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Smriti Sangwan
Smriti Sangwan
Post Doctoral Scholar, UCSF
Verified email at walterlab.ucsf.edu
Title
Cited by
Cited by
Year
Structure of the toxic core of α-synuclein from invisible crystals
JA Rodriguez, MI Ivanova, MR Sawaya, D Cascio, FE Reyes, D Shi, ...
Nature 525 (7570), 486-490, 2015
6052015
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
5982020
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473-1479, 2020
3622020
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)
S Sangwan, A Zhao, KL Adams, CK Jayson, MR Sawaya, EL Guenther, ...
Proceedings of the National Academy of Sciences 114 (33), 8770-8775, 2017
1102017
Crystal structures of IAPP amyloidogenic segments reveal a novel packing motif of out-of-register beta sheets
AB Soriaga, S Sangwan, R Macdonald, MR Sawaya, D Eisenberg
The Journal of Physical Chemistry B 120 (26), 5810-5816, 2016
702016
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
BioRxiv, 2020
602020
Inhibition of synucleinopathic seeding by rationally designed inhibitors
S Sangwan, S Sahay, KA Murray, S Morgan, EL Guenther, L Jiang, ...
Elife 9, e46775, 2020
552020
Perspective on SOD1 mediated toxicity in Amyotrophic Lateral Sclerosis
S Sangwan, DS Eisenberg
Postępy Biochemii 62 (3), 362-369, 2016
372016
Factors that drive peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants
TD Do, NE LaPointe, S Sangwan, DB Teplow, SC Feinstein, MR Sawaya, ...
The Journal of Physical Chemistry B 118 (26), 7247-7256, 2014
322014
Atomic structures of corkscrew‐forming segments of SOD1 reveal varied oligomer conformations
S Sangwan, MR Sawaya, KA Murray, MP Hughes, DS Eisenberg
Protein Science 27 (7), 1231-1242, 2018
222018
Distal amyloid β‐protein fragments template amyloid assembly
TD Do, S Sangwan, NEC de Almeida, AI Ilitchev, M Giammona, ...
Protein Science 27 (7), 1181-1190, 2018
122018
Consortium QSB, Walter P, Manglik A
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473, 2020
102020
A Legionella toxin mimics tRNA and glycosylates the translation machinery to trigger a ribotoxic stress response
A Subramanian, L Wang, T Moss, M Voorhies, S Sangwan, E Stevenson, ...
bioRxiv, 2022.06. 10.495705, 2022
32022
A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
A Subramanian, L Wang, T Moss, M Voorhies, S Sangwan, E Stevenson, ...
Nature Cell Biology 25 (11), 1600-1615, 2023
22023
Structure-based peptide inhibitors of alpha-synuclein aggregation
DS Eisenberg, S Sangwan, L Jiang
US Patent App. 17/848,736, 2023
12023
Full wwPDB X-ray Structure Validation Report i
Y Kim, KH Kim
12023
A helical fulcrum in eIF2B coordinates allosteric regulation of stress signaling
RE Lawrence, SR Shoemaker, A Deal, S Sangwan, AA Anand, L Wang, ...
Nature Chemical Biology, 1-10, 2023
2023
A central helical fulcrum in eIF2B coordinates allosteric regulation of Integrated Stress Response signaling
RE Lawrence, S Shoemaker, A Deal, S Sangwan, A Anand, L Wang, ...
bioRxiv, 2022.12. 22.521453, 2022
2022
Structure-based peptide inhibitors of alpha-synuclein aggregation
DS Eisenberg, S Sangwan, L Jiang
US Patent 10,815,271, 2020
2020
An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation (preprint)
M Schoof, B Faust, RA Saunders, S Sangwan, VV Rezelj, N Hoppe, ...
2020
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