Activation of Wnt signaling by mechanical loading is impaired in the bone of old mice N Holguin, MD Brodt, MJ Silva Journal of Bone and Mineral Research 31 (12), 2215-2226, 2016 | 154 | 2016 |
Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury H Yan, X Duan, H Pan, N Holguin, MF Rai, A Akk, LE Springer, ... Proceedings of the National Academy of Sciences 113 (41), E6199-E6208, 2016 | 152 | 2016 |
Aging diminishes lamellar and woven bone formation induced by tibial compression in adult C57BL/6 N Holguin, MD Brodt, ME Sanchez, MJ Silva Bone 65, 83-91, 2014 | 144 | 2014 |
Short applications of very low-magnitude vibrations attenuate expansion of the intervertebral disc during extended bed rest N Holguin, J Muir, C Rubin, S Judex The Spine Journal 9 (6), 470-477, 2009 | 107 | 2009 |
mTORC2 signaling promotes skeletal growth and bone formation in mice J Chen, N Holguin, Y Shi, MJ Silva, F Long Journal of Bone and Mineral Research 30 (2), 369-378, 2015 | 97 | 2015 |
Early response of mouse joint tissue to noninvasive knee injury suggests treatment targets P Wu, N Holguin, MJ Silva, M Fu, W Liao, LJ Sandell Arthritis & rheumatology 66 (5), 1256-1265, 2014 | 74 | 2014 |
Adaptation of tibial structure and strength to axial compression depends on loading history in both C57BL/6 and BALB/c mice N Holguin, MD Brodt, ME Sanchez, AA Kotiya, MJ Silva Calcified tissue international 93, 211-221, 2013 | 67 | 2013 |
Post-traumatic osteoarthritis in mice following mechanical injury to the synovial joint MF Rai, X Duan, JD Quirk, N Holguin, EJ Schmidt, N Chinzei, MJ Silva, ... Scientific reports 7 (1), 45223, 2017 | 63 | 2017 |
Evaluation of loading parameters for murine axial tibial loading: Stimulating cortical bone formation while reducing loading duration D Sun, MD Brodt, HM Zannit, N Holguin, MJ Silva Journal of Orthopaedic Research® 36 (2), 682-691, 2018 | 55 | 2018 |
Brief daily exposure to low-intensity vibration mitigates the degradation of the intervertebral disc in a frequency-specific manner N Holguin, G Uzer, FP Chiang, C Rubin, S Judex Journal of applied physiology 111 (6), 1846-1853, 2011 | 53 | 2011 |
In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via Wnt/Beta-Catenin Signaling N Holguin, MJ Silva Scientific reports 8 (1), 11191, 2018 | 44 | 2018 |
Aging aggravates intervertebral disc degeneration by regulating transcription factors toward chondrogenesis MJ Silva, N Holguin FASEB journal: official publication of the Federation of American Societies …, 2020 | 42 | 2020 |
The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice N Holguin, R Aguilar, RA Harland, BA Bomar, MJ Silva Journal of Applied Physiology 116 (12), 1551-1560, 2014 | 37 | 2014 |
Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading X Duan, LJ Sandell, N Chinzei, N Holguin, MJ Silva, A Schiavinato, ... PLoS One 12 (4), e0175682, 2017 | 28 | 2017 |
Rat intervertebral disc health during hindlimb unloading: brief ambulation with or without vibration N Holguin, S Judex Aviation, space, and environmental medicine 81 (12), 1078-1084, 2010 | 25 | 2010 |
Low-intensity vibrations partially maintain intervertebral disc mechanics and spinal muscle area during deconditioning N Holguin, JT Martin, DM Elliott, S Judex The Spine Journal 13 (4), 428-436, 2013 | 24 | 2013 |
Early changes in the knee of healer and non‐healer mice following non‐invasive mechanical injury X Duan, MF Rai, N Holguin, MJ Silva, D Patra, W Liao, LJ Sandell Journal of Orthopaedic Research 35 (3), 524-536, 2017 | 18 | 2017 |
Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization–an in vivo rat model D Wang, A Lai, J Gansau, AC Seifert, J Munitz, K Zaheer, N Bhadouria, ... The Spine Journal 23 (9), 1375-1388, 2023 | 14 | 2023 |
Suppression of Sost/Sclerostin and Dickkopf‐1 augment intervertebral disc structure in mice T Kroon, N Bhadouria, P Niziolek, D Edwards III, R Choi, EL Clinkenbeard, ... Journal of Bone and Mineral Research 37 (6), 1156-1169, 2020 | 9 | 2020 |
CORRInsights®: The NLRP3/Caspase-1/Interleukin-1β Axis Is Active in Human Lumbar Cartilaginous Endplate Degeneration N Holguin Clinical Orthopaedics and Related Research® 474 (8), 1827-1829, 2016 | 3 | 2016 |