson, S Watterson, T Forster, D Roy, P Ghazal Steroids 99, 219-229, 2015	30	2015
Deep Learning in Systems Medicine E Pujos-Guillot, B Comte, JL de Miranda, V Spiwok, I Chorbev, ... Briefings in Bioinformatics 22 (2), 1543-1559, 2021	21*	2021
New models of atherosclerosis and multi-drug therapeutic interventions. A Parton, V McGilligan, M Chemaly, M O’Kane, S Watterson Bioinformatics 35 (14), 2449-2457, 2018	21	2018
Network and systems medicine: Position paper of the European Collaboration on Science and Technology action on Open Multiscale Systems Medicine B Comte, J Baumbach, A Benis, J Basílio, N Debeljak, Å Flobak, ... Network and Systems Medicine 3 (1), 67-90, 2020	19	2020
Use of logic theory in understanding regulatory pathway signaling in response to infection S Watterson, P Ghazal Future Microbiology 5 (2), 163-176, 2010	18	2010
The Interdependency and Co-Regulation of the Vitamin D and Cholesterol Metabolism T Warren, R McAllister, A Morgan, TS Rai, V McGilligan, M Ennis, C Page, ... Cells 10 (8), 2007, 2021	14	2021

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