Follow
Parthasarathy Chandrakesan
Parthasarathy Chandrakesan
Director Research & Development, Wild Earth, Former Associate Professor, Member of Stepenson Cancer
Verified email at wildearth.com
Title
Cited by
Cited by
Year
Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity
KS Yan, O Gevaert, GXY Zheng, B Anchang, CS Probert, KA Larkin, ...
Cell stem cell 21 (1), 78-90. e6, 2017
3412017
DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer
SM Sureban, R May, D Qu, N Weygant, P Chandrakesan, N Ali, ...
PloS one 8 (9), e73940, 2013
1532013
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1
N Weygant, D Qu, WL Berry, R May, P Chandrakesan, DB Owen, ...
Molecular cancer 13, 1-14, 2014
1232014
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism
SM Sureban, R May, N Weygant, D Qu, P Chandrakesan, ...
Cancer letters 351 (1), 151-161, 2014
1232014
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells
P Chandrakesan, J Yao, D Qu, R May, N Weygant, Y Ge, N Ali, ...
Molecular Cancer 16, 1-14, 2017
1072017
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma
N Weygant, D Qu, R May, RM Tierney, WL Berry, L Zhao, S Agarwal, ...
Oncotarget 6 (4), 2193, 2015
922015
Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury
R May, D Qu, N Weygant, P Chandrakesan, N Ali, SA Lightfoot, L Li, ...
Stem cells 32 (3), 822-827, 2014
882014
DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition.
P Chandrakesan, N Weygant, R May, D Qu, HR Chinthalapally, ...
Oncotarget 5 (19), 9269-9280, 2014
832014
Utility of a bacterial infection model to study epithelial–mesenchymal transition, mesenchymal–epithelial transition or tumorigenesis
P Chandrakesan, B Roy, L Jakkula, I Ahmed, P Ramamoorthy, O Tawfik, ...
Oncogene 33 (20), 2639-2654, 2014
752014
Ablation of doublecortin-like kinase 1 in the colonic epithelium exacerbates dextran sulfate sodium-induced colitis
D Qu, N Weygant, R May, P Chandrakesan, M Madhoun, N Ali, ...
PLoS One 10 (8), e0134212, 2015
702015
Chemopreventive effect of bacoside A on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats
P Janani, K Sivakumari, A Geetha, B Ravisankar, C Parthasarathy
Journal of cancer research and clinical oncology 136, 759-770, 2010
692010
Diethylhexyl phthalate impairs insulin binding and glucose oxidation in Chang liver cells
S Rengarajan, C Parthasarathy, M Anitha, K Balasubramanian
Toxicology in vitro 21 (1), 99-102, 2007
632007
Critical roles of Notch and Wnt/β-catenin pathways in the regulation of hyperplasia and/or colitis in response to bacterial infection
I Ahmed, P Chandrakesan, O Tawfik, L Xia, S Anant, S Umar
Infection and immunity 80 (9), 3107-3121, 2012
622012
Hepatoprotective activity of bacoside A against N-nitrosodiethylamine-induced liver toxicity in adult rats
P Janani, K Sivakumari, C Parthasarathy
Cell biology and toxicology 25, 425-434, 2009
592009
Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism
SM Sureban, MF Madhoun, R May, D Qu, N Ali, J Fazili, N Weygant, ...
Oncotarget 6 (35), 37200, 2015
582015
Novel changes in NF-κB activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38
P Chandrakesan, I Ahmed, T Anwar, Y Wang, S Sarkar, P Singh, S Peleg, ...
Journal of biological chemistry 285 (43), 33485-33498, 2010
572010
Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer
Y Ge, N Weygant, D Qu, R May, WL Berry, J Yao, P Chandrakesan, ...
International journal of cancer 143 (5), 1162-1175, 2018
562018
Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells
D Qu, J Johnson, P Chandrakesan, N Weygant, R May, N Aiello, A Rhim, ...
PloS one 10 (2), e0118933, 2015
552015
Regulatory roles of Dclk1 in epithelial mesenchymal transition and cancer stem cells
P Chandrakesan, J Panneerselvam, D Qu, N Weygant, R May, MS Bronze, ...
Journal of carcinogenesis & mutagenesis 7 (2), 2016
502016
Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal
P Chandrakesan, R May, D Qu, N Weygant, VE Taylor, JD Li, N Ali, ...
Oncotarget 6 (31), 30876, 2015
472015
The system can't perform the operation now. Try again later.
Articles 1–20