Turgut Dogruluk
Turgut Dogruluk
Exact Sciences
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Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer
H Liang, LWT Cheung, J Li, Z Ju, S Yu, K Stemke-Hale, T Dogruluk, Y Lu, ...
Genome research 22 (11), 2120-2129, 2012
Systematic functional annotation of somatic mutations in cancer
PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ...
Cancer cell 33 (3), 450-462. e10, 2018
Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations
T Dogruluk, YH Tsang, M Espitia, F Chen, T Chen, Z Chong, V Appadurai, ...
Cancer research 75 (24), 5341-5354, 2015
Moesin Is a Glioma Progression Marker That Induces Proliferation and Wnt/β-Catenin Pathway Activation via Interaction with CD44The Moesin-CD44 Oncogenic Complex: New Target in …
X Zhu, FC Morales, NK Agarwal, T Dogruluk, M Gagea, MM Georgescu
Cancer research 73 (3), 1142-1155, 2013
HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome
J Wardwell-Ozgo, T Dogruluk, A Gifford, Y Zhang, TP Heffernan, ...
Oncogene 33 (8), 1017-1026, 2014
Functional annotation of rare gene aberration drivers of pancreatic cancer
YH Tsang, T Dogruluk, PM Tedeschi, J Wardwell-Ozgo, H Lu, M Espitia, ...
Nature communications 7 (1), 1-11, 2016
Characterization of cancer stem-like cells in chordoma
E Aydemir, OF Bayrak, F Sahin, B Atalay, GT Kose, M Ozen, S Sevli, ...
Journal of neurosurgery 116 (4), 810-820, 2012
Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules
H Guo, M Gao, Y Lu, J Liang, PL Lorenzi, S Bai, DH Hawke, J Li, ...
Oncogene 33 (26), 3463-3472, 2014
Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of CancerEngineering and Functional Annotation of Cancer Fusion Genes
H Lu, N Villafane, T Dogruluk, CL Grzeskowiak, K Kong, YH Tsang, ...
Cancer research 77 (13), 3502-3512, 2017
Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression
YH Tsang, Y Wang, K Kong, C Grzeskowiak, O Zagorodna, T Dogruluk, ...
Elife 9, e48963, 2020
A functional genomic approach to actionable gene fusions for precision oncology
J Li, H Lu, PKS Ng, A Pantazi, CKM Ip, KJ Jeong, B Amador, R Tran, ...
Science advances 8 (6), eabm2382, 2022
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