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Whijae Roh
Whijae Roh
Senior Computational Biologist, Pfizer
Verified email at pfizer.com - Homepage
Title
Cited by
Cited by
Year
Clonal evolution in breast cancer revealed by single nucleus genome sequencing
Y Wang, J Waters, ML Leung, A Unruh, W Roh, X Shi, K Chen, P Scheet, ...
Nature 512 (7513), 155-160, 2014
11402014
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade
PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ...
Cancer discovery 6 (8), 827-837, 2016
9252016
Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance
W Roh, PL Chen, A Reuben, CN Spencer, PA Prieto, JP Miller, ...
Science translational medicine 9 (379), eaah3560, 2017
7582017
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
MC Andrews, CPM Duong, V Gopalakrishnan, V Iebba, WS Chen, ...
Nature medicine 27 (8), 1432-1441, 2021
2502021
Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma
A Reuben, CN Spencer, PA Prieto, V Gopalakrishnan, SM Reddy, ...
NPJ genomic medicine 2 (1), 10, 2017
1312017
The lipogenic regulator SREBP2 induces transferrin in circulating melanoma cells and suppresses ferroptosis
X Hong, W Roh, RJ Sullivan, KHK Wong, BS Wittner, H Guo, TD Dubash, ...
Cancer discovery 11 (3), 678-695, 2021
1282021
The natural anticancer agent plumbagin induces potent cytotoxicity in MCF-7 human breast cancer cells by inhibiting a PI-5 kinase for ROS generation
JH Lee, JH Yeon, H Kim, W Roh, J Chae, HO Park, DM Kim
Public Library of Science 7 (9), e45023, 2012
902012
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers
R Bill, P Wirapati, M Messemaker, W Roh, B Zitti, F Duval, M Kiss, JC Park, ...
Science 381 (6657), 515-524, 2023
632023
A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 …
G Romano, PL Chen, P Song, JL McQuade, RJ Liang, M Liu, W Roh, ...
Cancer discovery 8 (5), 556-567, 2018
592018
Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity
WC Lee, A Reuben, X Hu, N McGranahan, R Chen, A Jalali, MV Negrao, ...
Genome biology 21, 1-21, 2020
412020
Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma
A Mitra, MC Andrews, W Roh, MP De Macedo, CW Hudgens, F Carapeto, ...
Nature communications 11 (1), 1839, 2020
222020
Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer
N Vidula, T Dubash, MS Lawrence, A Simoneau, A Niemierko, E Blouch, ...
Clinical Cancer Research 26 (18), 4852-4862, 2020
142020
High-resolution profiling of lung adenocarcinoma identifies expression subtypes with specific biomarkers and clinically relevant vulnerabilities
W Roh, Y Geffen, H Cha, M Miller, S Anand, J Kim, DI Heiman, JF Gainor, ...
Cancer research 82 (21), 3917-3931, 2022
122022
Clonal evolution of acute myeloid leukemia relapsed after 19 years of remission
K Takahashi, W Roh, J Zhang, A Propotopov, K Patel, S Strickland, A Kim, ...
American journal of hematology 90 (7), E134, 2015
72015
External compression-induced fracture patterning on the surface of poly (dimethylsiloxane) cubes and microspheres
T Uchida, KL Mills, CH Kuo, W Roh, YC Tung, AL Garner, K Koide, ...
Langmuir 25 (5), 3102-3107, 2009
72009
Molecular and immune heterogeneity in synchronous melanoma metastases
A Reuben, C Spencer, J Roszik, J Miller, L Kwong, H Jiang, C Haymaker, ...
Journal for immunotherapy of cancer 3, 1-1, 2015
52015
Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade
J Wargo, M Andrews, C Duong, V Gopalakrishnan, V Iebba, WS Chen, ...
22020
Comprehensive molecular profiling of primary tumors and paired distant metastases in non-small cell lung cancer
WC Lee, D Gomez, J Zhang, A Reuben, A Jalali, W Roh, CC Wu, W Lu, ...
Cancer Research 79 (13_Supplement), 2741-2741, 2019
12019
Multi-spatial whole-lesion molecular heterogeneity of an immunotherapy-resistant metastatic melanoma.
A Mitra, W Roh, A Reuben, M Macedo, FCL Carapeto, C Gumbs, J Zhang, ...
Journal of Clinical Oncology 36 (15_suppl), 9568-9568, 2018
12018
Abstract CT231: Identification of a novel agnostic predictive multiomic signature via Elastic Net/Machine Learning in TALAPRO-2 (TP-2), a phase 3 study of talazoparib (TALA)+ …
G Liu, XJ Mu, K Fizazi, AD Laird, N Matsubara, SM Yip, J Pu, J Carles, ...
Cancer Research 84 (7_Supplement), CT231-CT231, 2024
2024
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