Follow
Balamurugan Dhayalan
Balamurugan Dhayalan
Assistant Research Professor, Indiana University
Verified email at iu.edu - Homepage
Title
Cited by
Cited by
Year
‘Smart’insulin-delivery technologies and intrinsic glucose-responsive insulin analogues
MA Jarosinski, B Dhayalan, N Rege, D Chatterjee, MA Weiss
Diabetologia 64, 1016-1029, 2021
602021
Evolution of insulin at the edge of foldability and its medical implications
NK Rege, M Liu, Y Yang, B Dhayalan, NP Wickramasinghe, YS Chen, ...
Proceedings of the National Academy of Sciences 117 (47), 29618-29628, 2020
292020
Obviation of hydrogen fluoride in Boc chemistry solid phase peptide synthesis of peptide-α thioesters
ZP Gates, B Dhayalan, SBH Kent
Chemical Communications 52 (97), 13979-13982, 2016
252016
Efficient Total Chemical Synthesis of 13C=18O Isotopomers of Human Insulin for Isotope‐Edited FTIR
B Dhayalan, A Fitzpatrick, K Mandal, J Whittaker, MA Weiss, A Tokmakoff, ...
ChemBioChem 17 (5), 415-420, 2016
242016
Role of proinsulin self-association in mutant INS gene–induced diabetes of youth
J Sun, Y Xiong, X Li, L Haataja, W Chen, SA Mir, L Lv, R Madley, D Larkin, ...
Diabetes 69 (5), 954-964, 2020
232020
Scope & Limitations of Fmoc Chemistry SPPS‐Based Approaches to the Total Synthesis of Insulin Lispro via Ester Insulin
B Dhayalan, K Mandal, N Rege, M Weiss, S Eitel, T Meier, R Schoenleber, ...
Chemistry-A European Journal, 2016
232016
Unprecedented Torsional Preferences in trans‐β2,3‐Amino Acid Residues and Formation of 11‐Helices in α,β2,3‐Hybrid Peptides
D Balamurugan, KM Muraleedharan
Chemistry–A European Journal 18 (31), 9516-9520, 2012
232012
Distinct states of proinsulin misfolding in MIDY
L Haataja, A Arunagiri, A Hassan, K Regan, B Tsai, B Dhayalan, ...
Cellular and Molecular Life Sciences 78, 6017-6031, 2021
212021
Insertion of a synthetic switch into insulin provides metabolite-dependent regulation of hormone–receptor activation
YS Chen, J Gleaton, Y Yang, B Dhayalan, NB Phillips, Y Liu, ...
Proceedings of the National Academy of Sciences 118 (30), e2103518118, 2021
212021
Structural principles of insulin formulation and analog design: A century of innovation
MA Jarosinski, B Dhayalan, YS Chen, D Chatterjee, N Varas, MA Weiss
Molecular Metabolism 52, 101325, 2021
192021
Crystallization of Enantiomerically Pure Proteins from Quasi‐Racemic Mixtures: Structure Determination by X‐Ray Diffraction of Isotope‐Labeled Ester Insulin and Human Insulin
K Mandal, B Dhayalan, M Avital‐Shmilovici, A Tokmakoff, SBH Kent
ChemBioChem 17 (5), 421-425, 2016
192016
Refinement of Peptide Conformational Ensembles by 2D IR Spectroscopy: Application to Ala‒Ala‒Ala
CJ Feng, B Dhayalan, A Tokmakoff
Biophysical journal 114 (12), 2820-2832, 2018
182018
Reassessment of an innovative insulin analogue excludes protracted action yet highlights the distinction between external and internal diselenide bridges
B Dhayalan, YS Chen, NB Phillips, M Swain, NK Rege, A Mirsalehi, ...
Chemistry–A European Journal 26 (21), 4695-4700, 2020
132020
Enhanced solvation of peptides attached to “solid-phase” resins: straightforward syntheses of the elastin sequence Pro-Gly-Val-Gly-Val-Pro-Gly-Val-Gly-Val
B Dang, B Dhayalan, SBH Kent
Organic letters 17 (14), 3521-3523, 2015
132015
An efficient synthetic approach towards trans-β2, 3-amino acids and demonstration of their utility in the design of therapeutically important β2, 3-peptides and α, β2, 3 …
D Balamurugan, KM Muraleedharan
Tetrahedron 65 (48), 10074-10082, 2009
122009
“Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution
NK Rege, M Liu, B Dhayalan, YS Chen, NA Smith, L Rahimi, J Sun, ...
Journal of Biological Chemistry 295 (10), 3080-3098, 2020
112020
Can Helical Peptides Unwind One Turn at a Time? ‐ Controlled Conformational Transitions in α,β2,3‐Hybrid Peptides
D Balamurugan, KM Muraleedharan
Chemistry–A European Journal 21 (26), 9332-9338, 2015
102015
Structural lessons from the mutant proinsulin syndrome
B Dhayalan, D Chatterjee, YS Chen, MA Weiss
Frontiers in Endocrinology 12, 754693, 2021
92021
New horizons: next-generation insulin analogues: structural principles and clinical goals
MA Jarosinski, YS Chen, N Varas, B Dhayalan, D Chatterjee, MA Weiss
The Journal of Clinical Endocrinology & Metabolism 107 (4), 909-928, 2022
72022
Chemical environment as control element in the evolution of shapes–‘hexagons and rods’ from an 11-helical α, β 2, 3-hybrid peptide
D Balamurugan, KM Muraleedharan
Soft Matter 8 (47), 11857-11862, 2012
52012
The system can't perform the operation now. Try again later.
Articles 1–20