| Human Rev1 polymerase disrupts G-quadruplex DNA S Eddy, A Ketkar, MK Zafar, L Maddukuri, JY Choi, RL Eoff Nucleic acids research 42 (5), 3272-3285, 2014 | 77 | 2014 |
| Kinetic analysis of human PrimPol DNA polymerase activity reveals a generally error-prone enzyme capable of accurately bypassing 7, 8-dihydro-8-oxo-2′-deoxyguanosine MK Zafar, A Ketkar, MF Lodeiro, CE Cameron, RL Eoff Biochemistry 53 (41), 6584-6594, 2014 | 66 | 2014 |
| Synthesis and biological evaluation of novel 4, 5-disubstituted 2H-1, 2, 3-triazoles as cis-constrained analogues of combretastatin A-4 NR Madadi, NR Penthala, K Howk, A Ketkar, RL Eoff, MJ Borrelli, ... European journal of medicinal chemistry 103, 123-132, 2015 | 64 | 2015 |
| Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA S Eddy, L Maddukuri, A Ketkar, MK Zafar, EE Henninger, ZF Pursell, ... Biochemistry 54 (20), 3218-3230, 2015 | 48 | 2015 |
| 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1) NR Penthala, A Ketkar, KR Sekhar, ML Freeman, RL Eoff, R Balusu, ... Bioorganic & medicinal chemistry 23 (22), 7226-7233, 2015 | 42 | 2015 |
| Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK CC Hsu, X Zhang, G Wang, W Zhang, Z Cai, BS Pan, H Gu, C Xu, G Jin, ... Molecular cell 81 (18), 3803-3819. e7, 2021 | 41 | 2021 |
| Human translesion polymerase κ exhibits enhanced activity and reduced fidelity two nucleotides from G-quadruplex DNA S Eddy, M Tillman, L Maddukuri, A Ketkar, MK Zafar, RL Eoff Biochemistry 55 (37), 5218-5229, 2016 | 41 | 2016 |
| A small-molecule inhibitor of human DNA polymerase η potentiates the effects of cisplatin in tumor cells MK Zafar, L Maddukuri, A Ketkar, NR Penthala, MR Reed, S Eddy, ... Biochemistry 57 (7), 1262-1273, 2018 | 37 | 2018 |
| Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin NR Madadi, H Zong, A Ketkar, C Zheng, NR Penthala, V Janganati, ... MedChemComm 6 (5), 788-794, 2015 | 37 | 2015 |
| N-Aroyl Indole Thiobarbituric Acids as Inhibitors of DNA Repair and Replication Stress Response Polymerases GE Coggins, L Maddukuri, NR Penthala, JH Hartman, S Eddy, A Ketkar, ... ACS chemical biology 8 (8), 1722-1729, 2013 | 34 | 2013 |
| Proteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitis MR Jain, Q Li, T Liu, J Rinaggio, A Ketkar, V Tournier, K Madura, ... Journal of proteome research 11 (3), 1791-1803, 2012 | 33 | 2012 |
| Antinociceptive effects of the 6-O-sulfate ester of morphine in normal and diabetic rats: Comparative role of mu-and delta-opioid receptors JSK Yadlapalli, BM Ford, A Ketkar, A Wan, NR Penthala, RL Eoff, ... Pharmacological research 113, 335-347, 2016 | 26 | 2016 |
| A structural basis for the role of nucleotide specifying residues in regulating the oligomerization of the Rv1625c adenylyl cyclase from M. tuberculosis AD Ketkar, AR Shenoy, UA Ramagopal, SS Visweswariah, K Suguna Journal of molecular biology 356 (4), 904-916, 2006 | 26 | 2006 |
| Inhibition of human DNA polymerases eta and kappa by indole-derived molecules occurs through distinct mechanisms A Ketkar, L Maddukuri, NR Penthala, MR Reed, MK Zafar, PA Crooks, ... ACS chemical biology 14 (6), 1337-1351, 2019 | 24 | 2019 |
| Residues in the RecQ C-terminal domain of the human Werner syndrome helicase are involved in unwinding G-quadruplex DNA A Ketkar, M Voehler, T Mukiza, RL Eoff Journal of Biological Chemistry 292 (8), 3154-3163, 2017 | 23 | 2017 |
| Synthesis, anticancer activity and molecular docking studies on a series of heterocyclic trans-cyanocombretastatin analogues as antitubulin agents NR Penthala, H Zong, A Ketkar, NR Madadi, V Janganati, RL Eoff, ... European journal of medicinal chemistry 92, 212-220, 2015 | 23 | 2015 |
| A new DNA polymerase I from Geobacillus caldoxylosilyticus TK4: cloning, characterization, and mutational analysis of two aromatic residues C Sandalli, K Singh, MJ Modak, A Ketkar, S Canakci, İ Demir, AO Belduz Applied microbiology and biotechnology 84, 105-117, 2009 | 23 | 2009 |
| Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity A Ketkar, MK Zafar, L Maddukuri, K Yamanaka, S Banerjee, M Egli, ... Chemical research in toxicology 26 (2), 221-232, 2013 | 20 | 2013 |
| Identification of a New Motif Required for the 3′–5′ Exonuclease Activity of Escherichia coli DNA Polymerase I (Klenow Fragment): THE RRRY MOTIF IS NECESSARY FOR THE BINDING … P Kukreti, K Singh, A Ketkar, MJ Modak Journal of biological chemistry 283 (26), 17979-17990, 2008 | 20 | 2008 |
| Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome protein L Maddukuri, A Ketkar, S Eddy, MK Zafar, WC Griffin, RL Eoff Journal of Biological Chemistry 287 (50), 42312-42323, 2012 | 18 | 2012 |
Leena MaddukuriUniversity of Arkansas for Medical SciencesVerified email at uams.edu
