| The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching S Suchting, C Freitas, F le Noble, R Benedito, C Bréant, A Duarte, ... Proceedings of the National Academy of Sciences 104 (9), 3225-3230, 2007 | 1011 | 2007 |
| Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation T Tammela, G Zarkada, E Wallgard, A Murtomäki, S Suchting, ... Nature 454 (7204), 656-660, 2008 | 985 | 2008 |
| Dosage-sensitive requirement for mouse Dll4 in artery development A Duarte, M Hirashima, R Benedito, A Trindade, P Diniz, E Bekman, ... Genes & development 18 (20), 2474-2478, 2004 | 726 | 2004 |
| Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment U Koch, E Fiorini, R Benedito, V Besseyrias, K Schuster-Gossler, ... The Journal of experimental medicine 205 (11), 2515-2523, 2008 | 534 | 2008 |
| Identification and functional analysis of endothelial tip cell–enriched genes R del Toro, C Prahst, T Mathivet, G Siegfried, JS Kaminker, B Larrivee, ... Blood, The Journal of the American Society of Hematology 116 (19), 4025-4033, 2010 | 485 | 2010 |
| Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF–VEGFR2 signalling R Benedito, SF Rocha, M Woeste, M Zamykal, F Radtke, O Casanovas, ... Nature 484 (7392), 110-114, 2012 | 430 | 2012 |
| ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway B Larrivée, C Prahst, E Gordon, R del Toro, T Mathivet, A Duarte, ... Developmental cell 22 (3), 489-500, 2012 | 415 | 2012 |
| Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion JS Scehnet, W Jiang, S Ram Kumar, V Krasnoperov, A Trindade, ... Blood, The Journal of the American Society of Hematology 109 (11), 4753-4760, 2007 | 348 | 2007 |
| The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development S Seo, H Fujita, A Nakano, M Kang, A Duarte, T Kume Developmental biology 294 (2), 458-470, 2006 | 329 | 2006 |
| RNA binding by the Wilms tumor suppressor zinc finger proteins. A Caricasole, A Duarte, SH Larsson, ND Hastie, M Little, G Holmes, ... Proceedings of the National Academy of Sciences 93 (15), 7562-7566, 1996 | 265 | 1996 |
| Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos A Trindade, S Ram Kumar, JS Scehnet, L Lopes-da-Costa, J Becker, ... Blood, The Journal of the American Society of Hematology 112 (5), 1720-1729, 2008 | 166 | 2008 |
| Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles R Benedito, A Duarte Gene expression patterns 5 (6), 750-755, 2005 | 150 | 2005 |
| Endothelial Jagged1 antagonizes Dll4 regulation of endothelial branching and promotes vascular maturation downstream of Dll4/Notch1 AR Pedrosa, A Trindade, AC Fernandes, C Carvalho, J Gigante, ... Arteriosclerosis, thrombosis, and vascular biology 35 (5), 1134-1146, 2015 | 137 | 2015 |
| Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis D Djokovic, A Trindade, J Gigante, M Badenes, L Silva, R Liu, X Li, ... BMC cancer 10, 1-12, 2010 | 119 | 2010 |
| miR-21 ablation and obeticholic acid ameliorate nonalcoholic steatohepatitis in mice PM Rodrigues, MB Afonso, AL Simão, CC Carvalho, A Trindade, A Duarte, ... Cell death & disease 8 (4), e2748-e2748, 2017 | 118 | 2017 |
| Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli R Benedito, A Trindade, M Hirashima, D Henrique, LL Da Costa, ... BMC developmental biology 8, 1-15, 2008 | 98 | 2008 |
| Dll4-Notch signaling determines the formation of native arterial collateral networks and arterial function in mouse ischemia models B Cristofaro, Y Shi, M Faria, S Suchting, AS Leroyer, A Trindade, A Duarte, ... Development 140 (8), 1720-1729, 2013 | 82 | 2013 |
| Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions AR Pedrosa, A Trindade, C Carvalho, J Graça, S Carvalho, MC Peleteiro, ... Oncotarget 6 (27), 24404, 2015 | 75 | 2015 |
| Notch1 is pan-endothelial at the onset of flow and regulated by flow ED Jahnsen, A Trindade, HC Zaun, S Lehoux, A Duarte, EAV Jones PloS one 10 (4), e0122622, 2015 | 75 | 2015 |
| Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle D Murta, M Batista, E Silva, A Trindade, D Henrique, A Duarte, ... PloS one 8 (8), e72767, 2013 | 68 | 2013 |
Alexandre TrindadeAssociate Professor, Egas Moniz School of Health & ScienceVerified email at egasmoniz.edu.pt
